Expression of neurotrophin receptors during rat tooth development is developmentally regulated, independent of innervation, and suggests functions in the regulation of morphogenesis and innervation

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1994 • 1,271 citations

The Trk family of neurotrophin receptors

1994 • 1,271 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system

1992 • 960 citations

Gene transfer and molecular cloning of the rat nerve growth factor receptor

1987 • 946 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

Induction of Apoptosis by the Low-Affinity NGF Receptor

1993 • 774 citations

Role of transforming growth factor-beta in the development of the mouse embryo.

1987 • 760 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ

1988 • 659 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1994 • 620 citations

An immunohistochemical study of the nerve growth factor receptor in developing rats

1988 • 610 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Molecular and biochemical characterization of the human trk proto-oncogene.

1989 • 600 citations

Molecular cloning of rat trkC and distribution of cells expressing messenger RNAs for members of the trk family in the rat central nervous system

1992 • 592 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

Functional analysis of activins during mammalian development

1995 • 579 citations

The induction of odontogenesis in non-dental mesenchyme combined with early murine mandibular arch epithelium

1987 • 556 citations

Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves: ultrastructural location, suppression by axonal contact, and binding properties

1988 • 539 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Cells Expressing mRNA for Neurotrophins and their Receptors During Embryonic Rat Development

1992 • 499 citations

The p75 neurotrophin receptor

1994 • 480 citations

Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.

1992 • 458 citations

Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs.

1995 • 439 citations

Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene.

1994 • 427 citations

Developmental expression of two murine fibroblast growth factor receptors, fig and bek

1991 • 397 citations

Nerve growth factor induces growth and differentiation of human B lymphocytes.

1989 • 386 citations

Alternative forms of rat TrkC with different functional capabilities

1993 • 374 citations

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development.

1994 • 371 citations

Expression of the trk proto-oncogene is restricted to the sensory cranial and spinal ganglia of neural crest origin in mouse development.

1990 • 342 citations

Tissue interactions in embryonic mouse tooth germs: II. The inductive role of the dental papilla

1970 • 319 citations

Expression and possible function of nerve growth factor receptors on Schwann cells

1988 • 304 citations

Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear

1993 • 300 citations

Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape

1992 • 296 citations

trkC, a receptor for neurotrophin-3, is widely expressed in the developing nervous system and in non-neuronal tissues

1993 • 293 citations

The rat trkC locus encodes multiple neurogenic receptors that exhibit differential response to neurotrophin-3 in PC12 cells

1993 • 290 citations

Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4

1996 • 289 citations

Effects of dentin proteins, transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein 2 (BMP2) on the differentiation of odontoblast in vitro.

1992 • 280 citations

The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro

1991 • 256 citations

Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat

1988 • 245 citations

Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation

1994 • 204 citations

Evidence for nerve growth factor-mediated paracrine effects in human epidermis.

1991 • 202 citations

Changes in the distribution of tenascin during tooth development

1987 • 190 citations

Associations between transforming growth factor β1 RNA expression and epithelial – mesenchymal interactions during tooth morphogenesis

1991 • 187 citations

Dependence of Kidney Morphogenesis on the Expression of Nerve Growth Factor Receptor

1991 • 184 citations

Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule.

1992 • 158 citations

Multiple functions for NGF receptor in developing, aging and injured rat teeth are suggested by epithelial, mesenchymal and neural immunoreactivity

1990 • 114 citations

Expression of the NGF receptor gene in sensory neurons and their cutaneous targets prior to and during innervation

1990 • 113 citations

In situ hybridization and the three-dimensional reconstrt1ction of serial sections

1990 • 112 citations

Altered Expression of NGF and P75 NGF-receptor by Fibroblasts of Injured Teeth Precedes Sensory Nerve Sprouting

1992 • 103 citations

Neurotrophic Factors: Switching neurotrophin dependence

1994 • 96 citations

A histological study of the innervation of developing mouse teeth.

1983 • 91 citations

An experimental study of timing and topography of early tooth development in the mouse embryo with an analysis of the role of innervation

1986 • 88 citations

The synthesis of nerve growth factor (NGF) in developing skin is independent of innervation

1988 • 84 citations

Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth

1993 • 82 citations

Immunohistochemical localization of nerve growth factor (NGF) and NGF receptor (NGF-R) in the developing first molar tooth of the rat

1992 • 74 citations

Nonneuronal cells from chick sympathetic and dorsal root sensory ganglia express catecholamine uptake and receptors for nerve growth factor during development

1985 • 67 citations

Innervation of teeth: qualitative, quantitative, and developmental assessment.

1985 • 66 citations

Cell-matrix interactions in tooth development.

1989 • 64 citations

Session III: Innervation of the Dentin, Predentin, and Pulp — H.O. Trowbridge, Chairman

1985 • 62 citations

Differentiation of odontogenic tissues in organ culture

1976 • 55 citations

Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar

1993 • 55 citations

Development of Teeth in Tissue Culture

1967 • 39 citations

Immunohistochemical analysis of pulpal innervation in developing rat molars

1991 • 37 citations

Transient and recurrent expression of the Egr-1 gene in epithelial and mesenchymal cells during tooth morphogenesis suggests involvement in tissue interactions and in determination of cell fate

1992 • 34 citations

Appearance of nerve growth factor receptors on cultured neural crest cells

1985 • 33 citations

Effects of postnatal anti-nerve growth factor serum exposure on development of apical nerves of the rat molar

1994 • 33 citations

A histochemical study of the cholinergic and adrenergic innervation of the developing teeth and oral tissues in the mouse

1983 • 11 citations