Control of vertebrate gastrulation: inducing signals and responding genes

TGFβ signals through a heteromeric protein kinase receptor complex

1992 • 1,519 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

1991 • 1,103 citations

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

1991 • 980 citations

Expression pattern of the mouse T gene and its role in mesoderm formation

1990 • 854 citations

Cloning of the T gene required in mesoderm formation in the mouse

1990 • 847 citations

Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid

1991 • 799 citations

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

1989 • 760 citations

The zootype and the phylotypic stage

1993 • 689 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo

1992 • 648 citations

Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation

1993 • 606 citations

Development and evolution

1982 • 601 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1992 • 538 citations

Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.

1991 • 517 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1991 • 501 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm

1992 • 486 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Lithium perturbation and goosecoid expression identify a dorsal specification pathway in the pregastrula zebrafish

1993 • 458 citations

Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus.

1993 • 449 citations

Gastrulation in the mouse: The role of the homeobox gene goosecoid

1992 • 378 citations

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1993 • 365 citations

Organizer-Specific Homeobox Genes in Xenopus laevis Embryos

1991 • 349 citations

Pintallavis, a gene expressed in the organizer and midline cells of frog embryos: involvement in the development of the neural axis

1992 • 332 citations

The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm

1993 • 292 citations

Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos.

1993 • 283 citations

Mesoderm induction and mesoderm-inducing factors in early amphibian development

1989 • 274 citations

A novel, activin-inducible, blastopore lip-specific gene of Xenopus laevis contains a fork head DNA-binding domain.

1992 • 236 citations

Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue

1992 • 228 citations

Determination of the dorsal-ventral axis in eggs of Xenopus laevis: Complete rescue of uv-impaired eggs by oblique orientation before first cleavage

1980 • 226 citations

The causal analysis of development in the past half century: a personal history

1992 • 214 citations

Activin can induce the formation of axial structures and is expressed in the hypoblast of the chick

1990 • 213 citations

The homeobox gene goosecoid controls cell migration in Xenopus embryos

1993 • 186 citations

Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction

1992 • 178 citations

The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus.

1993 • 167 citations

Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm.

1992 • 155 citations

A novel retrovirally induced embryonic lethal mutation in the mouse: assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral integration

1991 • 147 citations

Chimeric analysis of T (Brachyury) gene function

1993 • 118 citations

A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras

1991 • 117 citations

Activin A induced expression of a fork head related gene in posterior chordamesoderm (notochord) of Xenopus laevis embryos

1992 • 114 citations

Insertional mutation of a gene involved in growth regulation of the early mouse embryo

1992 • 104 citations

Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos

1992 • 53 citations

Growth-factor-related proteins that are inducers in early amphibian development may mediate similar steps in amniote (bird) embryogenesis

1991 • 37 citations