Phorbol ester-induced alteration of protein kinase C catalytic properties occurs at the membrane level and is not reproduced by physiological stimuli

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

The phorbol ester receptor: a phospholipid-regulated protein kinase

1985 • 522 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

Early changes in phosphatidylinositol and arachidonic acid metabolism in quiescent swiss 3T3 cells stimulated to divide by platelet-derived growth factor.

1981 • 492 citations

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

1985 • 387 citations

The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid.

1986 • 228 citations

Purification and immunochemical characterization of the two adrenal cortex mitochondrial cytochrome P-450-proteins

1978 • 136 citations

Activation of protein kinase C by non-phorbol tumor promoter, mezerein

1984 • 135 citations

Phorbol ester induces intracellular translocation of phospholipid/Ca²⁺ ‐dependent protein kinase and stimulates amylase secretion in isolated pancreatic acini

1984 • 102 citations

Altered catalytic properties of protein kinase C in phorbol ester treated cells

1986 • 60 citations

Activation of cellular protein kinase C and mode of inhibitory action of phospholipid-interacting compounds

1985 • 56 citations

Specific binding of [20-3H]12-deoxyphorbol 13-isobutyrate to phorbol ester receptor subclasses in mouse skin particulate preparations.

1983 • 53 citations

Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophils

1986 • 46 citations

Differential actions of phorbol ester and diacylglycerol on inhibition of granulosa cell maturation

1985 • 38 citations

Phorbol ester and 1,2‐diolein are not fully equivalent activators of protein kinase C in respect to phosphorylation of membrane proteins in vitro

1986 • 37 citations