Degradation of proteins microinjected into IMR-90 human diploid fibroblasts.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

The measurement of lysozyme activity and the ultra-violet inactivation of lysozyme

1952 • 1,118 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells: Part 2

1976 • 1,060 citations

Radioactive Labeling of Proteins in Vitro

1971 • 840 citations

THE ENZYMATIC IODINATION OF THE RED CELL MEMBRANE

1972 • 709 citations

Studies on the Synthesis and Degradation of Proteins of the Endoplasmic Reticulum of Rat Liver

1969 • 538 citations

24 Bovine Pancreatic Ribonuclease

1971 • 437 citations

Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.

1980 • 393 citations

Role of carbohydrates in protein secretion and turnover: Effects of tunicamycin on the major cell surface glycoprotein of chick embryo fibroblasts

1978 • 391 citations

Peroxidase-Catalyzed Halogenation

1976 • 376 citations

Characterization of a New Human Diploid Cell Strain, IMR-90

1977 • 371 citations

Some Factors Which Affect the Enzymatic Digestion of Ribonucleic Acid

1959 • 301 citations

Protein Turnover and Lysosome Function

1978 • 279 citations

Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

1976 • 234 citations

Tritium labeling of proteins to high specific radioactivity by reduction methylation.

1980 • 206 citations

Fibroblasts degrade newly synthesised collagen within the cell before secretion

1978 • 201 citations

Relationship between in vivo degradative rates and isoelectric points of proteins.

1975 • 171 citations

Studies on the Correlation between Size and Relative Degradation Rate of Soluble Proteins

1973 • 165 citations

The effect of protease inhibitors and decreased temperature on the degradation of different classes of proteins in cultured hepatocytes

1979 • 157 citations

General characteristics of protein degradation in diabetes and starvation.

1978 • 125 citations

Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells

1975 • 125 citations

Protein Degradation in Health and Disease

1981 • 124 citations

Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms.

1979 • 120 citations

Protein degradation in human fibroblasts (WI-38). Effects of aging, viral transformation, and amino acid analogs.

1976 • 113 citations

Microinjection of the nonhistone chromosomal protein hmg1 into bovine fibroblasts and hela cells

1979 • 106 citations

A statistical analysis of the relationship between degradative rates and molecular weights of proteins

1975 • 97 citations

Evidence for the autophagy of microinjected proteins in HeLA cells.

1977 • 95 citations

Relationship of the pool of intracellular valine to protein synthesis and degradation in cultured cells.

1976 • 95 citations

Turnover of the plasma membrane proteins of hepatoma tissue culture cells.

1976 • 88 citations

Protein degradation in health and disease.

1980 • 87 citations

[90] Susceptibility to attack by proteolytic enzymes

1967 • 81 citations

Effect of size on the relative rate of degradation of rat liver soluble proteins

1970 • 79 citations

Chapter 22 Red Cell-Mediated Microinjection of Macromolecules into Mammalian Cells

1978 • 78 citations

Inhibition of protein breakdown in cultured cells is a consistent response to growth factors

1980 • 75 citations

Intracellular protein degradation in growing, in density‐inhibited, and in serum‐restricted fibroblast cultures

1977 • 73 citations

Degradation of proteins microinjected into cultured mammalian cells

1979 • 66 citations

Effect of medium composition on protein degradation and DNA synthesis in rat embryo fibroblasts.

1977 • 65 citations

Proteins iodinated by the Chloramine-T method appear to be degraded at an abnormally rapid rate after endocytosis

1980 • 61 citations

Uptake of proteins by red blood cells

1975 • 58 citations

Rapid transfer of non-histone chromosomal proteins to the nucleus of living cells

1978 • 56 citations

Regulation of protein degradation in normal and transformed human cells. Effects of growth state, medium composition, and viral transformation.

1977 • 54 citations

Protein alterations in aging WI38 cells as determined by proteolytic susceptibility

1975 • 51 citations

Isolation and chemical properties of porcine parathyroid hormone

1971 • 50 citations

Antibodies introduced into living cells by red cell ghosts are functionally stable in the cytoplasm of the cells

1979 • 48 citations

Studies on the relationship between the degradative rates of proteins in vivo and their isoelectric points

1979 • 46 citations

[3H]Raffinose, a novel radioactive label for determining organ sites of catabolism of proteins in the circulation.

1979 • 45 citations

Leucine in cultured cells

1977 • 43 citations

Intracellular degradation of hemoglobin transferred into fibroblasts by fusion with red blood cells

1980 • 42 citations

Iodinated Derivatives of Adrenocorticotropic Hormone

1974 • 42 citations

Digestion of an exogenous protein by rat yolksac cultured in vitro

1971 • 35 citations

Renal protein absorption into sub-cellular particles

1971 • 33 citations

Iodination associated inactivation of β-melanocyte stimulating hormone

1979 • 27 citations

Ghost-mediated transfer of human hypoxanthine-guanine phosphoribosyl transferase into deficient Chinese hamster ovary cells by means of polyethylene glycol-induced fusion

1978 • 23 citations

Protein Turnover in Retina

1980 • 22 citations

The Use of Fusion Methods for the Microinjection of Animal Cells

1979 • 20 citations

The synthesis and degradation of membrane proteins.

1973 • 19 citations

Degradation and localization of IgG injected into friend erythroleukemic cells by fusion with erythrocyte ghosts

1977 • 19 citations

General characteristics of normal and stress-enhanced protein degradation in Lemna minor (duckweed)

1980 • 13 citations

Labeling of creatine phosphokinase without loss of enzyme activity

1975 • 11 citations

The dynamic state of Tetrahymena pyriformis cytosol proteins during culture development

1977 • 4 citations

Micro injection of somatic cells

1980 • 3 citations