Interactions between cancer cells and the microvasculature: a rate-regulator for metastasis

Biomechanics. Mechanical Properties of Living Tissues

1982 • 6,144 citations

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

1889 • 4,920 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Angiogenic Factors

1987 • 3,702 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

1986 • 1,439 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Role of superoxide dismutase in cancer: a review.

1979 • 976 citations

β1-6 Branching of Asn-Linked Oligosaccharides Is Directly Associated with Metastasis

1987 • 929 citations

TUMOR DORMANCY IN VIVO BY PREVENTION OF NEOVASCULARIZATION

1972 • 898 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells.

1986 • 748 citations

Antimetastatic effects associated with platelet reduction.

1968 • 695 citations

Haematogenous metastastic patterns in colonic carcinoma: An analysis of 1541 necropsies

1986 • 654 citations

Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid.

1979 • 652 citations

The Spread of Tumours in the Human Body

1953 • 639 citations

A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells

1986 • 634 citations

Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitors

1987 • 625 citations

Human endothelial cells synthesize and express an Arg-Gly-Asp-directed adhesion receptor involved in attachment to fibrinogen and von Willebrand factor.

1987 • 571 citations

Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites.

1982 • 554 citations

A 125/115-kDa cell surface receptor specific for vitronectin interacts with the arginine-glycine-aspartic acid adhesion sequence derived from fibronectin.

1985 • 517 citations

Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.

1980 • 502 citations

Loss of basement membrane components by invasive tumors but not by their benign counterparts.

1983 • 497 citations

Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.

1986 • 496 citations

Oxidative Autoactivation of Latent Collagenase by Human Neutrophils

1985 • 466 citations

Protein sequence of endothelial glycoprotein IIIa derived from a cDNA clone. Identity with platelet glycoprotein IIIa and similarity to “integrin”.

1987 • 466 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

Elastic area compressibility modulus of red cell membrane

1976 • 447 citations

Isolation of a tumor cell laminin receptor

1983 • 426 citations

Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species.

1987 • 418 citations

Fundamental Aspects of Metastasis

1977 • 412 citations

Cancer metastasis: tumor cell and host organ properties important in metastasis to specific secondary sites

1988 • 405 citations

Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence

1981 • 396 citations

Induction and detection of a human endothelial activation antigen in vivo.

1986 • 378 citations

Handbook of Bioengineering

1987 • 369 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration.

1986 • 354 citations

Heparan Sulfate Degradation: Relation to Tumor Invasive and Metastatic Properties of Mouse B16 Melanoma Sublines

1983 • 350 citations

Role of collagenases in tumor cell invasion

1982 • 340 citations

The Spread of Tumours in the Human Body

1953 • 326 citations

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

1983 • 315 citations

Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials.

1987 • 315 citations

Pulmonary Oxygen Toxicity

1983 • 312 citations

Inhibition of experimental metastasis by castanospermine in mice: blockage of two distinct stages of tumor colonization by oligosaccharide processing inhibitors.

1986 • 311 citations

Inhibition of in vitro tumor cell invasion by Arg-Gly-Asp-containing synthetic peptides [published erratum appears in J Cell Biol 1989 Jun;108(6):following 2546]

1988 • 311 citations

Mechanisms of Angiogenesis

1987 • 304 citations

A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence.

1987 • 302 citations

Detachment of cells from culture substrate by soluble fibronectin peptides.

1985 • 301 citations

Pulmonary Oxygen Toxicity

1985 • 293 citations

Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa

1987 • 291 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Basement membrane changes in breast cancer detected by immunohistochemical staining for laminin.

1981 • 271 citations

Human fibronectin contains distinct adhesion- and motility-promoting domains for metastatic melanoma cells.

1986 • 270 citations

Angiostatic Steroids

1987 • 267 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Migration by haptotaxis of a Schwann cell tumor line to the basement membrane glycoprotein laminin.

1983 • 259 citations

Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis.

1983 • 259 citations

Modulation of the Metastatic Activity of Melanoma Cells by Laminin and Fibronectin

1984 • 258 citations

Pathogenesis of metastasis formation observed in vivo in the rabbit ear chamber.

1958 • 252 citations

Specificity of adhesion between murine tumor cells and capillary endothelium: an in vitro correlate of preferential metastasis in vivo.

1987 • 250 citations

Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL).

1984 • 242 citations

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.

