Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

1997 • 7,814 citations

α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson’s disease and dementia with Lewy bodies

1998 • 2,898 citations

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1998 • 1,546 citations

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

1988 • 1,518 citations

Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

1997 • 1,241 citations

Identification of two distinct synucleins from human brain

1994 • 1,031 citations

Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species

1998 • 1,024 citations

Oxidative stress and the pathogenesis of Parkinson's disease

1996 • 967 citations

Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

1998 • 949 citations

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch

1995 • 826 citations

Oxidative Alterations in Alzheimer's Disease

1999 • 772 citations

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble α‐synuclein

1998 • 647 citations

Evidence of neuronal oxidative damage in Alzheimer's disease.

1996 • 602 citations

Dityrosine Cross-linking Promotes Formation of Stable α-Synuclein Polymers

2000 • 561 citations

Protein Nitration in Parkinsonʼs Disease

1998 • 551 citations

Mutant and Wild Type Human α-Synucleins Assemble into Elongated Filaments with Distinct Morphologies in Vitro

1999 • 510 citations

Oxidative Stress in Huntington's Disease

1999 • 491 citations

Distribution of tau proteins in the normal human central and peripheral nervous system.

1989 • 314 citations

Carbon Dioxide Enhancement of Peroxynitrite-Mediated Protein Tyrosine Nitration

1996 • 302 citations

Widespread Alterations of α-Synuclein in Multiple System Atrophy

1999 • 296 citations

Antibodies to ?-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease

1999 • 290 citations

Widespread Nitration of Pathological Inclusions in Neurodegenerative Synucleinopathies

2000 • 276 citations

Oxidative Stress and Motor Neurone Disease

1999 • 220 citations

A panel of epitope-specific antibodies detects protein domains distributed throughout human ?-synuclein in lewy bodies of Parkinson's disease

2000 • 219 citations

Neurodegeneration with Brain Iron Accumulation, Type 1 Is Characterized by α-, β-, and γ-Synuclein Neuropathology

2000 • 194 citations

[19] Antibodies that recognize nitrotyrosine

1996 • 190 citations

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for α-synuclein

1998 • 169 citations

Epitope map of neurofilament protein domains in cortical and peripheral nervous system Lewy bodies.

1991 • 161 citations

Oxidative Damage to Proteins, Lipids, and DNA in Cortical Brain Regions from Patients with Dementia with Lewy Bodies

1998 • 122 citations

Standardization of various applications of methacrylate embedding and silver methenamine for light and electron microscopy immunocytochemistry

1984 • 71 citations

[31] Nitric oxide donor generation from reactions of peroxynitrite

1999 • 12 citations