Microinjection of cultured cells using red-cell-mediated fusion and osmotic lysis of pinosomes: A review of methods and applications

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

Current Topics in Membranes and Transport

1970 • 1,240 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Mammalian Cell Fusion : Induction of Premature Chromosome Condensation in Interphase Nuclei

1970 • 699 citations

Electric field-induced cell-to-cell fusion

1982 • 580 citations

INTERACTIONS OF LIPOSOMES WITH MAMMALIAN CELLS

1978 • 408 citations

Peroxidase-Catalyzed Halogenation

1976 • 376 citations

Enzyme Loading of Erythrocytes

1973 • 341 citations

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

How are proteins imported into mitochondria?

1983 • 307 citations

Adenovirus-induced release of epidermal growth factor and pseudomonas toxin into the cytosol of KB cells during receptor-mediated endocytosis

1983 • 256 citations

TRANSIENT HOLES IN THE ERYTHROCYTE MEMBRANE DURING HYPOTONIC HEMOLYSIS AND STABLE HOLES IN THE MEMBRANE AFTER LYSIS BY SAPONIN AND LYSOLECITHIN

1967 • 227 citations

Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src).

1981 • 203 citations

The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts.

1983 • 196 citations

Diffusion of injected macromolecules within the cytoplasm of living cells.

1981 • 174 citations

Properties and Biological Effects of Liposomes and their uses in Pharmacology and Toxicology

1978 • 167 citations

Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells.

1982 • 128 citations

Metabolic and Endocrine Physiology

2012 • 128 citations

Injection of foreign substances into single cells by cell fusion

1974 • 127 citations

Studies of membrane fusion.: III. fusion of erythrocytes with polyethylene glycol

1979 • 123 citations

Altered degradation of proteins microinjected into senescent human fibroblasts.

1982 • 122 citations

Degradation of proteins microinjected into IMR-90 human diploid fibroblasts.

1981 • 121 citations

Poly(ethylene glycol), surface potential and cell fusion

1976 • 114 citations

Microinjection of thymidine kinase and bovine serum albumin into mammalian cells by fusion with red blood cells

1975 • 113 citations

Enhanced synthesis and stabilization of Mr 68,000 protein in transformed BALB/c-3T3 cells: candidate for restriction point control of cell growth.

1983 • 111 citations

Studies on the mechanism of polyethylene glycol-mediated cell fusion using fluorescent membrane and cytoplasmic probes.

1983 • 110 citations

Studies on the Origin of ε-N-Methyl-l-lysine in Protein

1965 • 107 citations

Microinjection of the nonhistone chromosomal protein hmg1 into bovine fibroblasts and hela cells

1979 • 106 citations

The selective degradation of injected proteins occurs principally in the cytosol rather than in lysosomes

1981 • 103 citations

"Ultramicroinjection" of macromolecules or small particles into animal cells. A new technique based on virus-induced cell fusion.

1975 • 98 citations

Evidence for the autophagy of microinjected proteins in HeLA cells.

1977 • 95 citations

Lipid-polyethylene glycol interactions: I. Induction of fusion between liposomes

1981 • 94 citations

Turnover of the plasma membrane proteins of hepatoma tissue culture cells.

1976 • 88 citations

Evidence for both prelysosomal and lysosomal intermediates in endocytic pathways.

1984 • 81 citations

Regulation of catabolism of microinjected ribonuclease A requires the amino-terminal 20 amino acids.

1983 • 81 citations

Fluorescence studies on the mechanism of liposome-cell interactions in vitro

1980 • 80 citations

Chapter 22 Red Cell-Mediated Microinjection of Macromolecules into Mammalian Cells

1978 • 78 citations

The components contained in polyethylene glycol of commercial grade (PEG-6,000) as cell fusogen

1981 • 71 citations

Degradation of proteins microinjected into cultured mammalian cells

1979 • 66 citations

Intracellular neutralization of SV40 tumor antigens following microinjection of specific antibody

1980 • 62 citations

Degradation of microinjected proteins: Effects of lysosomotropic agents and inhibitors of autophagy

1983 • 61 citations

Uptake of proteins by red blood cells

1975 • 58 citations

Neutralization of diphtheria toxin in living cells by microinjection of antifragment A contained within resealed erythrocyte ghosts

1978 • 56 citations

Intracellular distribution and degradation of immunoglobulin G and immunoglobulin G fragments injected into HeLa cells.

1983 • 55 citations

Is purified poly(ethylene glycol) able to induce cell fusion?

1982 • 50 citations

Inhibition of DNA synthesis in proliferating human diploid fibroblasts by fusion with senescent cytoplasts*1

1983 • 49 citations

Direct evidence that the protein kinase catalytic subunit mediates the effects of cAMP on tyrosine aminotransferase synthesis.

