Remodeling and reparation of the cardiovascular system

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study

1990 • 5,586 citations

Cardiovascular System

2000 • 2,962 citations

Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications.

1990 • 2,864 citations

Relation of Left Ventricular Mass and Geometry to Morbidity and Mortality in Uncomplicated Essential Hypertension

1991 • 2,374 citations

Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.

1977 • 2,105 citations

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Physiological aspects of primary hypertension.

1982 • 1,787 citations

The hibernating myocardium

1989 • 1,256 citations

Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent

1986 • 1,106 citations

Cardiac interstitium in health and disease: The fibrillar collagen network

1989 • 1,044 citations

Hypertension: Pathophysiology, Diagnosis, and Management

1991 • 940 citations

Structure and function of small arteries

1990 • 902 citations

Echocardiographically Detected Left Ventricular Hypertrophy: Prevalence and Risk Factors

1988 • 811 citations

Ventricular Remodeling after Myocardial Infarction

1993 • 752 citations

Association of the Renin-Sodium Profile with the Risk of Myocardial Infarction in Patients with Hypertension

1991 • 734 citations

Evidence for Cardiomyopathy in Familial Diabetes Mellitus

1977 • 718 citations

Exercise training in patients with severe left ventricular dysfunction. Hemodynamic and metabolic effects.

1988 • 701 citations

Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure.

1990 • 693 citations

Remodeling of the rat right and left ventricles in experimental hypertension.

1990 • 676 citations

Cardiomyopathy of Overload

1990 • 566 citations

Cellular Pathology As Based upon Physiological and Pathological Histology.

1972 • 460 citations

Long-term beta-blockade in dilated cardiomyopathy. Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol.

1989 • 447 citations

Angina Due to Coronary Microvascular Disease in Hypertensive Patients without Left Ventricular Hypertrophy

1988 • 434 citations

Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries.

1991 • 411 citations

Anderson's Pathology

1995 • 403 citations

Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanism.

1991 • 397 citations

Contribution of intrinsic skeletal muscle changes to 31P NMR skeletal muscle metabolic abnormalities in patients with chronic heart failure.

1989 • 390 citations

Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart.

1990 • 389 citations

Dynamic state of collagen: pathways of collagen degradation in vivo and their possible role in regulation of collagen mass

1987 • 379 citations

Functional importance of the long axis dynamics of the human left ventricle.

1990 • 362 citations

Endothelin: visualization of mRNAs by in situ hybridization provides evidence for local action.

1989 • 354 citations

The Effect of Weight Reduction on Left Ventricular Mass

1986 • 343 citations

A comparison of the pathological spectrum of hypertensive, diabetic, and hypertensive-diabetic heart disease.

1990 • 338 citations

Cardioreparative effects of lisinopril in rats with genetic hypertension and left ventricular hypertrophy.

1991 • 329 citations

Quantitative structural analysis of the myocardium during physiologic growth and induced cardiac hypertrophy: A review

1986 • 315 citations

Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation--contraction coupling in isolated resistance vessels from essential hypertensives.

1987 • 303 citations

Exercise training in patients with chronic heart failure delays ventilatory anaerobic threshold and improves submaximal exercise performance.

1989 • 291 citations

Increased endothelin in experimental heart failure.

1990 • 288 citations

Altered Myocardial Function and Metabolism in Chronic Diabetes Mellitus without Ischemia in Dogs

1974 • 282 citations

Preclinical abnormality of left ventricular function in diabetes mellitus

1975 • 280 citations

Cellular basis of chronic ventricular remodeling after myocardial infarction in rats.

1991 • 278 citations

Left ventricular shape, afterload and survival in idiopathic dilated cardiomyopathy

1989 • 275 citations

Skeletal muscle metabolism during exercise under ischemic conditions in congestive heart failure. Evidence for abnormalities unrelated to blood flow.

1988 • 273 citations

Dietary salt intake. A determinant of cardiac involvement in essential hypertension.

1988 • 269 citations

RCapillaries: Basement Membrane Thickening by Galactosemia Prevented with Aldose Reductase Inhibitor

1983 • 265 citations

Fibrillar collagen and remodeling of dilated canine left ventricle.

1990 • 264 citations

Cardiac hypertrophy and antihypertensive therapy

1977 • 260 citations

Diabetic cardiomyopathy

1985 • 247 citations

Profound structural alterations of the extracellular collagen matrix in postischemic dysfunctional (“stunned”) but viable myocardium

1987 • 244 citations

Imbalance of Endothelium-derived Relaxing and Contracting Factors: A New Concept in Hypertension?

