Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation

1990 • 1,332 citations

Effect of pressure development on oxygen consumption by isolated rat heart

1967 • 1,099 citations

Targetted correction of a mutant HPRT gene in mouse embryonic stem cells

1987 • 786 citations

Electrophoretic analysis of multiple forms of rat cardiac myosin: Effects of hypophysectomy and thyroxine replacement

1978 • 772 citations

Developmental and functional adaptation of contractile proteins in cardiac and skeletal muscles

1986 • 657 citations

All Members of the MHC Multigene Family Respond to Thyroid Hormone in a Highly Tissue-Specific Manner

1986 • 632 citations

Expression of the cardiac ventricular alpha- and beta-myosin heavy chain genes is developmentally and hormonally regulated.

1984 • 609 citations

The new mouse genetics: Altering the genome by gene targeting

1989 • 608 citations

Myosin isoenzyme redistribution in chronic heart overload

1979 • 524 citations

Developmental regulation of myosin gene expression in mouse cardiac muscle.

1990 • 408 citations

Myosin isoenzymic distribution correlates with speed of myocardial contraction

1981 • 357 citations

Species- and age-dependent changes in the relative amounts of cardiac myosin isoenzymes in mammals

1981 • 354 citations

Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches.

1989 • 308 citations

Germ-Line Transmission of a c- abl Mutation Produced by Targeted Gene Disruption in ES Cells

1989 • 285 citations

Biochemical and physiologic effects of thyroid hormone on cardiac performance

1983 • 229 citations

A molecular basis for familial hypertrophic cardiomyopathy: An αβ cardiac myosin heavy chain hybrid gene

1990 • 221 citations

Mouse embryonic stem cells express the cardiac myosin heavy chain genes during development in vitro.

1990 • 175 citations

Regulation of myosin isoenzyme composition in fetal and neonatal rat ventricle by endogenous thyroid hormones.

1984 • 170 citations

Isolation and characterization of two molecular variants of myosin heavy chain from rabbit ventricle. Change in their content during normal growth and after treatment with thyroid hormone.

1982 • 144 citations

Alterations of mechanical parameters in chemically skinned preparations of rat myocardium as a function of isoenzyme pattern of myosin

1982 • 140 citations

Characterization of sarcomeric myosin heavy chain genes.

1983 • 136 citations

The chicken myosin heavy chain family.

1986 • 119 citations

Sarcomeric myosin heavy chain gene family: organization and pattern of expression

1986 • 105 citations

Characterization of human cardiac myosin heavy chain genes.

1989 • 101 citations

Isozymic changes in myosin of human atrial myocardium induced by overload. Immunohistochemical study using monoclonal antibodies.

1984 • 85 citations

Molecular cloning and characterization of human cardiac alpha- and beta-form myosin heavy chain complementary DNA clones. Regulation of expression during development and pressure overload in human atrium.

1988 • 82 citations

Alpha-myosin heavy chain isoform and atrial size in patients with various types of mitral valve dysfunction: A quantitative study

1987 • 78 citations

Isolation of multiple genomic sequences coding for chicken myosin heavy chain protein.

1982 • 73 citations

Isolated Heart Preparations Perfused or Superfused with Balanced Salt Solutions

1984 • 32 citations

The developmentally regulated expression of two linked myosin heavy-chain genes

1987 • 29 citations

The structure of two fast-white myosin heavy chain promoters. A comparative study.

1985 • 28 citations

Construction and characterization of the alpha form of a cardiac myosin heavy chain cDNA clone and its developmental expression in the Syrian hamster.

1986 • 18 citations

The inhomogeneity and appropriateness of the myocardial response to stress.

1984 • 12 citations

Differential regulation by thyroid hormones of myosin heavy chain α and β mRNAs in the rat ventricular myocardium

1989 • 9 citations

α-Myosin heavy chain cDNA structure and gene expression in adult, fetal, and premature baboon myocardium

1989 • 8 citations

Heart rate and paired ventricular stimulation: effects on contractile force and K+ exchange

1967 • 8 citations

Histochemical and biochemical analysis of myosin heavy chain expression during cardiogenesis in the rat

1990 • 4 citations

Derived Indices of Myocardial Function in Isolated Work-Performing Hearts

1984 • 4 citations