Immediate early gene induction after neonatal hypoxia-ischemia

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Stimulus-Transcription Coupling in the Nervous System: Involvement of the Inducible Proto-Oncogenes fos and jun

1991 • 2,666 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

The regulation and function of c-fos and other immediate early genes in the nervous system

1990 • 2,392 citations

The influence of immaturity on hypoxic‐ischemic brain damage in the rat

1981 • 2,073 citations

The use of c-fos as a metabolic marker in neuronal pathway tracing

1989 • 1,390 citations

Isolation and Characterization of Full-Length cDNA Clones for Human α-, β-, and γ-Actin mRNAs: Skeletal but Not Cytoplasmic Actins Have an Amino-Terminal Cysteine that Is Subsequently Removed

1983 • 1,220 citations

Role of ion flux in the control of c-fos expression

1986 • 1,006 citations

A gene activated by growth factors is related to the oncogene v-jun.

1988 • 771 citations

Effect of Ischemia on the In Vivo Release of Striatal Dopamine, Glutamate, and γ‐Aminobutyric Acid Studied by Intracerebral Microdialysis

1988 • 704 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA

1982 • 668 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.

1983 • 546 citations

Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction.

1989 • 502 citations

Localization of 70-kDa stress protein induction in gerbil brain after ischemia

1988 • 465 citations

Cloning of tetradecanoyl phorbol ester-induced 'primary response' sequences and their expression in density-arrested Swiss 3T3 cells and a TPA non-proliferative variant.

1987 • 360 citations

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments.

1984 • 352 citations

Glutamate receptor agonists increase the expression of Fos, Fra, and AP‐1 DNA binding activity in the mammalian brain

1989 • 330 citations

Synthesis of a Stress Protein Following Transient Ischemia in the Gerbil

1985 • 270 citations

D1-dopamine receptor agonists selectively activate striatal c-fos independent of rotational behaviour

1989 • 266 citations

MK-801 protects the neonatal brain from hypoxic-ischemic damage

1987 • 261 citations

Regulation of jun -B Messenger RNA and AP-1 Activity by Light and a Circadian Clock

1992 • 215 citations

Localization of 70 kDa Stress Protein mRNA Induction in Gerbil Brain after Ischemia

1991 • 202 citations

The fos Oncogene

1987 • 196 citations

In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia

1991 • 180 citations

Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study

1989 • 178 citations

Effects of kainic acid-induced seizures and ischemia on c-fos-like proteins in rat brain

1990 • 175 citations

Regional Expression of Heat Shock Protein-70 mRNA and c-Fos mRNA following Focal Ischemia in Rat Brain

1992 • 171 citations

Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: A current perspective

1990 • 170 citations

Direct Evidence for Acute and Massive Norepinephrine Release in the Hippocampus during Transient Ischemia

1989 • 169 citations

Neuropathology of remote hypoxic-ischemic damage in the immature rat

1991 • 168 citations

The TIS11 primary response gene is a member of a gene family that encodes proteins with a highly conserved sequence containing an unusual Cys-His repeat.

1991 • 162 citations

MK-801 prevents hypobaric-ischemic neuronal degeneration in infant rat brain

1989 • 161 citations

Neurotransmitter alterations in a model of perinatal hypoxic‐ischemic brain injury

1983 • 158 citations

Proto-oncogene c-fos is transiently induced in the rat cerebral cortex after forebrain ischemia

1989 • 149 citations

Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex

1991 • 146 citations

Continuous lidocaine infusion and focal feline cerebral ischemia.

1990 • 140 citations

Hypoxia—ischemia induces heat shock protein-like (HSP72) immunoreactivity in neonatal rat brain

1990 • 139 citations

Heat Shock Protein hsp72 Induction in Cortical and Striatal Astrocytes and Neurons following Infarction

1991 • 135 citations

Neuroprotective Effects of L-Kynurenine on Hypoxia—Ischemia and NMDA Lesions in Neonatal Rats

1992 • 132 citations

Adrenergic receptors mediate changes in c-fos mRNA levels in brain

1989 • 126 citations

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

1986 • 116 citations

70-kDa heat shock protein and c-fos gene expression after transient ischemia.

1990 • 116 citations

Activation of specific glutamate receptor subtypes increases c-fos proto-oncogene expression in primary cultures of neonatal rat cerebellar granule cells

1987 • 100 citations

Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus

1991 • 100 citations

Noradrenergic activation of immediate early genes in rat cerebral cortex

1991 • 96 citations

Effects of hypoxia-ischemia and seizures on neuronal and glial-like c-fos protein levels in the infant rat

1990 • 95 citations

Transient ischemia stimulates glial fibrillary acid protein and vimentin gene expression in the gerbil neocortex, striatum and hippocampus

1992 • 94 citations

MK-801 Prevents Hippocampal Neurodegeneration in Neonatal Hypoxic-Ischemic Rats

1989 • 87 citations

Nerve growth factor increases in adult rat brain after hypoxic injury

1989 • 83 citations

Spinal c-fos induction by sensory stimulation in neonatal rats

1990 • 78 citations

Variations in c-fos gene expression during rat brain development

1988 • 77 citations

Ischemic induction of protooncogene expression in gerbil brain.

1991 • 77 citations

Calcium Accumulation during the Evolution of Hypoxic—Ischemic Brain Damage in the Immature Rat

1988 • 76 citations

Effects of hypoxia‐ischemia on monoamine metabolism in the immature brain

1984 • 74 citations

c-fos mRNA levels are increased by the cellular stressors, heat shock and sodium arsenite.

1988 • 72 citations

Effects of perinatal stroke on striatal amino acid efflux in rats studied with in vivo microdialysis.

1991 • 46 citations

Immunohistochemistry of c‐fos in Mouse Brain During Postnatal Development: Basal Levels and Changing Response to Metrazol and Kainate Injection

1991 • 45 citations

Neuronal Damage after Repeated 5 Minutes of Ischemia in the Gerbil is Preceded by Prolonged Impairment of Protein Metabolism

1992 • 41 citations

Opioid peptide levels in gerbil brain after transient ischemia: lasting depletion of hippocampal dynorphin.

1987 • 39 citations

Focal protein synthesis inhibition in a model of neonatal hypoxic-ischemic brain injury

1987 • 30 citations

Activation of adenosine receptors induces c-fos, but not c-jun, expression in neuron-glia hybrids and fibroblasts

1990 • 21 citations

β‐Adrenergic treatment of C6 glioma cells produces opposite changes in c‐fos and c‐jun mRNA levels

1991 • 10 citations

Dr. August Weismann on the Importance of Sexual Reproduction for the theory of Selection 1

1886 • 6 citations