Inflammation and Atrophy Precede Prostatic Neoplasia in a PhIP-Induced Rat Model

Proliferative Inflammatory Atrophy of the Prostate

1999 • 868 citations

Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee

2004 • 582 citations

The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.

1997 • 392 citations

Functional Epigenomics Identifies Genes Frequently Silenced in Prostate Cancer

2005 • 286 citations

INCIDENCE OF ADENOCARCINOMA OF THE PROSTATE IN ASIAN IMMIGRANTS TO THE UNITED STATES AND THEIR DESCENDANTS

1999 • 234 citations

A Prospective Study of Meat and Meat Mutagens and Prostate Cancer Risk

2005 • 193 citations

Prostatic Intraepithelial Neoplasia in Genetically Engineered Mice

2002 • 170 citations

Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.

2001 • 148 citations

The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention

2001 • 121 citations

Effect of Dietary Constituents With Chemopreventive Potential on Adduct Formation of a Low Dose of the Heterocyclic Amines PhIP and IQ and Phase II Hepatic Enzymes

2003 • 96 citations

The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity

2004 • 91 citations

U.S. dietary exposures to heterocyclic amines*

2001 • 84 citations

Diet and prostate cancer

2002 • 78 citations

Histogenesis and morphology of naturally occurring prostatic carcinoma in the ACI/segHapBR rat.

1980 • 76 citations

Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis

2001 • 75 citations

Prostate mutations in rats induced by the suspected human carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

2000 • 74 citations

Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma.

2003 • 74 citations

Molecular and genetic toxicology of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

2002 • 71 citations

Prostatic hyperplasia and neoplasia in aging F344 rats

1981 • 64 citations

Atrophy and Proliferation in the Young Adult Prostate

1987 • 60 citations

Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat prostate and induction of invasive carcinomas by subsequent treatment with testosterone propionate

1999 • 53 citations

Tea as a Potential Chemopreventive Agent in PhIP Carcinogenesis: Effects of Green Tea and Black Tea on PhIP-DNA Adduct Formation in Female F-344 Rats

2000 • 45 citations

Inflammation-proliferation: possible relationships in the prostate.

1987 • 36 citations

Carcinogenicity of the N-hydroxy derivative of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-amino-3,8-dimethyl-imidazo[4,5-f]quinoxaline and 3,2′-dimethyl-4-aminobiphenyl in the rat

2000 • 31 citations

High susceptibility of the ACI and spontaneously hypertensive rat (SHR) strains to 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine (PhIP) prostate carcinogenesis

2003 • 17 citations

Abnormalities of apoptotic and cell cycle regulatory proteins in distinct histopathologic components of benign prostatic hyperplasia

2004 • 17 citations

On the occurrence of Leydig cell tumors in the F344 rat

2002 • 7 citations