Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

CTLA-4 is a second receptor for the B cell activation antigen B7.

1991 • 1,662 citations

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1992 • 1,573 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1992 • 1,290 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro.

1994 • 607 citations

Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation.

1993 • 569 citations

Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.

1994 • 379 citations

CD28 costimulation inhibits TCR-induced apoptosis during a primary T cell response.

1996 • 198 citations

B7-1 expression of Langerhans cells is up-regulated by proinflammatory cytokines, and is down-regulated by interferon-γ or by interleukin-10

1995 • 175 citations

Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells.

1997 • 170 citations

The Role of B7-1/B7-2:CD28/CLTA-4 Pathways in the Prevention of Anergy, Induction of Productive Immunity and Down-Regulation of the Immune Response

1996 • 161 citations

Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation.

1996 • 160 citations

Does B7-1 expression confer antigen-presenting cell capacity to tumors in vivo?

1996 • 147 citations

Dendritic cells and tolerance induction

1996 • 128 citations

Interaction between two cellular subpopulations of a rat colonic carcinoma when inoculated to the syngeneic host

1985 • 119 citations

In situ expression of B7 and CD28 receptor families in human malignant melanoma: Relevance for T‐cell‐mediated anti‐tumor immunity

1995 • 57 citations

Tumor-rejection antigens recognized by T lymphocytes

1993 • 45 citations

Surface phenotype and functions of tumor‐infiltrating dendritic cells: CD8 expression by a cell subpopulation

1993 • 42 citations

Specificity of the immune response leading to protection or enhancement by regressive and progressive variants of a rat colon carcinoma

1988 • 38 citations

The primary alloresponse of human CD4⁺ T cells is dependent on B7 (CD80), augmented by CD58, but relatively uninfluenced by CD54 expression

1995 • 33 citations

T-cell co-stimulation by the CD28 ligand B7 is involved in the immune response leading to rejection of a spontaneously regressive tumor

1996 • 15 citations