Cyclic AMP‐mediated alteration of the CD2 activation process in human T lymphocytes. Preferential inhibition of the phosphoinositide cycle‐related transduction pathway

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Modulation of Inflammation and Immunity by Cyclic AMP

1974 • 923 citations

Calcium-mobilizing receptors, polyphosphoinositides, and the generation of second messengers.

1986 • 831 citations

Suppression of human T-cell mitogenesis by prostaglandin. Existence of a prostaglandin-producing suppressor cell.

1977 • 797 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Regulation of the immune response by prostaglandins

1983 • 717 citations

Leukocyte Typing II

1986 • 688 citations

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

1987 • 524 citations

Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.

1978 • 489 citations

Prostaglandin E inhibits the production of human interleukin 2.

1982 • 423 citations

Effects of Prostaglandins on Adenosine 3′,5′-Monophosphate Levels in Fat and Other Tissues

1968 • 357 citations

Phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: Lipids in search of a function

1982 • 242 citations

Mitogens increase phosphorylation of phosphoinositides in thymocytes

1984 • 223 citations

Phosphoinositide interconversion in thrombin-stimulated human platelets.

1985 • 205 citations

The mechanism of inhibition of human IL 2 production.

1982 • 189 citations

Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.

1983 • 181 citations

Multiple kinases and signal transduction. Phosphorylation of the T cell antigen receptor complex.

1987 • 168 citations

Inhibitory effect of prostaglandin E2, forskolin, and dibutyryl cAMP on arachidonic acid release and inositol phospholipid metabolism in guinea pig neutrophils.

1986 • 164 citations

Phosphatidylinositol-specific phospholipase-C of platelets: Association with 1,2-diacylglycerol-kinase and inhibition by cyclic-AMP

1979 • 161 citations

Transmembrane signalling via the T11‐dependent pathway of human T cell activation. Evidence for the involvement of 1,2‐diacylglycerol and inositol phosphates

1987 • 137 citations

Signal transduction and intracellular events in T-lymphocyte activation

1986 • 134 citations

Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes.

1988 • 129 citations

Phenomenon of human T cells rosetting with sheep erythrocytes analyzed with monoclonal antibodies. "Modulation" of a partially hidden epitope determining the conditions of interaction between T cells and erythrocytes

1982 • 104 citations

Inhibitory action of adenosine 3′,5′-monophosphate on phosphatidylinositol turnover: Difference in tissue response

1982 • 102 citations

Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.

1987 • 92 citations

Tumor promoters in conjunction with calcium ionophores mimic antigenic stimulation by reactivation of alloantigen-primed murine T lymphocytes.

1985 • 83 citations

Phytohemagglutinin induces rapid degradation of phosphatidylinositol 4,5-bisphosphate and transient accumulation of phosphatidic acid and diacylglycerol in a human T lymphoblastoid cell line, CCRF-CEM.

1983 • 65 citations

Antigen recognition by a human T cell clone leads to increases in inositol trisphosphate.

1987 • 60 citations

Stimulation of the antigen receptor on WEHI-231 B lymphoma cells results in a voltage-independent increase in cytoplasmic calcium.

1986 • 59 citations

Phytohemagglutinin induces rapid degradation of phosphatidylinositol 4, 5-bisphosphate and transient accumulation of phosphatidic acid and diacylglycerol in a human T lymphoblastoid cell line, CCRF-CEM

1983 • 48 citations

Breakdown of phosphatidylinositol 4,5-bisphosphate in a T-cell leukaemia line stimulated by phytohaemagglutinin is not dependent on Ca2+ mobilization

1985 • 35 citations

Antigen‐specific proliferative human T cell clones with specificity for diphtheria toxoid: genetic and molecular restriction by class II antigens

1984 • 22 citations

Differential inhibition of human antigen-specific T cell clone proliferative responses by distinct monoclonal anti-HLA-DR antibodies.

1984 • 21 citations

T Cell Activation by CD3 Antibodies

1986 • 12 citations

Triggering of the phosphoinositide transduction pathway by a monoclonal antibody specific for the human γ/δ T cell receptor

1988 • 12 citations