T Cell Activation by CD3 Antibodies

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Simple and rapid measurement of human T lymphocytes and their subclasses in peripheral blood.

1980 • 463 citations

TREATMENT OF ACUTE RENAL ALLOGRAFT REJECTION WITH OKT3 MONOCLONAL ANTIBODY

1981 • 389 citations

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells

1983 • 333 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

γ-Interferon is one of several direct B cell-maturing lymphokines

1984 • 237 citations

Interferon-gamma induces enhanced expression of Ia and H-2 antigens on B lymphoid, macrophage, and myeloid cell lines.

1983 • 228 citations

Induction of Ia and H-2 antigens on a macrophage cell line by immune interferon.

1983 • 227 citations

USE OF ANTI-T-CELL MONOCLONAL ANTIBODY OKT3 TO PREVENT ACUTE GRAFT-VERSUS-HOST DISEASE IN ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ACUTE LEUKAEMIA

1982 • 220 citations

Role of γ-interferon in antibody-producing responses

1984 • 203 citations

Human in vivo antigenic modulation induced by the anti‐T cell OKT3 monoclonal antibody

1982 • 199 citations

Mechanism of T lymphocyte activation by OKT3 antibodies. A general model for T cell induction

1984 • 81 citations

Human T lymphocyte activation by monoclonal antibodies; OKT3, but not UCHT1, triggers mitogenesis via an interleukin 2-dependent mechanism.

1984 • 71 citations

Ethnic differences in the lymphocyte proliferative response induced by a murine IgG1 antibody, Leu-4, to the T3 molecule

1984 • 66 citations

OKT8 antibody inhibits OKT3-induced IL 2 production and proliferation in OKT8+ cells.

1983 • 62 citations

The Fc portion of intact IgG blocks stimulation of human PBMC by anti-T3.

1984 • 49 citations

Inhibition of lymphocyte proliferation by monoclonal antibody directed against the T3 antigen on human T cells

1984 • 37 citations

Monoclonal Antibodies for the Diagnosis and Treatment of Transplant Rejection

1984 • 36 citations

Immune interferon induction by a monoclonal antibody specific for human T cells

1981 • 20 citations

Ia- and IgG-Fc receptor-positive accessory cell sustains peripheral T lymphocyte but not thymocyte mitogenesis induced by OKT3 monoclonal antibody

1984 • 8 citations