E2F1 and E1A(12S) have a homologous activation domain regulated by RB and CBP.

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

1993 • 960 citations

Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties

1992 • 846 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F

1992 • 652 citations

Adenoviral ElA-associated protein p300 as a functional homologue of the transcriptional co-activator CBP

1995 • 578 citations

A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

1995 • 534 citations

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein.

1993 • 460 citations

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

1995 • 459 citations

Identification of a growth suppression domain within the retinoblastoma gene product.

1992 • 413 citations

E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product.

1993 • 353 citations

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

1994 • 256 citations

Identification of specific adenovirus E1A N-terminal residues critical to the binding of cellular proteins and to the control of cell growth

1993 • 254 citations

DNA tumor virus transforming proteins and the cell cycle

1993 • 242 citations

DP and E2F proteins: coordinating transcription with cell cycle progression

1994 • 205 citations

Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes.

1991 • 161 citations

Inhibition of E2F-1 Transactivation by Direct Binding of the Retinoblastoma Protein

1993 • 151 citations

p53-mediated apoptosis in HeLa cells can be overcome by excess pRB.

1995 • 136 citations

The retinoblastoma protein binds E2F residues required for activation in vivo and TBP bindingin vitro

1993 • 131 citations

Conserved motifs in Fos and Jun define a new class of activation domain.

1992 • 120 citations

Adenovirus E1A makes two distinct contacts with the retinoblastoma protein

1992 • 113 citations

Identification of distinct roles for separate E1A domains in disruption of E2F complexes.

1993 • 113 citations

Functional interactions within adenovirus E1A protein complexes.

1994 • 100 citations

Differential Effects of the Adenovirus E1A Oncogene on Members of the AP-1 Transcription Factor Family

1990 • 83 citations

Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains.

1992 • 73 citations

E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activity

1995 • 64 citations

Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters

1994 • 42 citations

An adenovirus E1A transcriptional repressor domain functions as an activator when tethered to a promoter

1994 • 37 citations

Promoter-Specific Zrans-Activation by the Adenovirus E1A_12S Product Involves Separate E1A Domains

1992 • 25 citations