1983 • 241 citations

The role of cell adhesion proteins?laminin and fibronectin?in the movement of malignant and metastatic cells

1985 • 236 citations

American Association of Pathologists president's address. New roles for the endothelium in inflammation and immunity.

1987 • 232 citations

cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors.

1986 • 231 citations

Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a.

1987 • 226 citations

Binding of tissue plasminogen activator to cultured human endothelial cells.

1987 • 223 citations

Solubilization and degradation of subendothelial matrix glycoproteins and proteoglycans by metastatic tumor cells.

1982 • 222 citations

Myeloperoxidase-catalyzed inactivation of alpha 1-protease inhibitor by human neutrophils.

1981 • 222 citations

Structure and interactions of heparan sulfate proteoglycans from a mouse tumor basement membrane

1984 • 214 citations

Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells

1980 • 212 citations

Cysteine proteinases and metastasis

1984 • 211 citations

Cell Surface Glycolipids and Glycoproteins in Malignant Transformation

1983 • 202 citations

Attachment of cells to basement membrane collagen type IV.

1986 • 198 citations

Stimulation of endothelial cell binding of lymphocytes by tumor necrosis factor.

1987 • 197 citations

13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX.

1985 • 196 citations

Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy.

1985 • 194 citations

Biochemistry of Platelets

1986 • 194 citations

Resting platelets contain a substantial centrally located pool of glycoprotein IIb-IIIa complex which may be accessible to some but not other extracellular proteins.

1986 • 191 citations

Interactions of cancer cells with the microvasculature during metastasis ^{1 2}

1988 • 190 citations

Metastatic tumor cell attachment and invasion assay utilizing vascular endothelial cell monolayers.

1982 • 187 citations

Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix.

1987 • 185 citations

Oligosaccharide modification by swainsonine treatment inhibits pulmonary colonization by B16-F10 murine melanoma cells.

1986 • 184 citations

Toward an Understanding of Angiogenesis: Search and Discovery

1985 • 184 citations

Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.

1982 • 182 citations

Plasminogen activator dependent pathways inthe dissemination of human tumor cells in the chick embryo

1988 • 181 citations

Calcium regulation of the platelet membrane glycoprotein IIb-IIIa complex.

1985 • 178 citations

Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.

1985 • 177 citations

Critical factors controlling angiogenesis: cell products, cell matrix, and growth factors.

1986 • 175 citations

Investigation of the biological effects of anti-cell adhesive synthetic peptides that inhibit experimental metastasis of B16-F10 murine melanoma cells.

1988 • 175 citations

Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein Ib.

1985 • 173 citations

Bidirectional control of membrane expression and/or activation of the tumor cell IRGpIIb/IIIa receptor and tumor cell adhesion by lipoxygenase products of arachidonic acid and linoleic acid.

1989 • 173 citations

STUDIES ON CELL DEFORMABILITY

1965 • 168 citations

On the association of glycoprotein Ib and actin-binding protein in human platelets.

1985 • 165 citations

Localization of internal pools of membrane glycoproteins involved in platelet adhesive responses.

1986 • 164 citations

Principles of metastasis

1985 • 160 citations

Morphological study of the interaction of intravascular tumor cells with endothelial cells and subendothelial matrix.

1988 • 158 citations

Thrombospondin, a potentiator of tumor cell metastasis.

1987 • 156 citations

Correlation between circulating cancer cells and incidence of metastases

1983 • 149 citations

Arrest and extravasation of B16 amelanotic melanoma in murine lungs. A light and electron microscopic study.

1985 • 148 citations

Degradation of human glomerular basement membrane by stimulated neutrophils. Activation of a metalloproteinase(s) by reactive oxygen metabolites.

1987 • 147 citations

Collagenolytic mechanisms in tumor cell invasion

1984 • 146 citations

Transpulmonary passage of tumor cell emboli.

1952 • 146 citations

Expression of Collagenase IV (Basement Membrane Collagenase) Activity in Murine Tumor Cell Hybrids That Differ in Metastatic Potential<xref ref-type="fn" rid="FN2">2</xref>

1985 • 145 citations

Principles of Metastasis

1986 • 143 citations

Effect of Natural Protease Inhibitors and a Chemoattractant on Tumor Cell Invasion In Vitro

1982 • 141 citations

Canine left ventricular intramyocardial pressures

1971 • 138 citations

Electron microscopic observations on formation of pulmonary metastases

1975 • 137 citations

Human and bovine endothelial cells synthesize membrane proteins similar to human platelet glycoproteins IIb and IIIa.

