Purification of the saxitoxin receptor of the sodium channel from rat brain.

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels

1980 • 3,334 citations

The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation.

1962 • 2,522 citations

The binding of saxitoxin and tetrodotoxin to excitable tissue

1977 • 369 citations

The receptor for tetrodotoxin and saxitoxin. A structural hypothesis

1975 • 295 citations

Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.

1978 • 270 citations

Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes.

1979 • 214 citations

Actions of saxitoxin on peripheral neuromuscular systems.

1965 • 200 citations

Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin.

1980 • 199 citations

A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.

1976 • 195 citations

Binding of scorpion toxin to receptor sites associated with sodium channels in frog muscle. Correlation of voltage-dependent binding with activation.

1979 • 158 citations

Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

1980 • 129 citations

Ion flux studies of voltage-sensitive sodium channels in synaptic nerve-ending particles.

1981 • 120 citations

Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophoruselectricus

1980 • 113 citations

Solubilization of a specific tetrodotoxin-binding component from garfish olfactory nerve membrane

1972 • 104 citations

Sodium channels in presynaptic nerve terminals. Regulation by neurotoxins.

1980 • 93 citations

Solubilized tetrodotoxin binding component from the electroplax of Electrophorus electricus. Stability as a function of mixed lipid-detergent micelle composition

1979 • 82 citations

Solubilization and partial characterization of the tetrodotoxin binding component from nerve axons

1973 • 62 citations

Size characteristics of the solubilized saxitoxin receptor of the voltage-sensitive sodium channel from rat brain.

1980 • 45 citations