Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile

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Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

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Release of Excess Amyloid β Protein from a Mutant Amyloid β Protein Precursor

1993 • 909 citations

Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer's Disease

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Multinuclear NMR Studies on the Energy Metabolism of Glial and Neuronal Cells

1993 • 878 citations

Oxidatively modified proteins in aging and disease1,2 1Guest Editor: Earl Stadtman 2This article is part of a series of reviews on “Oxidatively Modified Proteins in Aging and Disease.” The full list of papers may be found on the homepage of the journal.

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Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death

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APPSW Transgenic Mice Develop Age-related Aβ Deposits and Neuropil Abnormalities, but no Neuronal Loss in CA1

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Specific Expression of N‐Acetylaspartate in Neurons, Oligodendrocyte‐Type‐2 Astrocyte Progenitors, and Immature Oligodendrocytes In Vitro

1992 • 504 citations

N -Acetylaspartate in neuropsychiatric disorders

1995 • 422 citations

REGULATION OF GENE EXPRESSION BY HYPERTONICITY

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Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

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Probable Alzheimer disease: diagnosis with proton MR spectroscopy.

1995 • 295 citations

MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons

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Glial Fibrillary Acidic Protein: Regulation by Hormones, Cytokines, and Growth Factors

1994 • 230 citations

Nonlinear Decrease over Time in N‐Acetyl Aspartate Levels in the Absence of Neuronal Loss and Increases in Glutamine and Glucose in Transgenic Huntington's Disease Mice

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N ‐acetyl‐L‐aspartate and other amino acid metabolites in Alzheimer's disease brain

1992 • 175 citations

A Proton Magnetic Resonance Spectroscopy Study of Age-related Changes in Frontal Lobe Metabolite Concentrations

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¹H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease

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Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease

1999 • 100 citations

Alzheimer’s disease and total plasma aminothiols

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In-vivo proton MR-spectroscopy of the human brain: Assessment of N-acetylaspartate (NAA) reduction as a marker for neurodegeneration

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Glutathione Cycle Impairment Mediates Aβ-induced Cell Toxicity

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Choline in the aging brain

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Lack of β-Amyloidosis in transgenic mice expressing low levels of familial Alzheimer's disease missense mutations

1996 • 26 citations