Cardiac expressions of alpha- and beta-myosin heavy chains and sarcomeric alpha-actins are regulated through transcriptional mechanisms. Results from nuclear run-on assays in isolated rat cardiac nuclei.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

ATPase Activity of Myosin Correlated with Speed of Muscle Shortening

1967 • 1,969 citations

Electrophoretic analysis of multiple forms of rat cardiac myosin: Effects of hypophysectomy and thyroxine replacement

1978 • 772 citations

Expression of the cardiac ventricular alpha- and beta-myosin heavy chain genes is developmentally and hormonally regulated.

1984 • 609 citations

THE ROLE OF ANTISENSE RNA IN GENE REGULATION

1986 • 456 citations

Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals.

1987 • 445 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

Thyroid hormone receptor α isoforms generated by alternative splicing differentially activate myosin HC gene transcription

1988 • 425 citations

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

1990 • 334 citations

Transcripts of α-cardiac and α-skeletal actins are early markers for myogenesis in the mouse embryo

1988 • 330 citations

Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches.

1989 • 308 citations

An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes

1989 • 305 citations

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA

1982 • 295 citations

Alpha-skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts.

1986 • 282 citations

Increased myothermal economy of isometric force generation in compensated cardiac hypertrophy induced by pulmonary artery constriction in the rabbit. A characterization of heat liberation in normal and hypertrophied right ventricular papillary muscles.

1982 • 254 citations

Cellular and molecular biology of muscle development

1990 • 248 citations

α-Skeletal and α-Cardiac Actin Genes Are Coexpressed in Adult Human Skeletal Muscle and Heart

1983 • 237 citations

Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.

1991 • 228 citations

Simultaneous expression of skeletal muscle and heart actin proteins in various striated muscle tissues and cells. A quantitative determination of the two actin isoforms.

1986 • 225 citations

Nucleotide sequence of the rat skeletal muscle actin gene

1982 • 207 citations

Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes.

1987 • 201 citations

The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes.

1990 • 200 citations

Alpha 1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells. Effects on myosin light chain-2 gene expression.

1988 • 185 citations

The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor.

1989 • 166 citations

Expression of the genes coding for the skeletal muscle and cardiac actins in the heart

1984 • 157 citations

Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload--induced cardiac hypertrophy demonstrated by in situ hybridization.

1989 • 154 citations

Nonenzymatic separation of myocardial cell nuclei from whole heart tissue

1983 • 146 citations

Actin and myosin multigene families: their expression during the formation of skeletal muscle.

1985 • 142 citations

Alpha 1-adrenergic receptor stimulation of sarcomeric actin isogene transcription in hypertrophy of cultured rat heart muscle cells.

1989 • 138 citations

Regulation of myosin synthesis by thyroid hormone: relative change in the .alpha.- and .beta.-myosin heavy chain mRNA levels in rabbit heart

1984 • 128 citations

Skeletal actin mRNA increases in the human heart during ontogenic development and is the major isoform of control and failing adult hearts.

1991 • 124 citations

Adrenergic regulation of the skeletal alpha-actin gene promoter during myocardial cell hypertrophy.

1991 • 110 citations

Changes in Gene Expression during Cardiac Growth

1991 • 95 citations

Changes in myosin isoenzymes, ATPase activity, and contraction duration in rat cardiac muscle with aging can be modulated by thyroxine.

1987 • 95 citations

Transcription of early developmental isogenes in cardiac myocyte hypertrophy

1989 • 94 citations

Interaction of Nuclear Proteins with Muscle-Specific Regulatory Sequences of the Human Cardiac α-Actin Promoter

1988 • 93 citations

CArG boxes in the human cardiac alpha-actin gene are core binding sites for positive trans-acting regulatory factors.

1987 • 84 citations

Differentiation, not determination, regulates muscle gene activation: transfection of troponin I genes into multipotential and muscle lineages of 10T1/2 cells.

1985 • 77 citations

Proliferating cell nuclear antigen in developing and adult rat cardiac muscle cells.

1991 • 63 citations

Myosin isozyme synthesis and mRNA levels in pressure-overloaded rabbit hearts.

1987 • 60 citations

Effect of thyroid hormone on the accumulation of mRNA for skeletal and cardiac alpha-actin in hearts from normal and hypophysectomized rats.

1990 • 60 citations

Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line

1990 • 39 citations

Identification and Characterization of a Factor That Binds to Two Human Sarcomeric Actin Promoters

1989 • 34 citations

Measurements of atmospheric BrOx radicals in the tropical and mid-latitude atmosphere

1988 • 32 citations

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line

1991 • 25 citations

Differential co-expression of α-actin genes within the human heart

1986 • 20 citations

Regulation of myosin heavy chain and actin isogenes expression during cardiac growth

1991 • 19 citations

Transcription and Translation

2007 • 17 citations

RNA transcription in myocardial-cell nuclei during postnatal development. A study establishing an assay system for transcription in vitro

1988 • 13 citations