The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve

A quantitative description of membrane current and its application to conduction and excitation in nerve

1952 • 21,965 citations

Stability constants of metal-ion complexes

1964 • 3,797 citations

The effect of sodium ions on the electrical activity of the giant axon of the squid

1949 • 3,479 citations

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

1943 • 2,733 citations

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

The action of calcium on the electrical properties of squid axons

1957 • 1,853 citations

Membranes, Ions, and Impulses

1968 • 1,002 citations

Cation Selective Glass Electrodes and their Mode of Operation

1962 • 844 citations

The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve

1971 • 751 citations

Depolarization and calcium entry in squid giant axons

1971 • 729 citations

Movements of labelled calcium in squid giant axons

1957 • 668 citations

The Gramicidin A Transmembrane Channel: A Proposed π _(L,D) Helix

1971 • 665 citations

Charges and Potentials at the Nerve Surface

1968 • 567 citations

The Selective Inhibition of Delayed Potassium Currents in Nerve by Tetraethylammonium Ion

1967 • 490 citations

Pharmacological Modifications of the Sodium Channels of Frog Nerve

1968 • 479 citations

Discreteness of Conductance Change in Bimolecular Lipid Membranes in the Presence of Certain Antibiotics

1970 • 405 citations

Voltage clamp experiments on internally perfused giant axons.

1965 • 400 citations

The Gramicidin A Transmembrane Channel: Characteristics of Head-to-Head Dimerized π _(L,D) Helices

1971 • 384 citations

Membrane currents in isolated frog nerve fibre under voltage clamp conditions

1958 • 355 citations

The Initiation of Spike Potential in Barnacle Muscle Fibers under Low Intracellular Ca++

1964 • 327 citations

Beiträge zur allgemeinen Muskel- und Nervenphysiologie

1902 • 327 citations

Effect of Divalent Cations on Potassium Conductance of Squid Axons

1969 • 304 citations

Membranes, ions, and impulses.

1969 • 281 citations

Geochemische Verteilungsgesetze der Elemente

1923 • 265 citations

A new voltage clamp method for Ranvier nodes

1969 • 248 citations

Wave Functions for Electron-Excess Color Centers in Alkali Halide Crystals

1960 • 247 citations

Ion Binding by Synthetic Macrocyclic Compounds

1971 • 243 citations

Ionic Currents Underlying Activity in the Giant Axon of the Squid

1949 • 243 citations

Sodium currents in the myelinated nerve fibre of Xenopus laevis investigated with the voltage clamp technique

1959 • 226 citations

New Measurements of the Capacity and the Resistance of the Myelin Sheath and the Nodal Membrane of the Isolated Frog Nerve Fiber

1955 • 215 citations

Electrolyte solutions

1975 • 190 citations

Direct determination of membrane resting potential and action potential in single myelinated nerve fibres

1951 • 173 citations

Ammonium Ion Currents in the Squid Giant Axon

1969 • 172 citations

A Molecular Structural Basis for the Excitation Properties of Axons

1964 • 166 citations

The Effects of External Potassium and Long Duration Voltage Conditioning on the Amplitude of Sodium Currents in the Giant Axon of the Squid, Loligo pealei

1969 • 158 citations

Basis of Tetrodotoxin's Selectivity in Blockage of Squid Axons

1967 • 138 citations

A Theory of Passive Ion Flux through Axon Membranes

1964 • 136 citations

Nerve Excitation

1969 • 113 citations

A Chemically Specified Molecular Mechanism Underlying Excitation in Nerve: A Hypothesis

1964 • 102 citations

A method for recording resting and action potentials in the isolated myelinated nerve fibre of the frog

1957 • 99 citations

AN ANALYSIS OF CONDUCTANCE CHANGES IN SQUID AXON

1959 • 98 citations

THE PENETRATION OF SOME CATIONS INTO MUSCLE

1959 • 92 citations

Role of divalent cations in excitation of squid giant axons

1967 • 92 citations

Effects of Tetrodotoxin on Excitability of Squid Giant Axons in Sodium-Free Media

1967 • 77 citations

The role of ions in axon surface reactions to toxic organic compounds

1948 • 76 citations

The effect of reducing extracellular pH on the membrane currents of the Ranvier node

1969 • 75 citations

Die Wirkung von Tetra�thylammoniumchlorid auf die Membranstr�me Ranvierscher Schn�rringe von Xenopus laevis

1967 • 72 citations

MEMBRANE MACROMOLECULES AND NERVE EXCITABILITY: A PHYSICO‐CHEMICAL INTERPRETATION OF EXCITATION IN SQUID GIANT AXONS

1966 • 70 citations

THE MACROMOLECULAR PROPERTIES OF EXCITABLE MEMBRANES*

1961 • 64 citations

Excitation of internally perfused squid giant axons in sodium-free media.

1965 • 56 citations

ALKALI CATION SELECTIVITY OF SQUID AXON MEMBRANE*

1966 • 53 citations

Restoration of Sodium-deficient Frog Nerve Fibres by Onium Ions

1957 • 52 citations

The specificity of the initial current in myelinated nerve fibres of Xenopus laevis. Voltage clamp experiments

1963 • 49 citations

Individual Activity of Calcium Ions in Pure Solutions of CaCl2 and in Mixtures

1968 • 49 citations

Excitation of squid giant axons in sodium-free external media

1966 • 42 citations

Sodium influxes in internally perfused squid giant axon during voltage clamp

1969 • 41 citations

Restoration of Sodium-deficient Frog Nerve Fibres by an Isotonic Solution of Guanidinium Chloride

1956 • 40 citations

Potential functions for hydrogen bond interactions I. A modified lippincott-schroeder potential function for NH⋯O interaction between peptide groups

1970 • 39 citations

A Pharmacological Analysis of the Ionic Channels of Nerve

1967 • 34 citations

The Hydration of Sodium Ions Crossing the Nerve Membrane

1971 • 33 citations

Evidence against Hydrogen–Calcium Competition Model for Activation of Electrically Excitable Membranes

1971 • 33 citations

Molecular mechanisms of membrane ionic permeability changes

1971 • 33 citations

Effect of tetrodotoxin on the early outward currents in perfused giant axons.

1967 • 26 citations

Hydrogen Ion and the Activation of Electrically Excitable Membranes

1969 • 26 citations

Current Separations in Myxicola Giant Axons

1969 • 21 citations

Potential functions for hydrogen bond interactions

1971 • 20 citations

Crystal structure of triaminoguanidinium chloride, (NH₂.NH)₃C.Cl

1957 • 18 citations

Weitere Untersuchungen �ber den passiven Ionentransport durch die erregbare Membran des Ranvierknotens

1961 • 16 citations

Die Wirkung von Guanidinhydrochlorid auf die Erregungsprozesse an isolierten markhaltigen Nervenfasern

1958 • 16 citations

Permeability of the squid axon membrane to several organic molecules

1961 • 15 citations

Energy-Transducing Reaction in Biologyical Members. II. Molecular Mechanism for the Permeability Changes in Nerve During the Paggage of an Action Potential

1969 • 14 citations

69. The stabilities of complexes of thallium(I) and the alkali metals with uramildiacetic acid

1963 • 13 citations

Potential functions for hydrogen bond interactions

1971 • 9 citations

Effects of tetrodotoxin on the action potential in NA-free media

1966 • 9 citations

The Electrical Conductivity and Ionization Constants of Organic Compounds

1914 • 6 citations

Functional Uptake of Hydrazine by Frog Nerve in Sodium-deficient Ringer's Solution

1962 • 3 citations

Effects of tetrodotoxin on the action potential in Na-free media

1967 • 1 citations