The sodium channel from rat brain. Reconstitution of neurotoxin-activated ion flux and scorpion toxin binding from purified components.

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

A simple procedure for removal of triton X-100 from protein samples

1973 • 857 citations

The Permeability of the Sodium Channel to Metal Cations in Myelinated Nerve

1972 • 367 citations

The sodium channel from rat brain. Purification and subunit composition.

1984 • 352 citations

Activation of the action potential Na+ ionophore by neurotoxins. An allosteric model

1977 • 256 citations

Purification of the saxitoxin receptor of the sodium channel from rat brain.

1981 • 223 citations

Membrane potential-dependent binding of scorpion toxin to the action potential Na+ ionophore. Studies with a toxin derivative prepared by lactoperoxidase-catalyzed iodination

1977 • 221 citations

Use of a lipophilic cation for determination of membrane potential in neuroblastoma-glioma hybrid cell suspensions

1979 • 219 citations

Neurotoxin binding to receptor sites associated with voltage-sensitive sodium channels in intact, lysed, and detergent-solubilized brain membranes.

1979 • 214 citations

A new method for labelling saxitoxin and its binding to non-myelinated fibres of the rabbit vagus, lobster walking leg, and garfish olfactory nerves.

1976 • 195 citations

Active transport of sodium and potassium ions by the sodium and potassium ion-activated adenosine triphosphatase from renal medulla. Reconstitution of the purified enzyme into a well defined in vitro transport system.

1977 • 194 citations

Sea anemone toxin and scorpion toxin share a common receptor site associated with the action potential sodium ionophore.

1978 • 187 citations

Reconstitution of carbamylcholine-dependent sodium ion flux and desensitization of the acetylcholine receptor from Torpedo californica.

1978 • 176 citations

The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunits.

1982 • 163 citations

[44] Preparation of lipid extracts

1969 • 156 citations

Glycosylation is required for maintenance of functional sodium channels in neuroblastoma cells.

1983 • 154 citations

Scorpion neurotoxin — A presynaptic toxin which affects both Na+ and K+ channels in axons

1975 • 132 citations

Ion flux studies of voltage-sensitive sodium channels in synaptic nerve-ending particles.

1981 • 120 citations

Binding of scorpion toxin to receptor sites associated with voltage-sensitive sodium channels in synaptic nerve ending particles.

1978 • 113 citations

Potential-dependent interaction of toxin from venom of the scorpion Buthus eupeus with sodium channels in myelinated fibre. Voltage clamp experiments

1980 • 97 citations

Functional reconstitution of the purified sodium channel protein from rat sarcolemma.

1982 • 96 citations

Binding of sea anemone toxin to receptor sites associated with gating system of sodium channel in synaptic nerve endings in vitro.

1980 • 95 citations

Reconstitution of neurotoxin-stimulated sodium transport by the voltage-sensitive sodium channel purified from rat brain.

1982 • 94 citations

Binding of scorpion toxins to rat brain synaptosomal fraction. Effects of membrane potential, ions, and other neurotoxins

1980 • 92 citations

Binding of scorpion and sea anemone neurotoxins to a common site related to the action potential Na+ ionophore in neuroblastoma cells

1978 • 85 citations

Analysis of saxitoxin binding in isolated rat synaptosomes using a rapid filtration assay

1978 • 73 citations

Comparison of ionic selectivity of batrachotoxin-activated channels with different tetrodotoxin dissociation constants.

1979 • 67 citations

Binding to saxitoxin to electrically excitable neuroblastoma cells.

1978 • 62 citations

One-to-one binding of a purified scorpion toxin to Na channels

1977 • 54 citations

[45] Chromatography on columns of silicic acid

1969 • 53 citations

Scorpion toxin: Specific binding to rat synaptosomes

1978 • 49 citations

Reconstitution of the voltage-sensitive sodium channel of rat brain from solubilized components.

1981 • 44 citations

The Specificity of the Sodium Channel for Monovalent Cations.

1981 • 37 citations

Molecular characterization, reconstitution, and "transport-specific fractionation" of the saxitoxin binding protein/Na+ gate of mammalian brain.

1980 • 35 citations

The association of tetrodotoxin-sensitive, sodium-selective ionophore of brain membranes with liposomes

1980 • 19 citations