1990 • 243 citations

Collagen network remodelling and diastolic stiffness of the rat left ventricle with pressure overload hypertrophy

1988 • 243 citations

Relation of blood pressure and body build to left ventricular mass in normotensive and hypertensive employed adults

1988 • 242 citations

Myocyte cell loss and myocyte hypertrophy in the aging rat heart

1986 • 241 citations

Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats.

1987 • 229 citations

Localization of types I, III and IV collagen mRNAs in rat heart cells by in situ hybridization

1989 • 215 citations

Reversibility of left ventricular hypertrophy by differing types of antihypertensive therapy.

1992 • 211 citations

Localization of angiotensin converting enzyme in rat heart.

1991 • 205 citations

Increased expression of basement membrane components in human endothelial cells cultured in high glucose.

1988 • 200 citations

Endothelin-1 is an autocrine/paracrine growth factor for human cancer cell lines.

1991 • 198 citations

Endothelin has biological actions at pathophysiological concentrations.

1991 • 191 citations

Angiotensin converting enzyme in rat brain visualized by quantitative in vitro autoradiography

1987 • 175 citations

Effects of left ventricular shape and captopril therapy on exercise capacity after anterior wall acute myocardial infarction

1989 • 174 citations

Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats

1990 • 174 citations

Whole blood viscosity as a determinant of cardiac hypertrophy in systemic hypertension

1984 • 164 citations

Development of blood pressure in spontaneously hypertensive rats after withdrawal of long-term treatment related to vascular structure

1989 • 163 citations

Epidemiological Aspects of Heart Failure

1989 • 155 citations

β-Adrenergic receptor decrease in diabetic rat hearts

1979 • 147 citations

Left ventricular mass and exercise responses predict future blood pressure. The Muscatine Study.

1988 • 145 citations

1989 Corcoran lecture: adaptive and maladaptive responses of the arterial wall to hypertension.

1990 • 145 citations

Collagen synthesis in development and reversal of cardiac hypertrophy in spontaneously hypertensive rats

1979 • 134 citations

Compared myocardial and vascular effects of captopril and dihydralazine during hypertension development in spontaneously hypertensive rats

1983 • 134 citations

Reducing pulse pressure in hypertension may normalize small artery structure.

1991 • 133 citations

Diabetes-induced abnormalities in the myocardium

1986 • 127 citations

Left ventricular hypertrophy and function in high, normal, and low-renin forms of essential hypertension.

1982 • 125 citations

Echocardiographic features of impaired ventricular function in diabetes mellitus.

1982 • 122 citations

Mineralocorticoid binding in cultured smooth muscle cells and fibroblasts from rat aorta

1981 • 113 citations

Flow restriction of one carotid artery in juvenile rats inhibits growth of arterial diameter

1985 • 112 citations

The myofibroblast: a key cell for wound healing and fibrocontractive diseases.

1981 • 109 citations

Left ventricular mass reduction during salt depletion in arterial hypertension.

1984 • 109 citations

Early 24-hour blood pressure elevation in normotensive subjects with parental hypertension.

1990 • 107 citations

Effects of chronic ACE inhibition on cardiac hypertrophy and coronary vascular reserve in spontaneously hypertensive rats with developed hypertension

1989 • 107 citations

Echocardiographic Left Ventricular Mass and Electrolyte Intake Predict Arterial Hypertension

1991 • 106 citations

Enalapril can prevent vascular amplifier development in spontaneously hypertensive rats.

1990 • 104 citations

Genetic and Environmental Influences on Echocardiographically Determined Left Ventricular Mass in Black Twins

1990 • 97 citations

Cellular basis of wall remodeling in long-term pressure overload-induced right ventricular hypertrophy in rats.

1988 • 86 citations

Hypertensive Heart Disease.

1980 • 84 citations

Hypertensive cardiomyopathy. Myocyte nuclei hyperplasia in the mammalian rat heart.

1990 • 82 citations

Cardiovascular and Renal Effects of Long-term Antihypertensive Treatment

1988 • 79 citations

Delayed effects of early infarct-limiting therapies on healing after myocardial infarction.

1985 • 78 citations

Abnormal structure and function of isolated subcutaneous resistance vessels from essential hypertensive patients despite antihypertensive treatment.

1989 • 76 citations

Cellular hypertrophy in mesenteric resistance vessels from renal hypertensive rats.

