Inhibitor‐2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase‐1 into a conformation with the specificity and regulatory properties of the native enzyme

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

MOLECULAR CHAPERONES

1991 • 1,089 citations

[7] Preparation of myosin and its subfragments from rabbit skeletal muscle

1982 • 963 citations

Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate

1991 • 853 citations

The Subunit Structure of Rabbit‐Skeletal‐Muscle Phosphorylase Kinase, and the Molecular Basis of Its Activation Reactions

1973 • 727 citations

THE ISOLATION AND CRYSTALLIZATION OF RABBIT SKELETAL MUSCLE PHOSPHORYLASE b

1958 • 660 citations

Protein phosphatases come of age

1989 • 616 citations

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1990 • 529 citations

An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues

1989 • 482 citations

[3] Expression and nitrogen-15 labeling of proteins for proton and nitrogen-15 nuclear magnetic resonance

1989 • 455 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

Enzymatic replication of the origin of the Escherichia coli chromosome.

1981 • 385 citations

The control of protein phosphatase‐1 by targetting subunits

1992 • 376 citations

One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis

1990 • 291 citations

The protein phosphatases involved in cellular regulation

1985 • 261 citations

Identification of Members of the Protein Phosphatase 1 Gene Family in the Rat and Enhanced Expression of Protein Phosphatase 1α Gene in Rat Hepatocellular Carcinomas

1990 • 227 citations

Identification of the major protein phosphatases in mammalian cardiac muscle which dephosphorylate phospholamban

1991 • 226 citations

Synergistic phosphorylation and activation of ATP-Mg-dependent phosphoprotein phosphatase by F A/GSK-3 and casein kinase II (PC0.7).

1984 • 212 citations

The MgATP-Dependent Protein Phosphatase and Protein Phosphatase 1 Have Identical Substrate Specificities

2005 • 191 citations

Reconstitution of a Mg‐ATP‐dependent protein phosphatase and its activation through a phosphorylation mechanism

1982 • 183 citations

Effects of Ca2+ on the conformation and enzymatic activity of smooth muscle myosin.

1985 • 170 citations

Molecular cloning and expression of the regulatory (RG1) subunit of the glycogen-associated protein phosphatase

1991 • 169 citations

Proteolysis of smooth muscle myosin by Staphylococcus aureus protease: preparation of heavy meromyosin and subfragment 1 with intact 20,000-dalton light chains

1985 • 156 citations

Characterisation of a Reconstituted Mg‐ATP‐Dependent Protein Phosphatase

1983 • 154 citations

Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A

1987 • 128 citations

Cell cycle oscillation of phosphatase inhibitor-2 in rat fibroblasts coincident with p34cdc2 restriction

1990 • 120 citations

Expression of the catalytic subunit of phosphorylase phosphatase (protein phosphatase-1) in Escherichia coli.

1992 • 114 citations

Discovery of a protein phosphatase activity encoded in the genome of bacteriophage λ. Probable identity with open reading frame 221

1989 • 112 citations

Isolation and structural analysis of a peptide containing the novel tyrosyl-glucose linkage in glycogenin.

1988 • 111 citations

[40] Protein phosphatase inhibitor-1 and inhibitor-2 from rabbit skeletal muscle

1988 • 109 citations

Two isoforms of protein phosphatase 1 may be produced from the same gene

1988 • 108 citations

Regulation of protein phosphatase‐1_G from rabbit skeletal muscle

1989 • 102 citations

The protein phosphatases involved in cellular regulation

1986 • 99 citations

Drosophila contains three genes that encode distinct isoforms of protein phosphatase 1

1990 • 92 citations

The glycogen‐binding subunit of protein phosphatase‐1_g from rabbit skeletal muscle

1989 • 85 citations

Protein phosphatase 1 activity in Drosophila mutants with abnormalities in mitosis and chromosome condensation

1990 • 74 citations

A Kinetic Analysis of the Effects of Inhibitor-1 and Inhibitor-2 on the Activity of Protein Phosphatase-1

1983 • 74 citations

Identification and characterization of an ATP.Mg-dependent protein phosphatase from pig brain.

1985 • 59 citations

Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II

1986 • 59 citations

A myofibrillar protein phosphatase from rabbit skeletal muscle contains the β isoform of protein phosphatase‐1 complexed to a regulatory subunit which greatly enhances the dephosphorylation of myosin

1992 • 57 citations

Partial structure and hormonal regulation of rabbit liver inhibitor-1; distribution of inhibitor-1 and inhibitor-2 in rabbit and rat tissues

1989 • 55 citations

Temperature-sensitive production of rabbit muscle glycogen phosphorylase in Escherichia coli

1991 • 50 citations

The protein phosphatases of Drosophila melanogaster and their inhibitors

1987 • 50 citations

Analysis of the in vivo phosphorylation state of protein phosphatase inhibitor-2 from rabbit skeletal muscle by fast-atom bombardment mass spectrometry

1987 • 48 citations

[36] Glycogen synthase kinase-3 from rabbit skeletal muscle

1983 • 37 citations

Identification of protein phosphatases‐1 and 2A and inhibitor‐2 in oocytes of the starfish Asterias rubens and Marthasterias glacialis

1987 • 37 citations

Purification and characterization of growth-associated H1 histone kinase from Novikoff hepatoma cells.

1990 • 35 citations

Phosphoprotein phosphatase inhibitor-2. Identification as a species of molecular weight 31,000 in rabbit muscle, liver, and other tissues.

1985 • 29 citations

Is Phosphorylase Phosphatase a Manganese Metalloenzyme?

1978 • 23 citations

Sequence Homologies between Type 1 and Type 2A Protein Phosphatases

1987 • 12 citations