The H-ras oncogene product p21 and prognosis in human breast cancer

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Statistical Methods in Medical Research.

1972 • 4,731 citations

Histological Grading and Prognosis in Breast Cancer

1957 • 2,897 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Expression of Cellular Oncogenes in Human Malignancies

1984 • 840 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1981 • 736 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Malignant Activation of a K- ras Oncogene in Lung Carcinoma But Not in Normal Tissue of the Same Patient

1984 • 395 citations

Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses

1979 • 315 citations

Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virus

1979 • 270 citations

Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases

1984 • 226 citations

Monoclonal antibodies of predefined specificity detect activated ras gene expression in human mammary and colon carcinomas.

1984 • 223 citations

A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient.

1984 • 207 citations

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.

1985 • 195 citations

Expression of the 21,000 molecular weight ras protein in a spectrum of benign and malignant human mammary tissues.

1986 • 140 citations

Prognostic significance of the expression of a ras protein with a molecular weight of 21,000 by human breast cancer.

1987 • 130 citations

Expression of p21 ras oncoproteins in human cancers.

1986 • 119 citations

Human malignant tumours of the breast, as compared to their respective normal tissue, have elevated expression of the Harvey ras oncogene.

1984 • 103 citations

Amplified expression of p21 ras protein in hormone-dependent mammary carcinomas of humans and rodents

1985 • 94 citations

Identification of a normal vertebrate cell protein related to the p21 src of harvey murine sarcoma virus

1980 • 91 citations

A simple method for the determination of oestrogen receptor concentrations in breast tumours and other tissues

1975 • 73 citations

Elevated ras oncogene expression correlates with lymph node metastases in breast cancer patients.

1986 • 60 citations

Quantitation of Harvey <italic>ras</italic> p21 Enhanced Expression in Human Breast and Colon Carcinomas

1987 • 51 citations

Differential expression of cellular oncogenes in benign and malignant human breast tissue

1986 • 50 citations

Comparative Study of Harvey-<i>RAS</i> Oncogene Expression with Conventional Clinicopathologic Parameters of Breast Cancer

1986 • 37 citations

Mutant ras proteins and cell transformation

1984 • 28 citations

Expression of p21ras gene products in breast cancer relates to histological types and to receptor and nodal status

1988 • 23 citations