A Role for p75 Neurotrophin Receptor in the Control of Hair Follicle Morphogenesis

Physiology of the Neurotrophins

1996 • 1,908 citations

The Biology of Hair Follicles

1999 • 1,312 citations

The Trk family of neurotrophin receptors

1994 • 1,271 citations

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1994 • 1,065 citations

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1992 • 960 citations

The secret life of the hair follicle

1992 • 919 citations

Functional Interactions of Neurotrophins and Neurotrophin Receptors

1995 • 825 citations

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75

1996 • 768 citations

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1996 • 750 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Sonic hedgehog signaling is essential for hair development

1998 • 742 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

The nerve growth factor family of receptors

1992 • 649 citations

Induction of hair growth by implantation of cultured dermal papilla cells

1984 • 623 citations

Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A)

1990 • 616 citations

The Function of KGF in Morphogenesis of Epithelium and Reepithelialization of Wounds

1994 • 597 citations

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

1992 • 552 citations

Keratinocyte growth factor is required for hair development but not for wound healing.

1996 • 541 citations

A Comprehensive Guide for the Recognition and Classification of Distinct Stages of Hair Follicle Morphogenesis

1999 • 535 citations

The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death

1998 • 500 citations

The p75 neurotrophin receptor

1994 • 480 citations

Naturally Occurring Truncated trkB Receptors Have Dominant Inhibitory Effects on Brain-Derived Neurotrophic Factor Signaling

1996 • 472 citations

Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate.

1995 • 471 citations

The coat of the mouse (Mus musculus)

1926 • 434 citations

Noggin is a mesenchymally derived stimulator of hair-follicle induction

1999 • 411 citations

Analysis of apoptosis during hair follicle regression (catagen)

1997 • 353 citations

Keratinocyte Growth Factor: A Unique Player in Epithelial Repair Processes

1998 • 345 citations

Interleukin-15 protects from lethal apoptosis in vivo

1997 • 339 citations

Cellular localization of the Trk neurotrophin receptor family in human non-neuronal tissues.

1996 • 274 citations

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.

1993 • 263 citations

Apoptosis in human skin development: Morphogenesis, periderm, and stem cells

1994 • 259 citations

Telogen skin contains an inhibitor of hair growth

1990 • 235 citations

Signalling through the neurotrophin receptor p75NTR

1997 • 221 citations

Neurotrophins Live or Let Die: Does p75NTR Decide?

1997 • 211 citations

Keratinocyte growth factor is an important endogenous mediator of hair follicle growth, development, and differentiation. Normalization of the nu/nu follicular differentiation defect and amelioration of chemotherapy-induced alopecia.

1995 • 211 citations

Fibroblast growth factor signalling in the hair growth cycle: Expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle

1996 • 189 citations

Dependence of Kidney Morphogenesis on the Expression of Nerve Growth Factor Receptor

1991 • 184 citations

Alkaline phosphatase activity and localization during the murine hair cycle

1994 • 175 citations

The TGF-β2 Isoform Is Both a Required and Sufficient Inducer of Murine Hair Follicle Morphogenesis

1999 • 162 citations

HAIR FOLLICLE GROWTH CONTROLS

1996 • 152 citations

Splitting Hairs

1998 • 151 citations

Spatiotemporal patterns of expression of NGF and the low-affinity NGF receptor in rat embryos suggest functional roles in tissue morphogenesis and myogenesis

1992 • 147 citations

Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin

1997 • 141 citations

Involvement of hepatocyte growth factor/scatter factor and Met receptor signaling in hair follicle morphogenesis and cycling

2000 • 138 citations

DERMAL-EPIDERMAL INTERACTIONS

1996 • 127 citations

Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling

1997 • 126 citations

p75 ^NTR : A Receptor After All

1996 • 120 citations

Mesenchymal and Neuronal Cell Expression of the p75 Neurotrophin Receptor Gene Occur by Different Mechanisms

1995 • 118 citations

Multiple functions for NGF receptor in developing, aging and injured rat teeth are suggested by epithelial, mesenchymal and neural immunoreactivity

1990 • 114 citations

A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin

1997 • 111 citations

Immortalization and controlledin vitro differentiation of murine multipotent neural crest stem cells

