Brain kinetics of (R)- and (S)-[N-methyl-11C]ketamine in the rhesus monkey studied by positron emission tomography (PET)

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Excitatory Amino Acid Neurotransmission: NMDA Receptors and Hebb-Type Synaptic Plasticity

1988 • 484 citations

Effects of ketamine on sensory perception: evidence for a role of N-methyl-D-aspartate receptors.

1992 • 412 citations

Noncompetitive excitatory amino acid receptor antagonists

1990 • 361 citations

The NMDA-receptor antagonist CPP abolishes neurogenic ‘wind-up pain’ after intrathecal administration in humans

1992 • 302 citations

Synthesis of L- and D-[methyl-11C]methionine.

1987 • 213 citations

Modulation of Glutamate Receptors: Molecular Mechanisms and Functional Implications

1989 • 198 citations

Radioligand binding to central phencyclidine recognition sites is dependent on excitatory amino acid receptor agonists

1986 • 182 citations

Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity

1990 • 152 citations

Possible central role of nitric oxide in conditions clinically similar to cerebral malaria

1992 • 140 citations

N-methyl-D-aspartate receptor regulation of uncompetitive antagonist binding in rat brain membranes: kinetic analysis.

1988 • 102 citations

Striatal kinetics of [11C]-(+)-nomifensine and 6-[18F]fluoro-L-dopa in Parkinson's disease measured with positron emission tomography

2009 • 75 citations

A Two-Compartment Description and Kinetic Procedure for Measuring Regional Cerebral [¹¹C]Nomifensine Uptake Using Positron Emission Tomography

1990 • 66 citations

Cerebral pharmacodynamics of anaesthetic and subanaesthetic doses of ketamine in the normoventilated pig

1993 • 51 citations

Optical resolution of asymmetric amines by preferential crystallization as lasalocid salts

1977 • 46 citations

In vivo labelling of the NMDA receptor channel complex by [3H]MK-801

1988 • 45 citations

The chiral forms of ketamine as probes for NMDA receptor functions in humans

1991 • 44 citations

Ketamine and midazolam decrease cerebral blood flow and consequently their own rate of transport to the brain: An application of mass balance pharmacokinetics with a changing regional blood flow

1992 • 43 citations

In vivo study of nmda-sensitive glutamate receptor by fluorothienylcycloexylpiperidine, a possible ligand for positron emission tomography

1991 • 26 citations

Synthesis and labelling with ¹⁸F of an MK 801 analogue: [¹⁸F]5‐(β‐fluoruethyl)‐10,11‐dihydro‐5H‐dibenzocycloheptene‐5,10‐imine

1989 • 17 citations

The Absolute Configuration of Ketamine -- a General Anaesthetic. The Crystal Structure of the (R,R)-Tartrate Salt of (--)-(S)-Ketamine.

1991 • 7 citations

18F-PCP analogs for positron emission tomography (PET)

1987 • 3 citations