Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling

1995 • 2,907 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Nuclear targeting sequences — a consensus?

1991 • 1,908 citations

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.

1993 • 1,459 citations

A rapid finite difference algorithm, utilizing successive over‐relaxation to solve the Poisson–Boltzmann equation

1991 • 1,257 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1991 • 949 citations

On target with a new mechanism for the regulation of protein phosphorylation

1993 • 901 citations

Crystal structure of the p27Kip1 cyclin-dependent-kinase inibitor bound to the cyclin A–Cdk2 complex

1996 • 889 citations

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

1995 • 850 citations

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1995 • 821 citations

Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

1995 • 749 citations

Serine/threonine protein phosphatases

1995 • 635 citations

The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogue

1995 • 627 citations

Protein Serine/Threonine Phosphatases—New Avenues for Cell Regulation

1994 • 424 citations

Crystal Structure of the Catalytic Subunit of Human Protein Phosphatase 1 and its Complex with Tungstate

1995 • 418 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

The control of protein phosphatase‐1 by targetting subunits

1992 • 376 citations

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

1995 • 361 citations

The protein phosphatases involved in cellular regulation. Identification of the inhibitor-2 phosphatases in rabbit skeletal muscle

1984 • 330 citations

Signal integration at the level of protein kinases, protein phosphatases and their substrates

1992 • 314 citations

The protein phosphatases involved in cellular regulation

1985 • 261 citations

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

1995 • 253 citations

REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.

1995 • 229 citations

More on target with protein phosphorylation: conferring specificity by location.

1996 • 225 citations

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

1992 • 209 citations

Yeast Protein Serine/Threonine Phosphatases: Multiple Roles and Diverse Regulation

1996 • 192 citations

Inhibitor‐2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase‐1 into a conformation with the specificity and regulatory properties of the native enzyme

1993 • 186 citations

Crystal structure of a streptococcal protein G domain bound to an Fab fragment

1992 • 180 citations

Conservation analysis and structure prediction of the protein serine/threonine phosphatases

1994 • 177 citations

Molecular cloning and expression of the regulatory (RG1) subunit of the glycogen-associated protein phosphatase

1991 • 169 citations

Complete Primary Structure of Protein Phosphatase Inhibitor‐1 from Rabbit Skeletal Muscle

1982 • 163 citations

Amino acid sequence and expression of the hepatic glycogen‐binding (G_L‐subunit of protein phosphatase‐1

1995 • 161 citations

The p53-Binding Protein 53BP2 Also Interacts with Bcl2 and Impedes Cell Cycle Progression at G₂/M

1996 • 159 citations

GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae.

1992 • 158 citations

Purification of type 1 protein (serine/threonine) phosphatases by microcystin‐Sepharose affinity chromatography

1994 • 156 citations

Multiple Structural Elements Define the Specificity of Recombinant Human Inhibitor-1 as a Protein Phosphatase-1 Inhibitor^,

1996 • 155 citations

Identification of Protein‐Phosphatase‐1‐Binding Domains on the Glycogen and Myofibrillar Targetting Subunits

1996 • 150 citations

Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53

1995 • 130 citations

The isolation of novel inhibitory polypeptides of protein phosphatase 1 from bovine thymus nuclei.

1992 • 122 citations

Molecular Cloning of NIPP-1, a Nuclear Inhibitor of Protein Phosphatase-1, Reveals Homology with Polypeptides Involved in RNA Processing

1995 • 115 citations

DARPP-32, a dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Primary structure and homology with protein phosphatase inhibitor-1.

1986 • 105 citations

Regulation of protein phosphatase‐1_G from rabbit skeletal muscle

1989 • 102 citations

Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver‐ and muscle‐specific glycogen binding subunits of protein phosphatase 1

1996 • 99 citations

Subunit Structure and Regulation of Protein Phosphatase-1 in Rat Liver Nuclei

1995 • 99 citations

Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity

1990 • 98 citations

Protein Phosphatase Type 1 Interacts with Proteins Required for Meiosis and Other Cellular Processes in Saccharomyces cerevisiae

1996 • 97 citations

Identification of the Regions on the M₁₁₀ Subunit of Protein Phosphatase 1M That Interact with the M₂₁ Subunit and with Myosin

1997 • 93 citations

More on target with protein phosphorylation: conferring specificity by location

1996 • 93 citations

Purification of the hepatic glycogen‐associated form of protein phosphatase‐1 by microcystin‐Sepharose affinity chromatography

1995 • 89 citations

Inactivation of nuclear inhibitory polypeptides of protein phosphatase-1 (NIPP-1) by protein kinase A

1993 • 74 citations

The REG2 Gene of Saccharomyces cerevisiae Encodes a Type 1 Protein Phosphatase-Binding Protein That Functions with Reg1p and the Snf1 Protein Kinase to Regulate Growth

1996 • 71 citations

Interaction of protein phosphatase type 1 with a splicing factor

1996 • 64 citations

Mechanism of Inhibition of Protein Phosphatase 1 by DARPP-32: Studies with Recombinant DARPP-32 and Synthetic Peptides

1995 • 63 citations

Isolation and characterisation of active fragments of protein phosphatase inhibitor‐1 from rabbit skeletal muscle

1982 • 62 citations

Interaction of the Ribosomal Protein, L5, with Protein Phosphatase Type 1

1995 • 59 citations

Co-crystallization of the Catalytic Subunit of the Serine/Threonine Specific Protein Phosphatase 1 from Human in Complex with Microcystin LR

1994 • 42 citations

Full activation of a nuclear species of protein phosphatase-1 by phosphorylation with protein kinase A and casein kinase-2

1994 • 40 citations

SCD5, a suppressor of clathrin deficiency, encodes a novel protein with a late secretory function in yeast.

1996 • 34 citations

Distinct type-1 protein phosphatases are associated with hepatic glycogen and microsomes

1988 • 30 citations

Characterization of a Ribosomal Inhibitory Polypeptide of Protein Phosphatase‐1 from Rat Liver

1996 • 29 citations

The Florey Lecture, 1992. The secretion of proteins by cells

1992 • 23 citations

Serine/threonine protein

1990 • 5 citations

Deleted Work

1955 • 0 citations