1985 • 131 citations

Immunochemical and amino-terminal sequence comparison of two cytoadhesins indicates they contain similar or identical beta subunits and distinct alpha subunits.

1987 • 131 citations

Haematogenous dissemination of cells from human renal adenocarcinomas

1988 • 130 citations

The fate of circulating tumors cells. I. Passage of cells through capillaries.

1961 • 130 citations

Cell locomotion and tumor penetration

1977 • 127 citations

Role of nk cells in the antimetastatic effect of anticoagulant drugs

1984 • 126 citations

Regulation of the synthesis of extracellular matrix components in chondroblasts transformed by a temperature-sensitive mutant of Rous sarcoma virus

1982 • 125 citations

Thrombospondin-induced attachment and spreading of human squamous carcinoma cells

1986 • 124 citations

Collagen and Collagen-derived Fragments Are Chemotactic for Tumor Cells

1981 • 121 citations

Effects of chemotherapeutic drugs on platelet and metastatic tumor cell-endothelial cell interactions as a model for assessing vascular endothelial integrity.

1985 • 121 citations

Intracellular protein catabolism

1977 • 118 citations

The microvascular extracellular matrix. Developmental changes during angiogenesis in the aortic ring-plasma clot model.

1987 • 118 citations

Biosynthesis and metabolism of 15-hydroperoxy-5,8,11,13-eicosatetraenoic acid by human umbilical vein endothelial cells.

1984 • 117 citations

Extracellular matrix destruction by invasive tumor cells

1982 • 117 citations

Concanavalin A induces interactions between surface glycoproteins and the platelet cytoskeleton.

1982 • 117 citations

Promotion of pulmonary metastasis in mice by bleomycin-induced endothelial injury.

1986 • 111 citations

Cancer cell traffic from the lungs to the liver: An example of metastatic inefficiency

1980 • 108 citations

Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

1988 • 107 citations

Implications of endogenous tumor cell surface lectins as mediators of cellular interactions and lung colonization.

1986 • 105 citations

ENERGETICS OF MEMBRANE DEFORMATION AND ADHESION IN CELL AND VESICLE AGGREGATIONa

1983 • 105 citations

Human osteosarcoma cells resistant to detachment by an Arg-Gly-Asp-containing peptide overproduce the fibronectin receptor.

1987 • 102 citations

Enhancement by drugs of metastatic lung nodule formation after intravenous tumour cell injection

1975 • 101 citations

Superoxide generation by the respiratory chain of tumor mitochondria

1987 • 100 citations

Plasmalemmal proteins of cultured vascular endothelial cells exhibit apical-basal polarity: analysis by surface-selective iodination.

1986 • 99 citations

Role of tumor cell glycoproteins immunologically related to glycoproteins Ib and IIb/IIIa in tumor cell‐platelet and tumor cell‐matrix interactions

1988 • 98 citations

Leukocytosis in non hematological malignancies?A possible tumor-associated marker

1986 • 96 citations

Biomechanical destruction of cancer cells in skeletal muscle: a rate-regulator for hematogenous metastasis

1989 • 95 citations

Tumor cell attachment to the vascular endothelium and subsequent degradation of the subendothelial extracellular matrix

1982 • 92 citations

Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites

1985 • 89 citations

Tumours acquire their vasculature by vessel incorporation, not vessel ingrowth

1987 • 89 citations

Endothelialization of embolized tumor cells during metastasis formation

1988 • 87 citations

Regulation of procollagen messenger ribonucleic acid levels in Rous sarcoma virus transformed chick embryo fibroblasts

1981 • 86 citations

The influence of oxygen on viability and proliferation in cellular spheroids

1979 • 85 citations

Expression and function of a putative cell surface receptor for fibronectin in hamster and human cell lines.

1986 • 81 citations

Dynamic interactions between approaching surfaces of biological interest

1983 • 81 citations

Short-term interactions between cell surfaces

1972 • 79 citations

Receptor patching and capping of platelet membranes induced by monoclonal antibodies

1986 • 74 citations

Properties of a plasma membrane-associated cathepsin B-like cysteine proteinase in metastatic B16 melanoma variants.

