Analysis of the Virus-Specific and Nonspecific B Cell Response to a Persistent B-Lymphotropic Gammaherpesvirus

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Impaired immune and acute-phase responses in interleukin-6-deficient mice

1994 • 1,776 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Interleukin-6 in Biology and Medicine

1993 • 1,398 citations

Humoral Immunity Due to Long-Lived Plasma Cells

1998 • 1,223 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

Mice deficient for the CD40 ligand

1994 • 753 citations

Complete sequence and genomic analysis of murine gammaherpesvirus 68

1997 • 736 citations

Depletion of CD4 ⁺ T Cells in Major Histocompatibility Complex Class II-Deficient Mice

1991 • 673 citations

How B and T cells talk to each other

1994 • 659 citations

The role of nasopharyngeal lymphoid tissue

1992 • 532 citations

Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells.

1996 • 515 citations

The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

1997 • 437 citations

IgG2a restriction of murine antibodies elicited by viral infections.

1987 • 429 citations

Patterns of lymphatic drainage in the adult laboratory rat.

1971 • 397 citations

Bone marrow is a major site of long-term antibody production after acute viral infection

1995 • 384 citations

Polyclonal Ig production after Epstein-Barr virus infection of human lymphocytes in vitro

1977 • 378 citations

The role of CD40 in the regulation of humoral and cell-mediated immunity

1994 • 376 citations

Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo

1992 • 351 citations

In Situ Studies of the Primary Immune Response to (4-Hydroxy-3-Nitrophenyl)Acetyl. V. Affinity Maturation Develops in Two Stages of Clonal Selection

1998 • 349 citations

Virological and pathological features of mice infected with murine gammaherpesvirus 68

1992 • 316 citations

Systemic autoimmune disease arises from polyclonal B cell activation.

1987 • 314 citations

Macrophages Are the Major Reservoir of Latent Murine Gammaherpesvirus 68 in Peritoneal Cells

1999 • 290 citations

Lung Epithelial Cells Are a Major Site of Murine Gammaherpesvirus Persistence

1998 • 257 citations

Murine gammaherpesvirus 68: a model for the study of gammaherpesvirus pathogenesis

1998 • 227 citations

Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells

1993 • 192 citations

Virally induced modulation of murine IgG antibody subclasses.

1988 • 162 citations

Pathogenesis of an Infectious Mononucleosis-like Disease Induced by a Murine γ-Herpesvirus: Role for a Viral Superantigen?

1997 • 157 citations

Anti-DNA autoantibodies in (NZB X NZW)F1 mice are clonally heterogeneous, but the majority share a common idiotype.

1982 • 143 citations

Absence of splenic latency in murine gammaherpesvirus 68-infected B cell-deficient mice

1996 • 132 citations

CD4⁺T cell-mediated control of a γ-herpesvirus in B cell-deficient mice is mediated by IFN-γ

1999 • 129 citations

Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells

1996 • 127 citations

Epstein-Barr virus and the B cell: that's all it takes

1996 • 125 citations

X-Linked Agammaglobulinemia Patients Are Not Infected with Epstein-Barr Virus: Implications for the Biology of the Virus

1999 • 123 citations

Epstein-Barr virus-transformed lymphocytes produce monoclonal autoantibodies that react with antigens in multiple organs

1984 • 112 citations

Antibody-forming cells in the nasal-associated lymphoid tissue during primary influenza virus infection.

1998 • 110 citations

Kinetic Analysis of the Specific Host Response to a Murine Gammaherpesvirus

1998 • 108 citations

Antibody formation in mouse bone marrow. I. Evidence for the development of plaque-forming cells in situ.

1974 • 105 citations

Cytokine- and Ig-producing T cells in mucosal effector tissues: analysis of IL-5- and IFN-gamma-producing T cells, T cell receptor expression, and IgA plasma cells from mouse salivary gland-associated tissues.

1992 • 98 citations

Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.

1994 • 97 citations

Non-Antigen-Specific B-Cell Activation following Murine Gammaherpesvirus Infection Is CD4 Independent In Vitro but CD4 Dependent In Vivo

1999 • 96 citations

Antibody formation in mouse bone marrow

1974 • 92 citations

Immunological control of a murine gammaherpesvirus independent of CD8+ T cells.

