Novel protein serine/threonine phosphatases: Variety is the spice of life

The development of Drosophila melanogaster

1994 • 3,057 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

On target with a new mechanism for the regulation of protein phosphorylation

1993 • 901 citations

Serine/threonine protein phosphatases

1995 • 635 citations

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

1997 • 625 citations

Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases.

1996 • 499 citations

The Myeloid Leukemia-associated Protein SET Is a Potent Inhibitor of Protein Phosphatase 2A

1996 • 463 citations

Crystal Structure of the Catalytic Subunit of Human Protein Phosphatase 1 and its Complex with Tungstate

1995 • 418 citations

Regulation of the Phosphorylation State and Microtubule-Binding Activity of Tau by Protein Phosphatase 2A

1996 • 389 citations

Molecular mechanisms of theprotein serine/threonine phosphatases

1996 • 365 citations

Structure and function of theprotein tyrosine phosphatases

1996 • 339 citations

The Structure, Role, and Regulation of Type 1 Protein Phosphatases

1992 • 295 citations

Inhibitors of protein kinases and phosphatases

1994 • 268 citations

A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus.

1994 • 261 citations

Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts.

1994 • 251 citations

The Tetratricopeptide Repeat Domain of Protein Phosphatase 5 Mediates Binding to Glucocorticoid Receptor Heterocomplexes and Acts as a Dominant Negative Mutant

1996 • 224 citations

PPX, a novel protein serine/threonine phosphatase localized to centrosomes.

1993 • 221 citations

Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.

1991 • 210 citations

A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae.

1996 • 206 citations

Yeast Protein Serine/Threonine Phosphatases: Multiple Roles and Diverse Regulation

1996 • 192 citations

Inhibitor‐2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase‐1 into a conformation with the specificity and regulatory properties of the native enzyme

1993 • 186 citations

Conservation analysis and structure prediction of the protein serine/threonine phosphatases

1994 • 177 citations

The SAPs, a New Family of Proteins, Associate and Function Positively with the SIT4 Phosphatase

1996 • 164 citations

High Complexity in the Expression of the B′ Subunit of Protein Phosphatase 2A0

1996 • 163 citations

Drosophila retinal degeneration C (rdgC) encodes a novel serine/threonine protein phosphatase

1992 • 158 citations

The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation

1996 • 155 citations

Identification of Protein‐Phosphatase‐1‐Binding Domains on the Glycogen and Myofibrillar Targetting Subunits

1996 • 150 citations

The PPZ Protein Phosphatases Are Important Determinants of Salt Tolerance in Yeast Cells

1995 • 145 citations

SIT4 protein phosphatase is required for the normal accumulation of SWI4, CLN1, CLN2, and HCS26 RNAs during late G1.

1992 • 144 citations

Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain

1997 • 135 citations

A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway.

1993 • 127 citations

[41] Nearest neighbor procedure for relating progressively aligned amino acid sequences

1990 • 107 citations

Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos

1996 • 92 citations

The PPZ protein phosphatases are involved in the maintenance of osmotic stability of yeast cells

1993 • 83 citations

The variable subunit associated with protein phosphatase 2A0 defines a novel multimember family of regulatory subunits

1996 • 77 citations

Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis.

1993 • 76 citations

A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway.

1993 • 71 citations

The gene PPG encodes a novel yeast protein phosphatase involved in glycogen accumulation.

1993 • 59 citations

The NH2-terminal Extension of Protein Phosphatase PPZ1 Has an Essential Functional Role

1996 • 59 citations

Inhibition of Protein Serine/Threonine Phosphatases by Fumonisin B1, a Mycotoxin

1996 • 57 citations

Both isoforms of protein phosphatase Z are essential for the maintenance of cell size and integrity in Saccharomyces cerevisiae in response to osmotic stress

1993 • 54 citations

Drosophila protein phosphatase V functionally complements a SIT4 mutant in Saccharomyces cerevisiae and its amino-terminal region can confer this complementation to a heterologous phosphatase catalytic domain.

1993 • 52 citations

Isolation and cloning of a protein-serine/threonine phosphatase from an archaeon

1995 • 51 citations

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.

1993 • 45 citations

Polymerase chain reactions using Saccharomyces, Drosophila and human DNA predict a large family of protein serine/threonine phosphatases

1992 • 43 citations

The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension.

1994 • 33 citations

PPQ, a novel protein phosphatase containing a Ser+Asn‐rich amino‐terminal domain, is involved in the regulation of protein synthesis

1993 • 31 citations

Biochemical characterization of recombinant yeast PPZ1, a protein phosphatase involved in salt tolerance

1995 • 29 citations

Drosophila ppy, a novel male specific protein serine/threonine phosphatase localised in somatic cells of the testis

1995 • 27 citations

Intracellular Signal Transduction

1996 • 13 citations