Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections

Immunobiology of Dendritic Cells

2000 • 6,653 citations

Functional Role of Type I and Type II Interferons in Antiviral Defense

1994 • 2,437 citations

Impaired immune and acute-phase responses in interleukin-6-deficient mice

1994 • 1,776 citations

Immune Response in Mice that Lack the Interferon-γ Receptor

1993 • 1,570 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

1993 • 1,197 citations

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

The Influence of Antigen Organization on B Cell Responsiveness

1993 • 701 citations

Impairment of T-cell-dependent B-cell responses and B-l cell development in CD19-deficient mice

1995 • 663 citations

A crucial role for B cells in neuroinvasive scrapie

1997 • 503 citations

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

1995 • 496 citations

Disruption of the Cr2 Locus Results in a Reduction in B-1a Cells and in an Impaired B Cell Response to T-Dependent Antigen

1996 • 494 citations

Dendritic Cells Interact Directly with Naive B Lymphocytes to Transfer Antigen and Initiate Class Switching in a Primary T-Dependent Response

1998 • 454 citations

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1998 • 380 citations

Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

1987 • 363 citations

PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION

1969 • 345 citations

The Role of Antibody Concentration and Avidity in Antiviral Protection

1997 • 265 citations

GENETICS OF A NEW IgVH (T15 IDIOTYPE) MARKER IN THE MOUSE REGULATING NATURAL ANTIBODY TO PHOSPHORYLCHOLINE

1974 • 247 citations

Virus-triggered acquired immunodeficiency by cytotoxic T-cell-dependent destruction of antigen-presenting cells and lymph follicle structure.

1991 • 231 citations

A Quasi-Monoclonal Mouse

1996 • 204 citations

B cells extract and present immobilized antigen: implications for affinity discrimination

2000 • 199 citations

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice.

1996 • 185 citations

PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION

1970 • 163 citations

Protective T Cell–Independent Antiviral Antibody Responses Are Dependent on Complement

1999 • 155 citations

Complement-Independent, Peroxide-Induced Antibody Lysis of Platelets in HIV-1-Related Immune Thrombocytopenia

2001 • 154 citations

IgD can largely substitute for loss of IgM function in B cells

1998 • 141 citations

Analysis of the Virus-Specific and Nonspecific B Cell Response to a Persistent B-Lymphotropic Gammaherpesvirus

2000 • 122 citations

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice

1999 • 112 citations

Genetic mapping of lymphocytic choriomeningitis virus pathogenicity: virulence in guinea pigs is associated with the L RNA segment

1985 • 89 citations

In vivo polyclonal B-lymphocyte activation elicited by murine viruses

1990 • 82 citations

Complement deficiency and autoimmunity

1998 • 76 citations

Escape of Thymocytes and Mature T Cells from Clonal Deletion Due to Limiting Tolerogen Expression Levels

1994 • 57 citations

Involvement of CD4+Cells in Lymphocytic Choriomeningitis Virus-Induced Autoimmune Anaemia and Hypergammaglobulinaemia

1994 • 52 citations

Interleukin 6 and plasma cell neoplasias

1989 • 38 citations

Functional in vivo MHC class II loading by endogenously synthesized glycoprotein during viral infection.

1997 • 28 citations

Autoimmune responses as assessed by hypergammaglobulinemia and the presence of autoantibodies in patients with chronic hepatitis C.

1993 • 21 citations

Propagation of Lactic Dehydrogenase-EIevating Virus in Cell Culture.

1966 • 18 citations

Oligoclonal immunoglobulin bands in serum in association with chronic viral hepatitis.

1990 • 11 citations

Disruption of T Cell Tolerance to Self-Immunoglobulin Causes Polyclonal B Cell Stimulation Followed by Inactivation of Responding Autoreactive T Cells

2000 • 9 citations

PERSISTENT GENERALIZED LYMPHADENOPATHY: CLINICAL CHARACTERISTICS OF A LYMPHADENOPATHY SYNDROME IN INTRAVENOUS DRUG ABUSERS

1986 • 3 citations