A CD80-transfected human breast cancer cell variant induces HER-2/neu?specific T cells in HLA-A*02?matched situations in vitro as well as in vivo

SYFPEITHI: database for MHC ligands and peptide motifs

1999 • 2,307 citations

Tumor Rejection After Direct Costimulation of CD8 ⁺ T Cells by B7-Transfected Melanoma Cells

1993 • 1,154 citations

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 • 1,076 citations

Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines.

1995 • 542 citations

HLA class I antigen downregulation in human cancers: T-cell immunotherapy revives an old story

1999 • 366 citations

Immunotherapy of malignancy by in vivo gene transfer into tumors.

1993 • 320 citations

Identification of HLA-A2–Restricted T-Cell Epitopes Derived From the MUC1 Tumor Antigen for Broadly Applicable Vaccine Therapies

1999 • 301 citations

Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors.

1998 • 220 citations

Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

1999 • 206 citations

Quantification of cytokine mRNA expression by RT PCR in samples of previously frozen blood

1997 • 169 citations

Costimulation of tumor-reactive CD4+ and CD8+ T lymphocytes by B7, a natural ligand for CD28, can be used to treat established mouse melanoma.

1994 • 145 citations

Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach

2000 • 134 citations

Identification of Her-2/Neu CTL epitopes using double transgenic mice expressing HLA-A2.1 and human CD.8

1997 • 107 citations

Real-Time Quantitative Polymerase Chain Reaction Assessment of Immune Reactivity in Melanoma Patients After Tumor Peptide Vaccination

2000 • 104 citations

Protective antitumor immunity induced by immunization with completely allogeneic tumor cells.

1996 • 89 citations

Tumor cells cotransfected with interleukin‐7 and B7.1 genes induce CD25 and CD28 on tumor‐infiltrating T lymphocytes and are strong vaccines

1995 • 85 citations

Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in anIn vitro melanoma model

1999 • 83 citations

Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor.

1989 • 83 citations

Can Co‐stimulated Tumor Immunity be Therapeutically Efficacious?

1995 • 81 citations

Generation of tumor-specific CTLs from melanoma patients by using peripheral blood stimulated with allogeneic melanoma tumor cell lines. Fine specificity and MART-1 melanoma antigen recognition.

1995 • 81 citations

A MAGE-A1 HLA-A A*0201 epitope identified by mass spectrometry.

2001 • 80 citations

HLA and cancer: from research to clinical impact

1998 • 77 citations

Vaccination of Melanoma Patients with an Allogeneic, Genetically Modified Interleukin 2-Producing Melanoma Cell Line

2000 • 76 citations

Vaccination of Women with Metastatic Breast Cancer, Using a Costimulatory Gene (CD80)-Modified, HLA-A2-Matched, Allogeneic, Breast Cancer Cell Line: Clinical and Immunological Results

2003 • 74 citations

Immunobiology of HER-2/ neu oncoprotein and its potential application in cancer immunotherapy

2004 • 68 citations

Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes

2000 • 64 citations

Incidence and prognosis in early onset breast cancer

2002 • 62 citations

Vaccination of Melanoma Patients with Interleukin 4 Gene-Transduced Allogeneic Melanoma Cells

1999 • 59 citations

Evaluation of pre-existent immunity in patients with primary breast cancer: molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells.

2003 • 56 citations

Cell-free tumor antigen peptide-based cancer vaccines

1997 • 53 citations

Vaccination with a Mixed Vaccine of Autogenous and Allogeneic Breast Cancer Cells and Tumor Associated Antigens CA15-3, CEA and CA125 - Results in Immune and Clinical Responses in Breast Cancer Patients

2000 • 48 citations

Resistance to natural killer cell lysis conferred by TAP1/2 genes in human antigen-processing mutant cells.

