Regulation of expression of contractile proteins with cardiac hypertrophy and failure

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

Developmental and functional adaptation of contractile proteins in cardiac and skeletal muscles

1986 • 657 citations

Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response.

1983 • 618 citations

Expression of the cardiac ventricular alpha- and beta-myosin heavy chain genes is developmentally and hormonally regulated.

1984 • 609 citations

Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals.

1987 • 445 citations

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

1988 • 425 citations

Transcripts of α-cardiac and α-skeletal actins are early markers for myogenesis in the mouse embryo

1988 • 330 citations

Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene.

1994 • 310 citations

Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches.

1989 • 308 citations

Alpha-skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts.

1986 • 282 citations

Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.

1991 • 228 citations

Nucleotide sequence of the rat skeletal muscle actin gene

1982 • 207 citations

Regulation of myosin heavy chain genes in the heart.

1993 • 203 citations

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes.

1987 • 201 citations

The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes.

1990 • 200 citations

Developmental and hormonal regulation of sarcomeric myosin heavy chain gene family.

1987 • 200 citations

M-CAT, CArG, and Sp1 Elements Are Required for α1-Adrenergic Induction of the Skeletal α-Actin Promoter during Cardiac Myocyte Hypertrophy

1995 • 181 citations

A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells.

1991 • 175 citations

Expression of the genes coding for the skeletal muscle and cardiac actins in the heart

1984 • 157 citations

An enhancer core element mediates stimulation of the rat beta-myosin heavy chain promoter by an alpha 1-adrenergic agonist and activated beta-protein kinase C in hypertrophy of cardiac myocytes.

1994 • 146 citations

Alpha 1-adrenergic receptor stimulation of sarcomeric actin isogene transcription in hypertrophy of cultured rat heart muscle cells.

1989 • 138 citations

Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo.

1993 • 132 citations

Alpha-skeletal actin is associated with increased contractility in the mouse heart.

1994 • 128 citations

Regulation of myosin synthesis by thyroid hormone: relative change in the .alpha.- and .beta.-myosin heavy chain mRNA levels in rabbit heart

1984 • 128 citations

Coexpression of α-sarcomeric actin, α-smooth muscle actin and desmin during myogenesis in rat and mouse embryos I. Skeletal muscle

1990 • 126 citations

Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.

1991 • 124 citations

Adrenergic regulation of the skeletal alpha-actin gene promoter during myocardial cell hypertrophy.

1991 • 110 citations

Transcriptional enhancer factor-1 in cardiac myocytes interacts with an alpha 1-adrenergic- and beta-protein kinase C-inducible element in the rat beta-myosin heavy chain promoter.

1993 • 103 citations

Cardiac expressions of alpha- and beta-myosin heavy chains and sarcomeric alpha-actins are regulated through transcriptional mechanisms. Results from nuclear run-on assays in isolated rat cardiac nuclei.

1992 • 101 citations

Interaction of thyroid hormone receptors with strong and weak cis-acting elements in the human alpha-myosin heavy chain gene promoter.

1990 • 98 citations

Changes in myosin isoenzymes, ATPase activity, and contraction duration in rat cardiac muscle with aging can be modulated by thyroxine.

1987 • 95 citations

Transgenic analysis of the thyroid-responsive elements in the alpha-cardiac myosin heavy chain gene promoter.

1993 • 93 citations

Characterization of a strong positive cis-acting element of the human beta-myosin heavy chain gene in fetal rat heart cells.

1992 • 87 citations

Positive regulation of the skeletal alpha-actin gene by Fos and Jun in cardiac myocytes.

1992 • 86 citations

Expression of the sarcomeric actin isogenes in the rat heart with development and senescence.

1992 • 82 citations

Practical aspects of radio-isotopic in situ hybridization on RNA

1993 • 79 citations

An E-box/M-CAT hybrid motif and cognate binding protein(s) regulate the basal muscle-specific and cAMP-inducible expression of the rat cardiac alpha-myosin heavy chain gene.

1994 • 74 citations

The development expression of the rat alpha-vascular and gamma-enteric smooth muscle isoactins: isolation and characterization of a rat gamma-enteric actin cDNA.

1988 • 67 citations

Transcription Factor GATA-4 Regulates Cardiac Muscle-Specific Expression of the α-Myosin Heavy-Chain Gene

1994 • 64 citations

Clenbuterol Induces Hypertrophy of the Latissimus Dorsi Muscle and Heart in the Rat With Molecular and Phenotypic Changes

1995 • 61 citations

Effect of thyroid hormone on the accumulation of mRNA for skeletal and cardiac alpha-actin in hearts from normal and hypophysectomized rats.

1990 • 60 citations

Myosin isozyme synthesis and mRNA levels in pressure-overloaded rabbit hearts.

1987 • 60 citations

An M-CAT Binding Factor and an RSRF-Related A-Rich Binding Factor Positively Regulate Expression of the α-Cardiac Myosin Heavy-Chain Gene In Vivo

1994 • 59 citations

Distinct behavior of cardiac myosin heavy chain gene constructs in vivo. Discordance with in vitro results.

1993 • 58 citations

Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway.

1992 • 45 citations

Molecular biology of muscle

1992 • 40 citations

Plasticity of the Myocardium Generated through Protein Isoform Switches

1989 • 39 citations

The human skeletal alpha-actin promoter is regulated by thyroid hormone: identification of a thyroid hormone response element.

1992 • 23 citations

Regulation of myosin heavy chain and actin isogenes during cardiac growth and hypertrophy.

1992 • 19 citations

Regulation of myosin heavy chain and actin isogenes expression during cardiac growth

1991 • 19 citations

The Development Expression of the Rat α-Vascular and ϒ-Enteric Smooth Muscle Isoactins: Isolation and Characterization of a Rat ϒ-Enteric Actin cDNA

1988 • 16 citations

Characterization of a Novel Transcript of Retroviral Origin Expressed in Rat Heart and Liver

1995 • 9 citations