Blocking Neutrophil Influx Reduces DNA Damage in Hyperoxia-Exposed Newborn Rat Lung

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

1994 • 1,303 citations

Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis

1999 • 639 citations

Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model.

1997 • 579 citations

Neonatal Chronic Lung Disease in Extremely Immature Baboons

1999 • 500 citations

Mechanisms initiating lung injury in the preterm

1998 • 421 citations

Functional and pathological effects of prolonged hyperoxia in neonatal mice

1998 • 420 citations

The apoptosis cascade -- morphological and immunohistochemical methods for its visualization

1999 • 316 citations

Chronic Lung Injury in Preterm Lambs

1999 • 290 citations

Oxygen Toxicity in Mouse Lung: Pathways to Cell Death

1998 • 262 citations

Cellular Oxygen Toxicity

1996 • 260 citations

Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation.

1998 • 178 citations

Activated Leukocytes Oxidatively Damage DNA, RNA, and the Nucleotide Pool through Halide-Dependent Formation of Hydroxyl Radical

2000 • 145 citations

Neutrophils cause oxidative DNA damage in alveolar epithelial cells

1999 • 140 citations

DNA damage and cell cycle checkpoints in hyperoxic lung injury: braking to facilitate repair

2001 • 121 citations

Lung Inflammation in Hyperoxia Can Be Prevented By Antichemokine Treatment in Newborn Rats

2000 • 114 citations

Apoptosis in Neonatal Murine Lung Exposed to Hyperoxia

2001 • 110 citations

Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits

2001 • 103 citations

Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand

2001 • 95 citations

Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats

2001 • 95 citations

Apoptosis in Various Organs of Preterm Infants: Histopathologic Study of Lung, Kidney, Liver, and Brain of Ventilated Infants

2001 • 76 citations

p53-independent induction ofGADD45andGADD153in mouse lungs exposed to hyperoxia

2000 • 68 citations

Transforming Growth Factor-β1 Suppresses Serum Deprivation-induced Death of A549 Cells through Differential Effects on c-Jun and JNK Activities

2000 • 66 citations

Bcl-2 Family Gene Expression during Severe Hyperoxia Induced Lung Injury

2000 • 61 citations

Colocalization of cytokeratin 18 and villin in type III alveolar cells (brush cells) of the rat lung

1994 • 51 citations

Pulmonary apoptosis in aged and oxygen-tolerant rats exposed to hyperoxia

1998 • 49 citations

Hyperoxic exposure of developing rat lung decreases tropoelastin mRNA levels that rebound postexposure

1993 • 45 citations

Prenatal dexamethasone administration to premature rats exposed to prolonged hyperoxia: A new rat model of pulmonary fibrosis (bronchopulmonary dysplasia)

1997 • 43 citations

Chemokine mRNA Alterations in Newborn and Adult Mouse Lung During Acute Hyperoxia

1998 • 41 citations

Brief Exposure to 95% Oxygen Alters Surfactant Protein D and mRNA in Adult Rat Alveolar and Bronchiolar Epithelium

1999 • 28 citations

Effect of the 21-Aminosteroid U74389G on Oxygen-Induced Free Radical Production, Lipid Peroxidation, and Inhibition of Lung Growth in Neonatal Rats

1999 • 27 citations

Handbook of biostatistics : a review and text

2000 • 11 citations

Oxidants and Antioxidants: What Role Do They Play in Chronic Lung Disease?

1999 • 8 citations

Chronic Lung Disease of Early Infancy: Role of Neutrophils

1999 • 6 citations

Modulation of pan-cadherin expression in alveolar epithelial cells of mini pigs with pulmonary fibrosis

1994 • 4 citations

Proteolytic Enzymes and Their Inhibitors in Lung Health and Disease

1999 • 2 citations