1987 • 73 citations

Tumor cell-platelet interactions in vitro and their relationship to in vivo arrest of hematogenously circulating tumor cells

1987 • 73 citations

Rheology of Leukocytesa

1987 • 72 citations

Monoclonal antibodies and cancer therapy

1985 • 71 citations

Cell-contact and-architecture of malignant cells and their relationship to metastasis

1987 • 71 citations

Transcriptional control of the fibronectin gene in chick embryo fibroblasts transformed by Rous sarcoma virus.

1983 • 70 citations

Studies on the mechanisms of invasion in cancer. II. In vivo effects of a factor chemotactic for cancer cells

1971 • 69 citations

Interaction of Platelet Membrane Receptors with von Willebrand Factor, Ristocetin, and the Fc Region of Immunoglobulin G

1978 • 67 citations

Lodgement and extravasation of tumour cells in blood-borne metastasis: an electron microscope study

1978 • 67 citations

Tumor progression in metastasis: an experimental approach using lectin resistant tumor variants

1982 • 67 citations

The effect of cyclophosphamide and other drugs on the incidence of pulmonary metastases in mice.

1977 • 66 citations

Do proteases play a role in cancer invasion and metastasis?

1987 • 65 citations

Plasma Membrane-Associated Cysteine Proteinases in Human and Animal Tumors

1987 • 65 citations

Effect of Cytoskeleton-Disrupting Agents on the Metastatic Behavior of Melanoma Cells<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 65 citations

Influence of migratory blood cells on the attachment of tumor cells to vascular endothelium

1984 • 63 citations

Invasion: Experimental and Clinical Implications

1985 • 62 citations

Immunocytochemistry in the identification of vascular invasion in breast cancer.

1984 • 62 citations

Thrombin Receptors of Human Platelets: Thrombin Binding and Antithrombin Properties of Glycoprotein I

1979 • 61 citations

Diversity of Melanoma Plasma Membrane Proteinases: Inhibition of Collagenolytic and Cytolytic Activities by Minocycline<xref ref-type="fn" rid="FN2">2</xref>

1985 • 59 citations

Role of tumor cytoskeleton and membrane glycoprotein IRGpIIb/IIIa in platelet adhesion to tumor cell membrane and tumor cell-induced platelet aggregation.

1988 • 58 citations

Quantitation of tumorigenic disseminating and arrested cancer cells

1984 • 57 citations

The hemodynamic destruction of intravascular cancer cells in relation to myocardial metastasis.

1985 • 56 citations

Expression of platelet glycoprotein Ib alpha in HEL cells.

1986 • 53 citations

Enhancement of pulmonary metastases by x-irradiation in rats bearing mammary cancer

1967 • 53 citations

Inhibition by dihydropyridine class calcium channel blockers of tumor cell-platelet-endothelial cell interactions in vitro and metastasis in vivo

1985 • 53 citations

Glycoprotein Ib in the triton-insoluble (cytoskeletal) fraction of blood platelets

1984 • 49 citations

Dynamic aspects of cancer cell populations in metastasis.

1979 • 49 citations

Promotion of Growth of Tumour Cells in Acutely Inflamed Tissues

1974 • 48 citations

Some speculations on the rate of adhesion of cells to coverslips

1972 • 48 citations

Augmentation of the antimetastatic effect of anticoagulant drugs by immunostimulation in mice.

1987 • 47 citations

Lipoxygenase Products Regulate IRGpllb/llla Receptor Mediated Adhesion of Tumor Cells to Endothelial Cells, Subendothelial Matrix and Fibronectin

1988 • 47 citations

Liver‐to‐lung traffic of cancer cells

1983 • 47 citations

Role of lipoxygenase metabolism in platelet function: Effect of aspirin and salicylate

1986 • 46 citations

Effects of neutrophil-mediated pulmonary endothelial injury on the localization and metastasis of circulating Walker carcinosarcoma cells.

1987 • 46 citations

Modulation of mouse peritoneal macrophage Ia and human peritoneal macrophage HLA-DR expression by alpha 2-macroglobulin "fast" forms.

1987 • 46 citations

Role of platelet membrane in enhancement of tumor cell adhesion to endothelial cell extracellular matrix.

1987 • 44 citations

Pulmonary Inflammation Generates Chemotactic Activity for Tumor Cells and Promotes Lung Metastasis

1985 • 44 citations

Selective inhibition of proteolytic enzymes in an in vivo mouse model for experimental metastasis.

