Unconventional Splicing of HAC1/ERN4 mRNA Required for the Unfolded Protein Response

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus.

1996 • 1,306 citations

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1988 • 1,292 citations

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

1993 • 1,197 citations

A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the Unfolded Protein Response

1996 • 1,017 citations

The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response

1997 • 886 citations

A transmembrane protein with a cdc2+CDC28-related kinase activity is required for signaling from the ER to the nucleus

1993 • 814 citations

Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells

1987 • 442 citations

tRNA Ligase Is Required for Regulated mRNA Splicing in the Unfolded Protein Response

1996 • 440 citations

Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic‐leucine zipper motif is required for the unfolded protein‐response pathway

1996 • 363 citations

Immunoglobulin Binding Protein (BiP) Function Is Required to Protect Cells from Endoplasmic Reticulum Stress but Is Not Required for the Secretion of Selective Proteins

1997 • 346 citations

The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC

1997 • 327 citations

Endoplasmic Reticulum Stress-induced mRNA Splicing Permits Synthesis of Transcription Factor Hac1p/Ern4p That Activates the Unfolded Protein Response

1997 • 283 citations

Protein functions in pre-mRNA splicing

1997 • 272 citations

The Yeast tRNA Splicing Endonuclease: A Tetrameric Enzyme with Two Active Site Subunits Homologous to the Archaeal tRNA Endonucleases

1997 • 235 citations

The tunicamycins — useful tools for studies on glycoproteins

1981 • 227 citations

Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge

1997 • 214 citations

The unfolded-protein-response pathway in yeast

1994 • 154 citations

Substrate recognition and splice site determination in yeast tRNA splicing

1988 • 153 citations

Saccharomyces cerevisiae IRE2/HAC1 is involved in IRE1-mediated KAR2 expression

1996 • 119 citations

Generation of a Mammalian Cell Line Deficient in Glucose-regulated Protein Stress Induction through Targeted Ribozyme Driven by a Stress-inducible Promoter

1995 • 104 citations

Establishment of a chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94

1992 • 95 citations

The cellular response to unfolded proteins: intercompartmental signaling

1994 • 81 citations

Competitive Inhibition of a Set of Endoplasmic Reticulum Protein Genes (GRP78, GRP94, and ERp72) Retards Cell Growth and Lowers Viability after Ionophore Treatment

1991 • 75 citations

Another Bridge between Kingdoms: tRNA Splicing in Archaea and Eukaryotes

1997 • 69 citations

RNA splicing: Unexpected spliceosome diversity

1996 • 33 citations