Threshold levels of gene expression of the melanoma antigen gp100 correlate with tumor cell recognition by cytotoxic T lymphocytes

Real time quantitative PCR.

1996 • 6,155 citations

Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response

1996 • 684 citations

Tumor antigens recognized by T cells

1997 • 552 citations

The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

1996 • 552 citations

Cancer vaccines based on the identification of genes encoding cancer regression antigens

1997 • 395 citations

Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2'-deoxycytidine.

1994 • 292 citations

Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A.

1997 • 286 citations

Expression of Melan-A (MART1) in Benign Melanocytic Nevi and Primary Cutaneous Malignant Melanoma

1998 • 230 citations

Heterogeneous expression of immunotherapy candidate proteins gp100, MART-1, and tyrosinase in human melanoma cell lines and in human melanocytic lesions.

1997 • 187 citations

Immunophenotyping of melanomas for tyrosinase: implications for vaccine development.

1995 • 177 citations

Heterogeneous expression of melanoma-associated antigens and HLA-A2 in metastatic melanoma in vivo

1998 • 166 citations

Immune selection after antigen-specific immunotherapy of melanoma

1999 • 162 citations

A monoclonal antibody specific for cells of the melanocyte lineage.

1988 • 143 citations

Analysis of Expression of the Melanoma-Associated Antigens MART-1 and gp lOO in Metastatic Melanoma Cell Lines and in In Situ Lesions

1996 • 131 citations

Comparative Analysis of the In Vivo Expression of Tyrosinase, MART-1/Melan-A, and gp100 in Metastatic Melanoma Lesions: Implications for Immunotherapy

1998 • 94 citations

A novel cytolysis assay using fluorescent labeling and quantitative fluorescent scanning technology

1999 • 87 citations

Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in anIn vitro melanoma model

1999 • 83 citations

MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte.

1997 • 48 citations

Transcription of the gene encoding melanoma-associated antigen gp100 in tissues and cell lines other than those of the melanocytic lineage

1997 • 47 citations

Development and Characterization of Melanoma Cell Lines Established by Fine-Needle Aspiration Biopsy: Advances in the Monitoring of Patients with Metastatic Melanoma

1999 • 31 citations

Expression of gp 100 in Melanoma Metastases Resected Before or After Treatment with IFN?? and IL-2

1996 • 29 citations

Melan-A/MART-1 Antigen Expression in Cutaneous and Ocular Melanomas

1997 • 16 citations