Carcinogenicity of the N-hydroxy derivative of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 2-amino-3,8-dimethyl-imidazo[4,5-f]quinoxaline and 3,2′-dimethyl-4-aminobiphenyl in the rat

The prostate: a target for carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) derived from cooked foods.

1997 • 392 citations

Epidemiology of Bladder Cancer

1992 • 297 citations

Carcinogenicity in rats of a mutagenic compound, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline

1988 • 141 citations

Nutrient Intake in Relation to Bladder Cancer among Middle-aged Men and Women

1996 • 141 citations

Induction of mammary tumors in female Sprague—Dawley rats by the food-derived carcinogen 2-amino-1-methyl-6-phenyliniidazo [4,5-b]pyridine and effect of dietary fat

1994 • 122 citations

Health risks of heterocyclic amines

1997 • 114 citations

Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats

1995 • 96 citations

Carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the rat

1997 • 92 citations

Biochemical Individuality and Its Implications for Drug and Carcinogen Metabolism: Recent Insights from Acetyltransferase and Cytochrome P4501a2 Phenotyping and Genotyping in Humans

1994 • 81 citations

Histogenesis and morphology of naturally occurring prostatic carcinoma in the ACI/segHapBR rat.

1980 • 76 citations

Induction of prostate carcinoma in situ at high incidence in F344 rats by a combination of 3,2'-dimethyl-4-aminobiphenyl and ethinyl estradiol.

1986 • 69 citations

N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium

1999 • 65 citations

Immunohistochemical demonstration of carcinogen-DNA adducts in tissues of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): detection in paraffin-embedded sections and tissue distribution.

1998 • 48 citations

Role of acetyltransferases in the metabolism and carcinogenicity of aromatic amines

1997 • 46 citations

Different carcinogenic responses in a variety of organs, including the prostate, of five different rat strains given 3,2′-dimethyl-4-aminobiphenyl

1990 • 43 citations

In vivo human metabolism of [2-14C]2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

1999 • 25 citations

The Rat Urinary Bladder as a New Target of Heterocyclic Amine Carcinogenicity: Tumor Induction by 3‐Amino‐l‐methyl‐5H‐pyrido[4,3‐β]indole Acetate

1993 • 23 citations

Dose Dependence of N‐Hydroxy‐3,2′‐dimethyM‐aminobiphenyl‐induced Rat Prostate Carcinogenesis

1992 • 7 citations

Selective Induction of Prostate Carcinomas in F344 Rats Treated with Intraperitoneal Injections of N‐Hydroxy‐3,2′‐dimethyl‐4‐aminobiphenyl

1990 • 5 citations

Trial to Induce Prostatic Cancer in ACI/Seg Rats Treated with a Combination of 3,2′‐Dimethyl‐4‐aminobiphenyl and Ethinyl Estradiol

1991 • 4 citations