1986 • 43 citations

A fluid mechanical analysis of the velocity, adhesion, and destruction of cancer cells in capillaries during metastasis

1984 • 42 citations

Successful immunotherapy with intraperitoneal Corynebacterium parvum in a murine ovarian cancer model is associated with the recruitment of tumor-lytic neutrophils into the peritoneal cavity.

1984 • 42 citations

Metastasis of a transplantable mammary tumour in rats treated with cyclophosphamide and/or irradiation

1977 • 40 citations

Relationship between the organization and synthesis of vimentin and the metastatic capability of B16 melanoma cells.

1985 • 40 citations

Enhancement by cytotoxic agents of artificial pulmonary metastasis

1977 • 39 citations

Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.

1979 • 38 citations

Tumor metastasis-associated heparanase (heparan sulfate endoglycosidase) activity in human melanoma cells

1986 • 37 citations

Complement and neutrophil-mediated injury of perfused rat lungs.

1986 • 37 citations

Tumor metastasis after hyperoxic injury and repair of the pulmonary endothelium.

1987 • 37 citations

Stimulation of the respiratory burst of murine peritoneal inflammatory neutrophils by conjugation with tumor cells.

1987 • 37 citations

Diversity of human pancreatic cancer cell proteinases: role of cell membrane metalloproteinases in collagenolysis and cytolysis.

1985 • 36 citations

Target organ patterns of tumors in mice following the arterial dissemination of B16 melanoma cells

1984 • 35 citations

Augmentation of B16 melanoma lung colony formation in C57BL/6 mice having marked granulocytosis

1986 • 35 citations

Effects of injury and repair of the pulmonary endothelium on lung metastasis after bleomycin

1986 • 35 citations

Antiangiogenesis as a Strategy for Antimetastasis

1988 • 34 citations

Lipoxygenase regulation of membrane expression of tumor cell glycoproteins and subsequent metastasis.

1989 • 34 citations

Loss of different pericellular matrix components of rat cells transformed with a T-Class ts mutant of rous sarcoma virus

1982 • 34 citations

Mechanical aspects of the lungs as cancer cell-killing organs during hematogenous metastasis

1986 • 33 citations

Lewis lung carcinoma variants with differing metastatic specificities adhere preferentially to different defined extracellular matrix molecules.

1988 • 33 citations

Tumor‐cell‐platelet aggregation does not correlate with metastatic potential of rat 13762NF mammary adenocarcinoma tumor cell clones

1984 • 33 citations

Platelet-aggregating activities of metastasizing tumor cells. V. In situ roles of platelets in hematogenous metastases.

1986 • 33 citations

Amplified pulmonary metastases of a rat rhabdomyosarcoma in response to nitrosourea treatment.

1984 • 33 citations

Platelet-aggregating activities of metastasizing tumor cells. IV. Effects of cell surface modification on thrombin generation, platelet aggregation and subsequent lung colonization.

1986 • 32 citations

Tumor cell locomotion—a factor in metastasis formation? influence of cytochalasin b on a tumor dissemination pattern

1977 • 31 citations

Inhibition of tumor cell induced platelet aggregation by prostacyclin and carbacyclin: an ultrastructural study.

1987 • 31 citations

Altered adhesiveness of tumor cell surface variants with reduced metastasizing capacity – reduced adhesiveness to vascular wall components in culture

1982 • 30 citations

Role of polymorphonuclear leukocytes in the pulmonary clearance of arrested cancer cells.

1983 • 29 citations

Intravascular death of disseminated cancer cells mediated by superoxide anion.

1986 • 29 citations

Role of glycosidases in human ovarian carcinoma cell mediated degradation of subendothelial extracellular matrix.

1987 • 29 citations

Biomechanical destruction of cancer cells in the heart: a rate regulator for hematogenous metastasis.

1988 • 27 citations

Effects of dimethyl sulfoxide (DMSO) on bleomycin-induced pulmonary fibrosis

1985 • 26 citations

Metastasis: Reticuloendothelial system and organ retention of disseminated malignant cells

1980 • 26 citations

The hemodynamic destruction of circulating cancer cells

1987 • 26 citations

Phorbol myristate acetate-induced adherence of Walker 256 carcinosarcoma cells.

