Intracellular distribution and degradation of immunoglobulin G and immunoglobulin G fragments injected into HeLa cells.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Intracellular protein topogenesis

1980 • 1,378 citations

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

1980 • 1,005 citations

Separation of univalent fragments from the bivalent rabbit antibody molecule by reduction of disulfide bonds

1960 • 901 citations

Nuclear envelope permeability

1975 • 808 citations

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.

1980 • 727 citations

Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

1977 • 580 citations

A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes.

1977 • 553 citations

ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation.

1980 • 530 citations

Synthesis and transport of the small subunit of chloroplast ribulose bisphosphate carboxylase

1978 • 429 citations

Post-translational transport into intact chloroplasts of a precursor to the small subunit of ribulose-1,5-bisphosphate carboxylase

1978 • 383 citations

Recognition and receptor-mediated uptake of a lysosomal enzyme, α-l-iduronidase, by cultured human fibroblasts

1977 • 354 citations

Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles

1982 • 320 citations

THE RELEASE OF LABELED AMINO ACIDS FROM THE PROTEINS OF RAT LIVER SLICES

1953 • 236 citations

An association between actin and the major histocompatibility antigen H–2

1978 • 226 citations

Intracellular migration of nuclear proteins in Xenopus oocytes

1978 • 221 citations

Inhibition of protein degradation in isolated rat hepatocytes

1977 • 214 citations

Intracellular protein degradation

1993 • 192 citations

Relationship between in vivo degradative rates and isoelectric points of proteins.

1975 • 171 citations

Studies on the Correlation between Size and Relative Degradation Rate of Soluble Proteins

1973 • 165 citations

Injection of foreign substances into single cells by cell fusion

1974 • 127 citations

Isoelectric focusing of peptides

1978 • 123 citations

Intranuclear injection of anti-actin antibodies into Xenopus oocytes blocks chromosome condensation

1979 • 122 citations

Degradation of proteins microinjected into IMR-90 human diploid fibroblasts.

1981 • 121 citations

Microinjection of thymidine kinase and bovine serum albumin into mammalian cells by fusion with red blood cells

1975 • 113 citations

Microinjection of the nonhistone chromosomal protein hmg1 into bovine fibroblasts and hela cells

1979 • 106 citations

The selective degradation of injected proteins occurs principally in the cytosol rather than in lysosomes

1981 • 103 citations

"Ultramicroinjection" of macromolecules or small particles into animal cells. A new technique based on virus-induced cell fusion.

1975 • 98 citations

Evidence for the autophagy of microinjected proteins in HeLA cells.

1977 • 95 citations

Metabolism of individual proteins in exponentially growing Escherichia coli.

1980 • 82 citations

Hinge-regIon deletion localized in the IgG1-globulin Mcg

1973 • 78 citations

Chapter 22 Red Cell-Mediated Microinjection of Macromolecules into Mammalian Cells

1978 • 78 citations

Intracellular protein degradation in growing, in density‐inhibited, and in serum‐restricted fibroblast cultures

1977 • 73 citations

Degradation of proteins microinjected into cultured mammalian cells

1979 • 66 citations

Intracellular neutralization of SV40 tumor antigens following microinjection of specific antibody

1980 • 62 citations

Proteins iodinated by the Chloramine-T method appear to be degraded at an abnormally rapid rate after endocytosis

1980 • 61 citations

Neutralization of diphtheria toxin in living cells by microinjection of antifragment A contained within resealed erythrocyte ghosts

1978 • 56 citations

Antibodies introduced into living cells by red cell ghosts are functionally stable in the cytoplasm of the cells

1979 • 48 citations

Fate of plasma membrane during endocytosis. III. Evidence for incomplete breakdown of immunoglobulins in lysosomes of cultured fibroblasts

1981 • 45 citations

Intracellular degradation of hemoglobin transferred into fibroblasts by fusion with red blood cells

1980 • 42 citations

Turnover of Membrane Proteins in Animal Cells

1975 • 41 citations

Protein degradation in rat liver during post-natal development

1980 • 39 citations

Protein degradation in the mouse blastocyst.

1979 • 38 citations

Studies on the three-dimensional structure of immunoglobulins

1978 • 38 citations

Intracellular stability of diphtheria toxin fragment A in the presence and absence of anti-fragment A antibody.

1982 • 33 citations

Temperature shifts induce the selective loss of alveolar-macrophage plasma membrane components.

1982 • 19 citations

Degradation and localization of IgG injected into friend erythroleukemic cells by fusion with erythrocyte ghosts

1977 • 19 citations

Evidence for changes in nuclear permeability during different physiological states

1971 • 18 citations

A releationship between protein-degradation rates in vivo, isoelectric points, and molecular weights obtained by using density labelling

1979 • 18 citations

The Isotopic Antiglobulin Assay: Application to the Study of Hybrid Cell Membranes

1971 • 17 citations

Multiple pathways of membrane transport

1982 • 10 citations

Red cell-mediated microinjection.

1978 • 10 citations