1994 • 45 citations

Expression of B7.1 (CD80) in a renal cell carcinoma line allows expansion of tumor-associated cytotoxic T lymphocytes in the presence of an alloresponse

2000 • 44 citations

Allogeneic murine melanoma cell vaccine

1996 • 42 citations

Existent proliferative responses of peripheral blood mononuclear cells from healthy donors and ovarian cancer patients to HER-2 peptides.

1997 • 40 citations

Identification of HER-2/neu immunogenic epitopes presented by renal cell carcinoma and other human epithelial tumors

2001 • 39 citations

Induction of Autologous Tumor-Specific Cytotoxic T-Lymphocyte Activity Against a Human Renal Carcinoma Cell Line by B7–1 (CD80) Costimulation

1996 • 36 citations

Inflammatory breast cancer treated with surgery, chemotherapy and allogeneic tumor cell/BCG immunotherapy

1982 • 34 citations

Protective and Therapeutic Immunity Against Leukemia Induced by Irradiated B7-1 (CD80)-Transduced Leukemic Cells

1997 • 33 citations

Identification of Tumor-Specific Antibodies in Patients With Breast Cancer Vaccinated With Gene-Modified Allogeneic Tumor Cells

2003 • 32 citations

Strong Immunogenic Potential of a B7 Retroviral Expression Vector: Generation of HLA-B7-Restricted CTL Response Against Selectable Marker Genes

1998 • 30 citations

Human Melanoma Cells Transfected with the B7-2 Co-Stimulatory Molecule Induce Tumor-Specific CD8+ Cytotoxic T Lymphocytes In Vitro

1998 • 29 citations

Tumor Cells Expressing Major Histocompatibility Complex Class II and B7 Activation Molecules Stimulate Potent Tumor-Specific Immunity

1993 • 29 citations

Induction of Melanoma Antigen-Specific Cytotoxic T Lymphocytes In Vitro by Stimulation with B7-Expressing Human Melanoma Cell Lines

1998 • 24 citations

Cervical carcinoma cells transfected with the CD80 gene elicit a primary cytotoxic T lymphocyte response specific for HPV 16 E7 antigens.

1997 • 23 citations

Development of immunogenic colorectal cancer cell lines for vaccination: Expression of CD80 (B7.1) is not sufficient to restore impaired primary T cell activation in vitro

1995 • 21 citations

Soluble HLA-A2.1 restricted peptides that are recognized by influenza virus specific cytotoxic T lymphocytes

1991 • 20 citations

Strategies for the Development of Vaccines to Treat Breast Cancer

1998 • 19 citations

CD80-transfected human breast and ovarian tumor cell lines: improved immunogenicity and induction of cytolytic CD8+ T lymphocytes.

1995 • 17 citations

Interleukin-12 requires initial CD80-mediated T-cell activation to support immune responses toward human breast and ovarian carcinoma

1999 • 16 citations

Allogeneic Breast Cancer Cell Vaccines

2003 • 15 citations

Tumor-associated antigen profiling in breast and ovarian cancer: mRNA, protein or T cell recognition?

2003 • 14 citations

Adjuvant chemo‐lmmunotherapy in stage II carcinoma of the breast

1986 • 12 citations

Gene transfer of costimulatory molecules into a human colorectal cancer cell line: requirement of CD54, CD80 and class II MHC expression for enhanced immunogenicity

1998 • 10 citations

Potential of CD80-transfected human breast carcinoma cells to induce peptide-specific T lymphocytes in an allogeneic human histocompatibility leukocyte antigens (HLA)-A2.1+-matched situation

1999 • 10 citations

Inhibition of the growth of human melanoma xenografts in nude mice by human tumor-specific cytotoxic T-cells

1990 • 6 citations

Construction of Immunogenic Tumor Cell Surfaces by Somatic Gene Transfer

1998 • 3 citations

Einsatz tumorassoziierter Antigene in der Immuntherapie und Immundiagnostik des Mammakarzinoms

2003 • 2 citations