Differential susceptibility of plasma proteins to oxidative modification: Examination by western blot immunoassay

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Beyond Cholesterol

1989 • 6,533 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

[49] Determination of carbonyl content in oxidatively modified proteins

1990 • 5,654 citations

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Protein Oxidation and Aging

1992 • 2,687 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Protein damage and degradation by oxygen radicals. I. general aspects.

1987 • 1,618 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences

1990 • 1,143 citations

Metal-catalyzed oxidation of proteins. Physiological consequences

1991 • 877 citations

Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation

1990 • 869 citations

Protein damage and degradation by oxygen radicals. II. Modification of amino acids.

1987 • 840 citations

Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury

1988 • 794 citations

Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.

1990 • 787 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis

1990 • 741 citations

Endogenous Oxidative DNA Damage, Aging, and Cancer

1989 • 711 citations

Oxidative damage to DNA: relation to species metabolic rate and life span.

1988 • 587 citations

Protein damage and degradation by oxygen radicals. III. Modification of secondary and tertiary structure.

1987 • 572 citations

Conversion of Amino Acid Residues in Proteins and Amino Acid Homopolymers to Carbonyl Derivatives by Metal-catalyzed Oxidation Reactions

1989 • 488 citations

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1993 • 486 citations

Protein damage and degradation by oxygen radicals. IV. Degradation of denatured protein.

1987 • 482 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing

1983 • 467 citations

Oxygen free radical involvement in ischemia and reperfusion injury to brain

1988 • 429 citations

Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain.

1989 • 409 citations

Protein oxidation and proteolysis during aging and oxidative stress

1989 • 396 citations

The Role of Oxidized Low-Density Lipoproteins in the Pathogenesis of Atherosclerosis

1992 • 386 citations

Oxidative modification of glutamine synthetase. I. Inactivation is due to loss of one histidine residue.

1983 • 367 citations

Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysis.

1981 • 347 citations

Fragmentation of proteins by free radicals and its effect on their susceptibility to enzymic hydrolysis

1986 • 345 citations

Free Radicals in Medicine. II. Involvement in Human Disease

1988 • 344 citations

On the cytotoxicity of vitamin C and metal ions

1983 • 328 citations

Fenton chemistry. Amino acid oxidation.

1991 • 290 citations

Oxidation of proteins by mixed-function oxidation systems: implication in protein turnover, ageing and neutrophil function

1986 • 290 citations

Preferential degradation of the oxidatively modified form of glutamine synthetase by intracellular mammalian proteases.

1985 • 282 citations

Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation

1992 • 279 citations

Oxidants, inflammation, and anti‐inflammatory drugs

1988 • 267 citations

Long-lived reactive species on free-radical-damaged proteins

1992 • 224 citations

Dityrosine and tyrosine oxidation products are endogenous markers for the selective proteolysis of oxidatively modified red blood cell hemoglobin by (the 19 S) proteasome.

1993 • 197 citations

Generation of hybridomas secreting murine reaginic antibodies of anti-DNP specificity.

1980 • 176 citations

Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation.

1985 • 175 citations

The analogous mechanisms of enzymatic inactivation induced by ascorbate and superoxide in the presence of copper.

1983 • 165 citations

The biochemistry of methionine sulfoxide residues in proteins

1982 • 164 citations

Increased carbonyl content of proteins in synovial fluid from patients with rheumatoid arthritis.

1989 • 143 citations

Oxidation state of tissue thiol groups and content of protein carbonyl groups in chickens with inherited muscular dystrophy

1989 • 130 citations

Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: A hypothesis

1990 • 122 citations

Metal-catalyzed oxidation of Escherichia coli glutamine synthetase: Correlation of structural and functional changes

1990 • 121 citations

Interaction of human .alpha.-1-proteinase inhibitor with neutrophil myeloperoxidase

1981 • 119 citations

Inactivation of enzymes and oxidative modification of proteins by stimulated neutrophils

1987 • 111 citations

Hemostasis and Thrombosis in the Clinical Laboratory

1988 • 33 citations

Oxygen radical induced alterations in polyclonal IgG

1988 • 20 citations

Oxidized fibrin stimulates the activation of pro-urokinase and is the preferential substrate of human plasmin

1993 • 19 citations

Free radical-induced fibrinogen coagulation: modulation of neofibe formation by concentration, pH and temperature.

1991 • 11 citations

Effect of oxidants on proteases of the fibrinolytic system: Possible role for methionine residues in the interaction between tissue type plasminogen activator and fibrin

1991 • 11 citations