Degradative Fate of Transplanted Proteins

Radioactive Labeling of Proteins in Vitro

1971 • 840 citations

Inhibition of the Lysosomal Pathway of Protein Degradation in Isolated Rat Hepatocytes by Ammonia, Methylamine, Chloroquine and Leupeptin

1979 • 466 citations

PINOCYTOSIS IN FIBROBLASTS

1974 • 389 citations

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

A high-yield preparative method for isolation of rat liver mitochondria

1977 • 201 citations

Liposome-mediated delivery of deoxyribonucleic acid to cells: enhanced efficiency of delivery by changes in lipid composition and incubation conditions

1981 • 181 citations

Mitochondrial transformation of mammalian cells

1982 • 175 citations

Putative association of mitochondria with a subpopulation of intermediate-sized filaments in cultured human skin fibroblasts

1982 • 125 citations

Protein Degradation in Health and Disease

1981 • 124 citations

Altered degradation of proteins microinjected into senescent human fibroblasts.

1982 • 122 citations

Degradation of proteins microinjected into IMR-90 human diploid fibroblasts.

1981 • 121 citations

Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms.

1979 • 120 citations

Microinjection of thymidine kinase and bovine serum albumin into mammalian cells by fusion with red blood cells

1975 • 113 citations

Degradation of the acetylcholine receptor in cultured muscle cells: Selective inhibitors and the fate of undegraded receptors

1980 • 111 citations

"Ultramicroinjection" of macromolecules or small particles into animal cells. A new technique based on virus-induced cell fusion.

1975 • 98 citations

Evidence for the autophagy of microinjected proteins in HeLA cells.

1977 • 95 citations

The effects of ammonium ions and chloroquine on uptake and degradation of 125I-labeled asialo-fetuin in isolated rat hepatocytes

1980 • 71 citations

Degradation of proteins microinjected into cultured mammalian cells

1979 • 66 citations

Transfer of the hepatocyte receptor for serum asialo-glycoproteins to the plasma membrane of a fibroblast. Acquisition of the hepatocyte receptor functions by mouse L-cells.

1979 • 65 citations

Local anaesthetics increase susceptibility of untransformed cells to agglutination by concanavalin A

1975 • 53 citations

Fluorescence photobleaching recovery measurements of surface lateral mobilities on normal and SV40-transformed mouse fibroblasts

1980 • 41 citations

Insertion of biologically active membrane proteins from rat liver into the plasma membrane of mouse fibroblasts.

1980 • 40 citations

Protein degradation in rat liver during post-natal development

1980 • 39 citations

Proteins of the hepatoma tissue culture cell plasma membrane

1976 • 37 citations

Analytical fractionation of cultured hepatoma cells (HTC cells)

1978 • 28 citations

Studies on the flavins in rat liver mitochondrial outer membranes

1977 • 27 citations

Inhibition of pyruvate carboxylase degradation and total protein breakdown by lysosomotropic agents in 3T3-L1 cells

1983 • 27 citations

Organelle membrane-cell fusion: Destruction of transplanted mitochondrial proteins in hepatocyte monolayers

1982 • 25 citations

The degradation of normal and analogue-containing proteins in MRC-5 fibroblasts

1978 • 24 citations

Ghost-mediated transfer of human hypoxanthine-guanine phosphoribosyl transferase into deficient Chinese hamster ovary cells by means of polyethylene glycol-induced fusion

1978 • 23 citations

Protein degradation in rat liver evidence for populations of protein degradation rates in cellular organelles

1982 • 17 citations

Acetylcholine receptor degradation: study of mechanism of action of inhibitory drugs.

1983 • 14 citations

Degradation of membrane components by Kupffer cell lysosomes.

1981 • 10 citations