Expression of metalloproteinases and inhibitors in the differentiation of P19CL6 cells into cardiac myocytes

New functions for the matrix metalloproteinases in cancer progression

2002 • 5,937 citations

Matrix Metalloproteinases

1999 • 3,774 citations

Metalloproteinase inhibitors: biological actions and therapeutic opportunities

2002 • 1,159 citations

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

1999 • 790 citations

Axis Development and Early Asymmetry in Mammals

1999 • 740 citations

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

2002 • 727 citations

The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1

2002 • 701 citations

Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

1982 • 674 citations

The Soluble Catalytic Domain of Membrane Type 1 Matrix Metalloproteinase Cleaves the Propeptide of Progelatinase A and Initiates Autoproteolytic Activation

1996 • 564 citations

The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

1990 • 450 citations

Primitive-Streak Origin of the Cardiovascular System in Avian Embryos

1993 • 362 citations

Matrix Metalloproteinase-2 and −9 Differentially Regulate Smooth Muscle Cell Migration and Cell-Mediated Collagen Organization

2003 • 306 citations

Defective trophoblast function in mice with a targeted mutation of Ets2

1998 • 299 citations

Disruption of the myocardial extracellular matrix leads to cardiac dysfunction

2000 • 277 citations

A Wnt- and β-catenin-dependent pathway for mammalian cardiac myogenesis

2003 • 248 citations

Regulation of Matrix Metalloproteinase Activity^a

1994 • 221 citations

Structural Analysis and Promoter Characterization of the Human Collagenase-3 Gene (MMP13)

1997 • 198 citations

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

2003 • 197 citations

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development

2004 • 189 citations

Cardiac Morphogenesis—Recent Research Advances

1987 • 164 citations

Matrix metalloproteinase activity expression in infarcted, noninfarcted and dilated cardiomyopathic human hearts

1996 • 156 citations

Epithelial-Mesenchymal Transformations in Early Avian Heart Development

1996 • 139 citations

Differentiation of Beating Cardiac Muscle Cells from a Derivative of P19 Embryonal Carcinoma Cells.

1996 • 137 citations

Role of Matrix Metalloproteinases in Vascular Remodeling

2003 • 127 citations

Matrix Metalloproteinase Disruption of the Extracellular Matrix and Cardiac Dysfunction

2002 • 120 citations

Imbalance Between Tissue Inhibitor of Metalloproteinase-4 and Matrix Metalloproteinases During Acute Myoctardial Ischemia-Reperfusion Injury

2003 • 117 citations

Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA

1989 • 114 citations

Differential gene expression of extracellular matrix components in dilated cardiomyopathy

1996 • 102 citations

A Wnt- and beta-catenin-dependent pathway for mammalian cardiac myogenesis

2003 • 100 citations

Degradation of Type IV Collagen by Matrix Metalloproteinases Is an Important Step in the Epithelial-Mesenchymal Transformation of the Endocardial Cushions

2000 • 91 citations

Spatial and temporal expression of the 72-kDa type IV collagenase (MMP-2) correlates with development and differentiation of valves in the embryonic avian heart

1997 • 65 citations

Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene

2002 • 64 citations

MMP-2 expression during early avian cardiac and neural crest morphogenesis

2000 • 63 citations

Microarray analysis of global changes in gene expression during cardiac myocyte differentiation

2002 • 54 citations

Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion

2004 • 24 citations

Expression of tissue inhibitor of metalloproteinases (TIMPs) during early cardiac development

2002 • 24 citations