Prevention of Kidney Ischemia/Reperfusion-induced Functional Injury and JNK, p38, and MAPK Kinase Activation by Remote Ischemic Pretreatment

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

Signal Transduction by the JNK Group of MAP Kinases

2000 • 4,096 citations

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

2000 • 1,703 citations

Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation

1997 • 750 citations

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1999 • 676 citations

Small Stress Proteins as Novel Regulators of Apoptosis

1996 • 614 citations

Human hsp27, Drosophila hsp27 and human alphaB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death.

1996 • 568 citations

Stimulation of the Stress-Activated Mitogen-Activated Protein Kinase Subfamilies in Perfused Heart

1996 • 531 citations

Jun N-Terminal Kinase/Stress-Activated Protein Kinase (JNK/SAPK) Is Required for Lipopolysaccharide Stimulation of Tumor Necrosis Factor Alpha (TNF-α) Translation: Glucocorticoids Inhibit TNF-α Translation by Blocking JNK/SAPK

1997 • 497 citations

HSP27 phosphorylation-mediated resistance against actin fragmentation and cell death induced by oxidative stress.

1996 • 471 citations

Tumor Necrosis Factor ä-Induced E-selectin Expression Is Activated by the Nuclear Factor-κB and c-JUN N-terminal Kinase/p38 Mitogen-activated Protein Kinase Pathways

1997 • 355 citations

Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways

1999 • 295 citations

The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion

1994 • 266 citations

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD

1999 • 261 citations

Protective effects of renal ischemic preconditioning and adenosine pretreatment: role of A₁ and A₃receptors

2000 • 232 citations

Ischemic Preconditioning Activates MAPKAPK2 in the Isolated Rabbit Heart

2000 • 177 citations

The role of differential activation of p38‐mitogen‐activated protein kinase in preconditioned ventricular myocytes

2000 • 167 citations

Responses of the ischemic acute renal failure kidney to additional ischemic events

1984 • 116 citations

Laboratory Study: Ischemic Preconditioning Attenuates Functional, Metabolic, and Morphologic Injury from Ischemic Acute Renal Failure in the Rat

1999 • 111 citations

Ischaemia‐reperfusion injury in the rat kidney: the effect of preconditioning

1997 • 105 citations

A “Second Window of Protection” Occurs 24 h After Ischemic Preconditioning in the Rat Heart

1998 • 102 citations

Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

1999 • 97 citations

Acquired resistance to acute renal failure

1987 • 95 citations

Ischemic Acute Renal Failure Induces Differential Expression of Small Heat Shock Proteins

2000 • 84 citations

Post-ischemic acute renal failure protects proximal tubules from O2 deprivation injury, possibly by inducing uremia

1994 • 77 citations

Attenuation of reperfusion injury by renal ischaemic preconditioning: the role of nitric oxide

2000 • 76 citations

Ischemic preconditioning

1997 • 39 citations

Obstruction of proximal tubules initiates cytoresistance against hypoxic damage

1995 • 39 citations

Mechanisms of renal repair and survival following acute injury.

1998 • 38 citations

Attenuation of injury due to unilateral renal ischemia: delayed effects of contralateral nephrectomy.

1984 • 33 citations

Inhibition of Myocardial TNF‐α Production by Heat Shock: A Potential Mechanism of Stress‐Induced Cardioprotection against Postischemic Dysfunction^a

1999 • 32 citations

Postischemic proximal tubular resistance to oxidant stress and Ca2+ ionophore-induced attack. Implications for reperfusion injury.

1995 • 24 citations