Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

Selection of Successive Tumour Lines for Metastasis

1973 • 1,360 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

The Biology of Cancer Invasion and Metastasis

1978 • 819 citations

Cancer metastasis

1982 • 567 citations

Tumor cell autocrine motility factor.

1986 • 539 citations

A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters

1985 • 446 citations

Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

1985 • 415 citations

Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate.

1985 • 387 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Lysosomal Cathepsin B: Correlation with Metastatic Potential

1981 • 370 citations

Competitive inhibition by diacylglycerol of specific phorbol ester binding.

1984 • 306 citations

Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells.

1980 • 261 citations

Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.

1985 • 218 citations

Laminin molecular domains which alter metastasis in a murine model.

1984 • 187 citations

Effects of tunicamycin on B16 metastatic melanoma cell surface glycoproteins and blood-borne arrest and survival properties.

1981 • 178 citations

Tumor invasion and metastasis.

1986 • 156 citations

Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C.

1986 • 144 citations

Hormone- and tumor promoter-induced activation or membrane association of protein kinase C in intact cells

1987 • 138 citations

Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol ester

1984 • 109 citations

Tumor Invasion and Metastasis

1982 • 99 citations

Altered subcellular distribution of protein kinase C (a phorbol ester receptor). Possible role in tumor promotion and the regulation of cell growth: relationship to changes in adenylate cyclase activity.

1985 • 88 citations

Hydrophobic association of calpains with subcellular organelles. Compartmentalization of calpains and the endogenous inhibitor calpastatin in tissues.

1986 • 85 citations

Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinase

1985 • 70 citations

Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells.

1986 • 63 citations

Glycosphingolipids of Metastatic Variant RNA Virus-Transformed Nonproducer Balb/3T3 Cell Lines: Altered Metabolism and Cell Surface Exposure<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 36 citations