1982 • 26 citations

Studies on cell deformability

1969 • 26 citations

Leukocyte kinetics in the microcirculation

1987 • 26 citations

CSF producing gall bladder cancer: Case report and characteristics of the csf produced by tumor cells

1985 • 25 citations

Platelet Enhancement of Tumor Cell Adhesion to Subendothelial Matrix: Role of Platelet Cytoskeleton and Platelet Membrane<xref ref-type="fn" rid="FN2">2</xref>

1987 • 25 citations

Chemiluminescence and oxygen radical generation by Walker carcinosarcoma cells following chemotactic stimulation.

1987 • 24 citations

Enhancement of experimental metastasis by pretreatment of tumour cells with hydroxyurea

1986 • 23 citations

Separation of High and Low Metastatic Subpopulations from Solid Tumors by Centrifugal Elutriation

1988 • 23 citations

Generation of a complement-derived chemotactic factor for tumor cells in experimentally induced peritoneal exudates and its effect on the local metastasis of circulating tumor cells.

1982 • 23 citations

Interstitieller Raum und Mikromilieu in malignen Tumoren

2015 • 22 citations

Differential effects of interleukin-1 and formylmethionylleucylphenylalanine on chemotaxis and human endothelium adhesivity for A549 tumor cells.

1989 • 22 citations

Mechanisms of cancer metastasis : potential therapeutic implications

1986 • 21 citations

Enhancement of artificial lung metastases in mice caused by cyclophosphamide

1979 • 20 citations

Cell surface sialylation of two human tumor cell lines and its correlation with their platelet-activating activity.

1987 • 20 citations

Mechanically induced trauma suffered by cancer cells in passing through pores in polycarbonate membranes.

1985 • 17 citations

The lack of correlation between experimental metastatic potential and platelet aggregating activity of B16 melanoma clones viewed in relation to tumor cell heterogeneity

1987 • 15 citations

Artificial metastases and decrease of fibrinolysis in the nude mouse lung after hemithoracic irradiation

1984 • 14 citations

A human erythroleukemia cell line synthesizes a functionally active glycoprotein IIb-IIIa complex capable of binding fibrinogen

1987 • 14 citations

CANCER CELL DAMAGE AT THE VASCULAR ENDOTHELIUM

1983 • 13 citations

Effect of leukocyte activation on the formation of heterotypic tumor‐cell aggregates in vitro

1985 • 13 citations

The nature of host tissue destruction in tumor invasion

1986 • 12 citations

The Cellular Interactions of Metastatic Tumor Cells with Special Reference to Endothelial Cells and their Basal Lamina-Like Matrix

1984 • 10 citations

Filtrability and Flow Characteristics of Leukemic and Non-Leukemic Tumor Cell Suspension through Polycarbonate Filters in Relation to Hematogenous Spread of Cancer

1979 • 9 citations

ARACHIDONIC ACID METABOLISM IN MURINE FIBROSARCOMA CELLS WITH DIFFERING IN VIVO AND IN VITRO CHARACTERISTICS

1985 • 9 citations

Loss of basement membrane deposits and development of invasive potential by virally‐transformed rat mammary cells are independent of collagenase production

1987 • 8 citations

Effects of the pyrimido-pyrimidine derivative RX-RA 85 on metastatic tumor cell-vascular endothelial cell interactions

1987 • 8 citations

Phorbol ester binding and phorol ester-induced arachidonic acid metabolism in a highly responsive murine fibrosarcoma cell line and in a less-responsive variant

1986 • 7 citations

The role of platelets in metastasis

1987 • 7 citations

Tumor cell interactions with vascular endothelial cells and their extracellular matrix.

1982 • 7 citations

A Critical Overview of the Metastatic Process

1986 • 6 citations

Hydrodynamics of interaction of particles (including cells) with surfaces

1984 • 5 citations

The effectiveness of cis-platinum, cyclophosphamide and melphalan in treating disseminated tumor cells in mice

1987 • 5 citations

Collagenase and plasminogen activator production by blood vessel-associated cells in response to angiogenic preparations.

1985 • 3 citations

The effects of single versus triple intravenous injections of B16 melanoma cells on the development of pulmonary tumors in mice

1985 • 2 citations

THE QUANTITATION OF SOME ASPECTS OF INVASION IN VIVO AND IN VITRO

1985 • 2 citations