The Role of Metalloelastase in Immune Complex-Induced Acute Lung Injury

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

1997 • 1,463 citations

Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability.

1996 • 1,132 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Chemotactic activity of elastin-derived peptides.

1980 • 519 citations

T cell gelatinases mediate basement membrane transmigration in vitro.

1995 • 507 citations

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

1996 • 496 citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

1990 • 459 citations

Role of Oxidants and Antioxidants in the Induction of AP-1, NF-κB, and Glutathione S-Transferase Gene Expression

1996 • 457 citations

The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome

1999 • 428 citations

Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membrane.

1996 • 416 citations

Matrix metalloproteinase-mediated extracellular matrix protein degradation in human pulmonary emphysema.

1998 • 334 citations

Migration of Eosinophils through Basement Membrane ComponentsIn Vitro: Role of Matrix Metalloproteinase-9

1997 • 261 citations

Mouse macrophage elastase. Purification and characterization as a metalloproteinase

1981 • 260 citations

Matrix Metalloproteinases

1999 • 245 citations

Gelatinase B–deficient Mice Are Resistant to Experimental Bullous Pemphigoid

1998 • 236 citations

Increased Release of Matrix Metalloproteinase-9 in Bronchoalveolar Lavage Fluid and by Alveolar Macrophages of Asthmatics

1997 • 219 citations

Role of Matrix Metalloproteinases and Their Inhibition in Cutaneous Wound Healing and Allergic Contact Hypersensitivity

1999 • 209 citations

Role for macrophage inflammatory protein-2 in lipopolysaccharide-induced lung injury in rats.

1996 • 200 citations

Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression.

1994 • 200 citations

Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase.

1992 • 197 citations

Matrix metalloproteinase-3–dependent generation of a macrophage chemoattractant in a model of herniated disc resorption

2000 • 180 citations

Triggering the Induction of Myofibroblast and Fibrogenesis by Airway Epithelial Shedding

2001 • 159 citations

Expression and Localization of Matrix Metalloproteinase-12 in the Aorta of Cholesterol-Fed Rabbits

1998 • 153 citations

Role of Stromelysin 1 and Gelatinase B in Experimental Acute Lung Injury

2001 • 149 citations

Characterization of Matrix Metalloproteinases Produced by Rat Alveolar Macrophages

1999 • 144 citations

Matrix metalloproteinase deficiencies affect contact hypersensitivity: Stromelysin-1 deficiency prevents the response and gelatinase B deficiency prolongs the response

1999 • 131 citations

Regulatory Effects of Endogenous Protease Inhibitors in Acute Lung Inflammatory Injury

1999 • 101 citations

In vivo suppression of immune complex-induced alveolitis by secretory leukoproteinase inhibitor and tissue inhibitor of metalloproteinases 2.

1993 • 82 citations