Perioperative Small-Dose S(+)-Ketamine Has No Incremental Beneficial Effects on Postoperative Pain When Standard-Practice Opioid Infusions Are Used

Preemptive Analgesia—Treating Postoperative Pain by Preventing the Establishment of Central Sensitization

1993 • 1,661 citations

Acute Opioid Tolerance

2000 • 868 citations

Mechanisms of hyperalgesian and morphine tolerance: a current view of their possible interactions

1995 • 828 citations

Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes

1999 • 533 citations

A Review of the Pharmacokinetics and Pharmacodynamics of Remifentanil

1999 • 375 citations

Spinal cord pharmacology of pain

1995 • 342 citations

Wind‐up and the NMDA receptor complex from a clinical perspective

2000 • 311 citations

Rapid Development of Tolerance to Analgesia During Remifentanil Infusion in Humans

1998 • 301 citations

Postoperative Pain

1993 • 247 citations

The Benefits of Intraoperative Small-Dose Ketamine on Postoperative Pain After Anterior Cruciate Ligament Repair

2000 • 228 citations

Rapid Development of Tolerance to Analgesia During Remifentanil Infusion in Humans

1998 • 212 citations

The Effect of Ketamine on Opioid-Induced Acute Tolerance: Can It Explain Reduction of Opioid Consumption with Ketamine-Opioid Analgesic Combinations?

2000 • 197 citations

Preemptive Ketamine Decreases Postoperative Narcotic Requirements in Patients Undergoing Abdominal Surgery

1997 • 190 citations

Preemptive Ketamine Decreases Postoperative Narcotic Requirements in Patients Undergoing Abdominal Surgery

1997 • 154 citations

Effect of racemic mixture and the (S+)-isomer of ketamine on temporal and spatial summation of pain

1996 • 145 citations

Lack of Rapid Development of Opioid Tolerance During Alfentanil and Remifentanil Infusions for Postoperative Pain

1999 • 100 citations

Recent advances in the physiology and pharmacology of pain: plasticity and its implications for clinical analgesia

1991 • 83 citations

Pre-emptive analgesia: evidence, current status and future directions.

1995 • 83 citations

Postoperative Pain Management After Intraoperative Remifentanil

1999 • 61 citations

Lack of Rapid Development of Opioid Tolerance During Alfentanil and Remifentanil Infusions for Postoperative Pain

1999 • 53 citations

Brain kinetics of (R)- and (S)-[N-methyl-11C]ketamine in the rhesus monkey studied by positron emission tomography (PET)

1994 • 40 citations

Evaluation of Pain After Arthroscopically Assisted Anterior Cruciate Ligament Reconstruction

1997 • 35 citations

The status of pre-emptive analgesia

1995 • 13 citations