p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

X-linked IAP is a direct inhibitor of cell-death proteases

1997 • 1,961 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53

1990 • 1,796 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Control of adhesion-dependent cell survival by focal adhesion kinase.

1996 • 1,113 citations

p53 functions as a cell cycle control protein in osteosarcomas.

1990 • 774 citations

The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression.

1995 • 627 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis.

1996 • 371 citations

Cleavage of Focal Adhesion Kinase by Caspases during Apoptosis

1997 • 338 citations

UV activates growth factor receptors via reactive oxygen intermediates.

1996 • 281 citations

Fibronectin is a survival factor for differentiated osteoblasts

1998 • 259 citations

Ordering the Cell Death Pathway

1996 • 231 citations

Decreased Egr-1 expression in human, mouse and rat mammary cells and tissues correlates with tumor formation

1997 • 229 citations

p53 Functions as a Cell Cycle Control Protein in Osteosarcomas

1990 • 224 citations

Essential role for p53-mediated transcription in E1A-induced apoptosis.

1995 • 219 citations

Cleavage of CDK Inhibitor p21Cip1/Waf1 by Caspases Is an Early Event during DNA Damage-induced Apoptosis

1998 • 215 citations

SAGE transcript profiles for p53-dependent growth regulation

1997 • 182 citations

Radiation induction of immediate early genes: Effectors of the radiation-stress response

1994 • 174 citations

Early Growth Response-1-dependent Apoptosis Is Mediated by p53

1997 • 172 citations

Differential Regulation of the p21/WAF-1 and mdm2 Genes after High-Dose UV Irradiation: p53-Dependent and p53-Independent Regulation of the mdm2 Gene

1997 • 172 citations

Induction of Apoptosis after Expression of PYK2, a Tyrosine Kinase Structurally Related to Focal Adhesion Kinase

1997 • 167 citations

Transcription factor EGR-1 suppresses the growth and transformation of human HT-1080 fibrosarcoma cells by induction of transforming growth factor beta 1.

1996 • 155 citations

Egr-1 negatively regulates human tumor cell growth via the DNA-binding domain.

1995 • 145 citations

p53-dependent DNA damage-induced apoptosis requires Fas/APO-1-independent activation of CPP32beta.

1997 • 130 citations

Tumor-suppressor p53 and the cell cycle

1993 • 120 citations

The Transcription Factor EGR-1 Suppresses Transformation of Human Fibrosarcoma HT1080 Cells by Coordinated Induction of Transforming Growth Factor-β1, Fibronectin, and Plasminogen Activator Inhibitor-1

1999 • 111 citations

Binding of urokinase to plasminogen activator inhibitor type-1 mediates cell adhesion and spreading

1997 • 107 citations

Role of EGR-1 in Thapsigargin-Inducible Apoptosis in the Melanoma Cell Line A375-C6

1995 • 107 citations

c-jun and Egr-1 Participate in DNA Synthesis and Cell Survival in Response to Ionizing Radiation Exposure

1995 • 106 citations

E1a induces the expression of epithelial characteristics.

1994 • 106 citations

Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1

1997 • 86 citations

Fibronectin Suppresses Apoptosis in Normal Human Melanocytes Through an Integrin-Dependent Mechanism

1997 • 82 citations

EGR-1 Induction Is Required for Maximal Radiosensitivity in A375-C6 Melanoma Cells

1996 • 69 citations

Egr-1 inhibits apoptosis during the UV response: correlation of cell survival with Egr-1 phosphorylation

1998 • 68 citations

Caspase 3 specifically cleaves p21^WAF1/CIP1 in the earlier stage of apoptosis in SK‐HEP‐1 human hepatoma cells

1998 • 67 citations

Suppression of transformed phenotypes of human fibrosarcoma cells by overexpression of recombinant fibronectin.

1996 • 54 citations

Transcription factor Egr-1 activity down-regulates Fas and CD23 expression in B cells.

1997 • 49 citations

Protein kinase C-zeta reverts v-raf transformation of NIH-3T3 cells.

1996 • 43 citations

Suppression of human fibrosarcoma cell growth by transcription factor, Egr-1, involves down-regulation of Bcl-2

1998 • 40 citations

Role of Egr-1 Gene Expression in B Cell Receptor-induced Apoptosis in an Immature B Cell Lymphoma

1997 • 37 citations

Inhibition of Cell Growth by Transforming Growth Factor β1 Is Associated with p53‐Independent Induction of p21 in Gastric Carcinoma Cells

1996 • 34 citations

Functions of the p53 Protein in Growth Regulation and Tumor Suppression

1994 • 32 citations

Lasers In Endonasal Surgery

1997 • 31 citations

Modifications of p53 Protein and Accumulation of p21 and gadd45 mRNA in TGF-β1 Growth Inhibited Cells

1997 • 30 citations

Reversal of malignancy by the adenovirus E1a gene

1996 • 15 citations

V‐sis induces Egr‐1 expression by a pathway mediated by c‐Ha‐ras

1994 • 13 citations

On the non-compactness of the core of nonatomic convexσ-continuous measure games

1995 • 1 citations