1983 • 49 citations

Antibodies introduced into living cells by red cell ghosts are functionally stable in the cytoplasm of the cells

1979 • 48 citations

Autophagy of metabolically inert substances injected into fibroblasts in culture

1981 • 47 citations

Studies on the relationship between the degradative rates of proteins in vivo and their isoelectric points

1979 • 46 citations

A quantitative study of ultramicroinjection of macromolecules into animal cells

1976 • 45 citations

Intracellular degradation of hemoglobin transferred into fibroblasts by fusion with red blood cells

1980 • 42 citations

A Microsurgical Methodology for Human Cells in Vitro : Evolution and Applications

1970 • 41 citations

Degradation of microinjected methylated and unmethylated proteins in hepatoma tissue culture cells.

1983 • 35 citations

Phenotypic complementation of the SV40 tsA mutant defect in viral DNA synthesis following microinjection of SV40 T antigen

1978 • 34 citations

Lectins Mimic Insulin in the Induction of Tyrosine Aminotransferase

1981 • 29 citations

Comparative studies on microinjected high-mobility-group chromosomal proteins, HMG1 and HMG2.

1981 • 28 citations

Microinjection of arginase into enzyme-deficient cells with the isolated glycoproteins of sendai virus as fusogen

1981 • 27 citations

Formation of conjugates by ¹²⁵I‐labelled ubiquitin microinjected into cultured hepatoma cells

1982 • 25 citations

Organelle membrane-cell fusion: Destruction of transplanted mitochondrial proteins in hepatocyte monolayers

1982 • 25 citations

Ghost-mediated transfer of human hypoxanthine-guanine phosphoribosyl transferase into deficient Chinese hamster ovary cells by means of polyethylene glycol-induced fusion

1978 • 23 citations

[31] Fusogenic reconstituted sendai virus envelopes as a vehicle for introducing DNA into viable mammalian cells

1983 • 22 citations

Structural Requirements for Hemolytic Activity of F-Glycoprotein of HVJ (Sendai Virus) Studied by Proteolytic Dissection

1983 • 22 citations

Erythrocyte-mediated microinjection, a technique to study protein degradation in muscle cells

1983 • 21 citations

Regulation of the degradation of ¹²⁵I‐labeled glutamine synthetase introduced into cultured hepatoma cells by erythrocyte ghost—mediated injection

1981 • 21 citations

Transfer of tRNAs to somatic cells mediated by Sendai-virus-induced fusion.

1976 • 21 citations

Antibodies to a nucleolar protein are localized in the nucleolus after red blood cell-mediated microinjection.

1983 • 20 citations

Red cell-mediated microinjection of macromolecules into monolayer cultures of mammalian cells

1979 • 20 citations

Microinjection of macromolecules into normal murine lymphocytes by cell fusion technique. I. Quantitative microinjection of antibodies into normal splenic lymphocytes.

1982 • 19 citations

Fused cells are suited for microinjection

1979 • 19 citations

Cellular Microinjection by Cell Fusion: Technique and Applications in Biology and Medicine

1980 • 19 citations

Degradation and localization of IgG injected into friend erythroleukemic cells by fusion with erythrocyte ghosts

1977 • 19 citations

Chemically facilitated microinjection of proteins into intact monolayers of tissue culture cells

1977 • 19 citations

Transfection of KB Cells by Polyethylene Glycol-induced Fusion with Erythrocyte Ghosts Containing Adenovirus Type 2 DNA

1980 • 18 citations

Cell Fusion: CIBA Foundation Symposium 103

1984 • 17 citations

Microinjection of macromolecules into normal murine lymphocytes by means of cell fusion. II. Enhancement and suppression of mitogenic responses by microinjection of monoclonal anti-cyclic AMP into B lymphocytes.

1982 • 17 citations

Immunospecific vesicle targeting facilitates microinjection into lymphocytes.

1983 • 16 citations

Red cell ghost-mediated microinjection of RNA into HeLa cells *1I. A comparison of two techniques for the entrapment and microinjection of tRNA and mRNA

1983 • 15 citations

What Determines the Degradation Rate of an Injected Protein?

1984 • 15 citations

Injection of proteins into primary rat hepatocytes by erythrocyte-mediated techniques

1982 • 9 citations

Fusion-mediated implantation of band 3 into living cells

1983 • 9 citations

IgG induction in a human B cell line by red cell-mediated microinjection of the cytoplasm from T cell factor-stimulated B cells.

1982 • 8 citations

Degradative Fate of Transplanted Proteins

1984 • 8 citations

Red cell ghost-mediated microinjection of RNA into HeLa cells *1II. Cellular translation of protamine mRNA; post-translational modifications and nuclear binding of newly-synthesized protamine

1983 • 6 citations

Small nuclear RNAs and translation

1983 • 4 citations