EGR-1 Induction Is Required for Maximal Radiosensitivity in A375-C6 Melanoma Cells

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1992 • 3,092 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

1988 • 1,278 citations

Early Growth Response Protein 1 (Egr-1): Prototype of a Zinc-finger Family of Transcription Factors

1995 • 593 citations

p53 mutations increase resistance to ionizing radiation.

1993 • 573 citations

Apoptosis-the molecular basis of cell death

1992 • 517 citations

Transcriptional Repression Mediated by the WT1 Wilms Tumor Gene Product

1991 • 492 citations

In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors

1988 • 462 citations

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors.

1995 • 421 citations

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

1993 • 384 citations

NAB2, a Corepressor of NGFI-A (Egr-1) and Krox20, Is Induced by Proliferative and Differentiative Stimuli

1996 • 353 citations

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

1991 • 277 citations

Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription.

1995 • 258 citations

Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.

1985 • 174 citations

Role of EGR-1 in Thapsigargin-Inducible Apoptosis in the Melanoma Cell Line A375-C6

1995 • 107 citations

A biological role for Egr-1 in cell survival following ultra-violet irradiation.

1995 • 57 citations

cDNA sequence of the human cellular early growth response gene Egr-1

1990 • 51 citations

The Zinc Finger Transcription Factor EGR-1 Impedes Interleukin-1-Inducible Tumor Growth Arrest

1995 • 41 citations

Interleukin-1-inducible tumor growth arrest is characterized by activation of cell type-specific “early” gene expression programs.

1992 • 33 citations