Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases

Basic local alignment search tool

1990 • 87,358 citations

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study

1990 • 5,586 citations

The PROSITE database, its status in 1999

1999 • 1,109 citations

The Genetic Basis for Cardiomyopathy

2001 • 1,049 citations

Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

1998 • 848 citations

Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism.

1993 • 678 citations

Stretching cardiac myocytes stimulates protooncogene expression.

1990 • 470 citations

Mechanical loading activates mitogen-activated protein kinase and S6 peptide kinase in cultured rat cardiac myocytes

1993 • 290 citations

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

2001 • 280 citations

Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

1999 • 246 citations

Angiotensin II Activates RhoA in Cardiac Myocytes

1998 • 224 citations

The Low Molecular Weight GTPase Rho Regulates Myofibril Formation and Organization in Neonatal Rat Ventricular Myocytes

1998 • 194 citations

The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains.

1996 • 167 citations

Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos

2000 • 165 citations

Small Guanine Nucleotide-Binding Proteins and Myocardial Hypertrophy

2000 • 158 citations

[16] Discovering and understanding genes in human DNA sequence using GRAIL

1996 • 136 citations

Kalirin, a Cytosolic Protein with Spectrin-like and GDP/GTP Exchange Factor-like Domains That Interacts with Peptidylglycine α-Amidating Monooxygenase, an Integral Membrane Peptide-processing Enzyme

1997 • 121 citations

Prediction of the Coding Sequences of Unidentified Human Genes. XVIII. The Complete Sequences of 100 New cDNA Clones from Brain Which Code for Large Proteins in vitro

2000 • 106 citations

Striated Muscle Preferentially Expressed Genes α and β Are Two Serine/Threonine Protein Kinases Derived from the Same Gene as the Aortic Preferentially Expressed Gene-1

2000 • 61 citations

Molecular and cellular biology of heart failure

1996 • 51 citations

Studies on the function of Rho A protein in cardiac myofibrillogenesis

1997 • 43 citations

Duet is a novel serine/threonine kinase with Dbl-Homology (DH) and Pleckstrin-Homology (PH) domains

1999 • 38 citations

The Trio Guanine Nucleotide Exchange Factor Is a RhoA Target

2000 • 35 citations

Molecular cloning of the human HAND2 gene

1998 • 23 citations