1988 • 76 citations

Inhibition of tissue angiotensin converting enzyme. Quantitation by autoradiography.

1988 • 72 citations

Diminished Forearm Arteriolar Dilator Capacity Produced by Mineralocorticoid-Induced Salt Retention in Man

1970 • 72 citations

Left ventricular function and collagen content after regression of hypertensive hypertrophy.

1989 • 70 citations

Development of Microcirculation : Capillary Growth and Adaptation

1984 • 69 citations

Vascular remodeling and improvement of coronary reserve after hydralazine treatment in spontaneously hypertensive rats.

1989 • 69 citations

Reversal of left ventricular hypertrophy by antihypertensive therapy

1982 • 67 citations

Regression of hypertensive left ventricular hypertrophy and left ventricular diastolic function

1990 • 65 citations

Connective Tissue Research — Chemistry, Biology and Physiology

1981 • 62 citations

Reversal of cardiac hypertrophy in renal hypertensive rats: medical vs. surgical therapy

1981 • 61 citations

CHANGES IN CARDIAC ANGIOTENSIN CONVERTING ENZYME AFTER MYOCARDIAL INFARCTION AND HYPERTROPHY IN RATS

1991 • 58 citations

Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure

1990 • 53 citations

Angiotensin Converting Enzyme Inhibition in Heart, Kidney, and Serum Studied Ex Vivo after Administration of Zofenopril, Captopril, and Lisinopril

1991 • 51 citations

LOCALIZATION OF ANGIOTENSIN CONVERTING ENZYME IN RAT FOREBRAIN AND OTHER TISSUES BY IN VITRO AUTORADIOGRAPHY USING ¹²⁵‐I‐LABELLED MK351A

1984 • 51 citations

Measurement of angiotensin converting enzyme induction and inhibition using quantitative in vitro autoradiography: tissue selective induction after chronic lisinopril treatment

1991 • 50 citations

Purification and large-scale preparation of antithrombin III

1989 • 48 citations

Relationship between ambulatory or exercise blood pressure and left ventricular structure: prognostic implications.

1990 • 46 citations

Characterization of cardiac angiotensin converting enzyme (ACE) and in vivo inhibition following oral quinapril to rats

1990 • 40 citations

Long-term effects of xamoterol on left ventricular diastolic function and late remodeling: a study in patients with anterior myocardial infarction and single-vessel disease.

1988 • 40 citations

Overview of hemodynamic and non-hemodynamic factors associated with left ventricular hypertrophy

1989 • 39 citations

Myocardial disease in hypertensive-diabetic patients

1989 • 37 citations

Depressed aerobic enzyme activity of skeletal muscle in severe chronic heart failure.

1991 • 33 citations

Adaptive changes in the periphery and their therapeutic consequences

1991 • 31 citations

Echocardiographic Left Ventricular Hypertrophy in Hypertension

1983 • 31 citations

Nonischemic myocardial damage induced by nonocclusive constriction of coronary artery in rats

1991 • 27 citations

Collagen metabolism during right ventricular hypertrophy following induced lung injury

1986 • 26 citations

Coronary Circulation in Arterial Hypertension

1991 • 24 citations

Diabetes-induced alterations in atrial natriuretic peptide gene expression in Wistar-Kyoto and spontaneously hypertensive rats.

1990 • 21 citations

The effect of streptozotocin-induced diabetes and insulin treatment on angiotensin converting enzyme activity.

1987 • 20 citations

Cardiac volume load as a determinant of the response of cardiac mass to antihypertensive therapy

1990 • 19 citations

Cellular morphology in mesenteric resistance vessels from antihypertensive treated spontaneously hypertensive rats.

1991 • 18 citations

Vascular Effects of ACE Inhibition by Perindopril

1990 • 15 citations

Time Course of Development of Changes in the Structure and Reactivity of Small Veins from Portal Hypertensive Rabbits

1989 • 14 citations

ABNORMALITIES OF RESISTANCE VESSEL STRUCTURE IN ESSENTIAL HYPERTENSION: ARE THESE IMPORTANT?

1991 • 12 citations

Hypertension as a vascular response to injury.

1984 • 11 citations

Vascular and adrenal reninlike activity in chronically diabetic rats.

1988 • 10 citations

Influence of left ventricular mass regression on cardiac function in hypertensive elderly individuals

1990 • 10 citations

Hypertensive Heart Disease

2017 • 4 citations

The Severity of Diabetes is a Major Determinant of Myocardial Damage in the Rat

1991 • 3 citations