1997 • 110 citations

Neural Mechanisms of Hair Growth Control

1997 • 108 citations

Changes in Expression of Apoptosis-Associated Genes in Skin Mark Early Catagen

1995 • 100 citations

Patterns of Proliferation and Apoptosis during Murine Hair Follicle Morphogenesis

2001 • 98 citations

A new role for neurotrophins: involvement of brain‐derived neurotrophic factor and neurotrophin‐4 in hair cycle control

1999 • 97 citations

Distribution and changing density of gamma-delta T cells in murine skin during the induced hair cycle

1994 • 90 citations

Expression of neurotrophin receptors during rat tooth development is developmentally regulated, independent of innervation, and suggests functions in the regulation of morphogenesis and innervation

1996 • 89 citations

A New Role for Neurotrophin-3

1998 • 89 citations

Local Injection of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) Alters Cyclic Growth of Murine Hair Follicles

1998 • 84 citations

The Neurotrophin Receptor p75 Binds Neurotrophin-3 on Sympathetic Neurons with High Affinity and Specificity

1997 • 77 citations

Changing Patterns of Cell Adhesion Molecules during Mouse Pelage Hair Follicle Development

1996 • 77 citations

Hair follicle embryogenesis in the human. Characterization of events in vivo and in vitro.

1991 • 65 citations

Fibroblast growth factor and epidermal growth factor in hair development

1993 • 64 citations

Dynamics of Merkel Cell Patterns in Developing Hair Follicles in the Dorsal Skin of Mice, Demonstrated by a Monoclonal Antibody to Mouse Keratin 8

1995 • 64 citations

Evidence for the participation of nerve growth factor and its low-affinity receptor (p75NTR) in the regulation of the myogenic program

1998 • 63 citations

Neurotrophin-3 Involvement in the Regulation of Hair Follicle Morphogenesis

1998 • 63 citations

Merkel cell distribution in human hair follicles of the fetal and adult scalp

1994 • 63 citations

Distinct Patterns of NCAM Expression Are Associated with Defined Stages of Murine Hair Follicle Morphogenesis and Regression

1998 • 61 citations

p75NTR and Trk receptors are expressed in reciprocal patterns in a wide variety of non-neural tissues during rat embryonic development, indicating independent receptor functions.

1998 • 60 citations

Hair Follicle Embryogenesis in the Human

1991 • 59 citations

Expression of morphogens during human follicle development in vivo and a model for studying follicle morphogenesis in vitro

1993 • 58 citations

Fibroblast Growth Factor Influences the Development and Cycling of Murine Hair Follicles

1993 • 58 citations

Cell Cycle Phase-Specific Surface Expression of Nerve Growth Factor Receptors TrkA and p75^NTR

1998 • 57 citations

p75NTR andTrk receptors are expressed in reciprocal patterns in a wide variety of non-neural tissues during rat embryonic development, indicating independent receptor functions

1998 • 54 citations

Role of the low-affinity NGF receptor (p75) in survival of retinal bipolar cells

1998 • 47 citations

Nerve growth factor receptor expression in fetal, mature, and diseased human kidneys.

1993 • 41 citations

Regulation of nerve growth factor and its low-affinity receptor (p75NTR) during myogenic differentiation

1998 • 38 citations

Expression of Morphogens During Human Follicle Development In Vivo and a Model for Studying Follicle Morphogenesis In Vitro.

1993 • 36 citations

Expression of the low‐affinity NGF receptor during human muscle development, regeneration, and in tissue culture

1994 • 34 citations

Low‐affinity nerve growth factor receptor is expressed during testicular morphogenesis and in germ cells at specific stages of spermatogenesis

1994 • 30 citations

Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development.

1993 • 30 citations

BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin

1998 • 27 citations

Expression of transforming growth factor beta isoforms and their receptors during hair growth phases in mice.

1996 • 22 citations

Inhibition of hair growth by subcutaneous injection of a sympathetic neurotoxin, 6-hydroxydopamine in neonatal mice

1995 • 16 citations

Peroxisomes and related particles in animal tissues. Cell Biology Monographs, 7

1981 • 8 citations

Expression of the low-affinity p75 nerve growth factor receptor in the developing rat pituitary gland.

1997 • 7 citations

In situ [H]thymidine labelling of human hair papilla: an in vitro autoradiographic study

1992 • 6 citations