Asparagine-linked Oligosaccharides Protect Lamp-1 and Lamp-2 from Intracellular Proteolysis

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Biological roles of oligosaccharides: all of the theories are correct

1993 • 5,121 citations

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

The mannose 6-phosphate receptor and the biogenesis of lysosomes

1988 • 846 citations

Rab9 functions in transport between late endosomes and the trans Golgi network.

1993 • 556 citations

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes.

1996 • 531 citations

Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan.

1988 • 335 citations

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network.

1994 • 306 citations

Characterization of protein transport between successive compartments of the Golgi apparatus: Asymmetric properties of donor and acceptor activities in a cell-free system

1985 • 301 citations

Glycoforms modify the dynamic stability and functional activity of an enzyme

1994 • 296 citations

Glycoproteins of the lysosomal membrane.

1985 • 294 citations

Intracellular trafficking of lysosomal membrane proteins

1996 • 277 citations

The unfolded protein response: an intracellular signalling pathway with many surprising features

1998 • 274 citations

Cycling of the integral membrane glycoprotein, LEP100, between plasma membrane and lysosomes: Kinetic and morphological analysis

1987 • 244 citations

Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles

1997 • 234 citations

Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface glycoproteins.

1975 • 227 citations

Fusion of Lysosomes with Late Endosomes Produces a Hybrid Organelle of Intermediate Density and Is NSF Dependent

1998 • 216 citations

Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins.

1986 • 212 citations

Normal Lysosomal Morphology and Function in LAMP-1-deficient Mice

1999 • 187 citations

Cloning of cDNAs encoding human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Comparison of their deduced amino acid sequences.

1988 • 187 citations

Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation

1996 • 170 citations

Purification and characterization of human lysosomal membrane glycoproteins

1989 • 163 citations

Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants.

1989 • 153 citations

Characterization of the signal for rapid internalization of the bovine mannose 6-phosphate/insulin-like growth factor-II receptor.

1992 • 144 citations

Glycosylated and unglycosylated human lactoferrins both bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities towards tryptic proteolysis

1995 • 141 citations

Enrichment of Bis-(monoacylglyceryl) Phosphate in Lysosomes from Rat Liver

1972 • 131 citations

The effect of 1-deoxymannojirimycin on rat liver α-mannosidases

1984 • 127 citations

Isolation of a Clone of Chinese Hamster Ovary Cells Deficient in Plant Lectin-Binding Sites

1974 • 120 citations

Novel stereoconfiguration in lyso-bis-phosphatidic acid of cultured BHK-cells

1974 • 116 citations

The effects of variable glycosylation on the functional activities of ribonuclease, plasminogen and tissue plasminogen activator

1995 • 103 citations

A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells

1997 • 86 citations

A determinant in the cytoplasmic tail of the cation-dependent mannose 6-phosphate receptor prevents trafficking to lysosomes.

1995 • 79 citations

Rab7 and Rab9 Are Recruited onto Late Endosomes by Biochemically Distinguishable Processes

1995 • 78 citations

Supramolecular Assemblies from Lysosomal Matrix Proteins and Complex Lipids

1997 • 20 citations

An arrested late endosome-lysosome intermediate aggregate observed in a Chinese hamster ovary cell mutant isolated by novel three-step screening

1999 • 19 citations

Glycosphingolipids in Secondary Lysosomes Prepared from Rat Liver

1974 • 12 citations

Limited proteolysis of chicken gizzard 5′-nucleotidase

1992 • 4 citations