1999 • 91 citations

Respiratory virus infection of mice provokes a permanent humoral immune response

1994 • 90 citations

Influenza virus-specific antibody-secreting cells in the murine lung during primary influenza virus infection

1986 • 87 citations

Administration of anti-IFN-gamma antibody to beta 2-microglobulin-deficient mice delays influenza virus clearance but does not switch the response to a T helper cell 2 phenotype.

1994 • 86 citations

Gamma interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68

1997 • 83 citations

Cytokine production in the immune response to murine gammaherpesvirus 68

1996 • 75 citations

Superantigens and retroviral infection: insights from mouse mammary tumor virus

1994 • 74 citations

Requirement for CD40 Ligand, CD4⁺T Cells, and B Cells in an Infectious Mononucleosis-Like Syndrome

1999 • 72 citations

B cell activation by cytomegalovirus.

1983 • 71 citations

Multiple autoantibodies following cytomegalovirus infection: virus distribution and specificity of autoantibodies.

1988 • 68 citations

Suppression of murine collagen‐induced arthritis by nasal administration of collagen

1997 • 64 citations

Smooth-muscle antibodies and other tissue antibodies in cytomegalovirus infection.

1975 • 60 citations

Mechanism of virus-induced Ig subclass shifts.

1994 • 58 citations

Quantitative Analysis of the Acute and Long-Term CD4⁺T-Cell Response to a Persistent Gammaherpesvirus

1999 • 56 citations

Epstein-Barr virus (EBV) glycoprotein gp350 expressed on transfected cells resistant to natural killer cell activity serves as a target antigen for EBV-specific antibody-dependent cellular cytotoxicity

1991 • 56 citations

Longitudinal Analysis of the Acute Sendai Virus-Specific CD4+ T Cell Response and Memory

1998 • 50 citations

B-cell activation following murine cytomegalovirus infection: implications for autoimmunity.

1993 • 44 citations

Murine Cytomegalovirus Infection-Induced Polyclonal B Cell Activation Is Independent of CD4+T Cells and CD40

1998 • 42 citations

IFN-^γis a potent inducer of Ig secretion by sort-purified murine B cella activated through the mlg, but not the CD40,signaling pathway

1996 • 41 citations

Distinctive Kinetics of the Antibody-Forming Cell Response to Sendai Virus Infection of Mice in Different Anatomical Compartments

1995 • 37 citations

CD4+ T cell responses in mice lacking MHC class II molecules specifically on B cells

1998 • 36 citations

Distribution of plaque-forming cells in the mouse for a protein antigen. Evidence for highly active parathymic lymph nodes following intraperitoneal injection of hen lysozyme.

1976 • 36 citations

Matching antibody class with pathogen type and portal of entry: cognate mechanisms regulate local isotype expression patterns in lymph nodes draining the respiratory tract of mice inoculated with respiratory viruses, according to virus replication competence and site of inoculation.

1997 • 32 citations

Antibodies to Eukaryotic, including Autologous, Native DNA are Produced during BK Virus Infection, but not after Immunization with Non‐Infectious BK DNA

1992 • 31 citations

Sendai virus glycoproteins are T cell-dependent B cell mitogens

1983 • 31 citations

Clonal origins of lymphoproliferative disease induced by Epstein-Barr virus

1986 • 28 citations

Lambda2 light chains in normal mouse immunoglobulins.

1978 • 26 citations

Characterization of neutralizing monoclonal antibodies to murine cytomegalovirus

1990 • 23 citations

Murine anti-cytomegalovirus monoclonal antibodies with autoreactivity.

1991 • 19 citations

Influenza virus hemagglutinin induces differentiation of mature resting B cells and growth arrest of immature WEHI-231 lymphoma cells.

1994 • 13 citations

Turnover of T Cells in Murine Gammaherpesvirus 68-Infected Mice

1999 • 12 citations

Analysis of serum antibody repertoires by isoelectric focusing and capillary blotting onto nitrocellulose paper

1986 • 10 citations