Secretory and inductive properties of Drosophila wingless protein in Xenopus oocytes and embryos

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

Mesoderm induction in early Xenopus embryos by heparin-binding growth factors

1987 • 953 citations

The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

1987 • 906 citations

Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

1990 • 896 citations

Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo

1987 • 883 citations

A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β

1987 • 747 citations

[25] In vitro RNA synthesis with SP6 RNA polymerase

1987 • 732 citations

Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

1990 • 660 citations

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1991 • 651 citations

Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures

1990 • 600 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

1988 • 521 citations

Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis

1989 • 518 citations

Injected Wnt RNA induces a complete body axis in Xenopus embryos

1991 • 501 citations

Fate map for the 32-cell stage ofXenopus laevis

1987 • 500 citations

The formation of the mesoderm in urodelean amphibians

1969 • 472 citations

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development.

1990 • 458 citations

Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors

1988 • 452 citations

Distribution of the wingless gene product in drosophila embryos: A protein involved in cell-cell communication

1989 • 452 citations

Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development

1989 • 418 citations

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderminducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis

1991 • 373 citations

The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer

1988 • 367 citations

Effect of the wingless (wg1) mutation on wing and haltere development in Drosophila melanogaster

1976 • 334 citations

Roles of wingless in patterning the larval epidermis of Drosophila

1991 • 295 citations

Early cellular interactions promote embryonic axis formation in Xenopus laevis

1984 • 291 citations

Regional specification within the mesoderm of early embryos of Xenopus laevis

1987 • 286 citations

Fates of the blastomeres of the 16-cell stage Xenopus embryo

1987 • 284 citations

The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix.

1990 • 280 citations

A mesoderm-inducing factor is produced by a Xenopus cell line

1987 • 276 citations

Mesoderm induction and mesoderm-inducing factors in early amphibian development

1989 • 274 citations

From Egg to Embryo

1991 • 261 citations

Lithium-induced respecification of pattern in Xenopus laevis embryos

1986 • 253 citations

Multiple modes of engrailed regulation in the progression towards cell fate determination

1991 • 248 citations

Secretion and movement of wingless protein in the epidermis of the Drosophila embryo

1991 • 244 citations

Improved fluorescent compounds for tracing cell lineage

1985 • 242 citations

Embryonic and imaginal requirements for wingless, a segment-polarity gene in Drosophila

1988 • 228 citations

Determination of the dorsal-ventral axis in eggs of Xenopus laevis: Complete rescue of uv-impaired eggs by oblique orientation before first cleavage

1980 • 226 citations

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1984 • 222 citations

Secreted int-1 protein is associated with the cell surface.

1990 • 215 citations

The development of wingless, a homeotic mutation of Drosophila

1977 • 185 citations

Comparison of Biological Properties and Transforming Potential of Human PDGF-A and PDGF-B Chains

1988 • 178 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

Xwnt-8 modifies the character of mesoderm induced by bFGF in isolated Xenopus ectoderm.

1992 • 155 citations

Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF

1989 • 154 citations

Rapid turnover of the platelet-derived growth factor receptor in sis-transformed cells and reversal by suramin. Implications for the mechanism of autocrine transformation.

1988 • 147 citations

Presence of basic fibroblast growth factor in the early Xenopus embryo

1989 • 144 citations

The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway

1987 • 141 citations

A novel mechanism regulating growth factor association with the cell surface: identification of a PDGF retention domain.

1991 • 131 citations

Export of proteins from oocytes of Xenopus laevis

1979 • 131 citations

A Mouse Macrophage Factor Induces Head Structures and Organizes a Body Axis in Xenopus

1990 • 130 citations

Localized synthesis of the Vg1 protein during early Xenopus development

1989 • 129 citations

Mesoderm induction in Xenopus laevis: a quantitative study using a cell lineage label and tissue-specific antibodies

1985 • 105 citations

The anterior extent of dorsal development of the Xenopus embryonic axis depends on the quantity of organizer in the late blastula

1990 • 102 citations

Developmental expression of the protein product of Vg1, a localized maternal mRNA in the frog Xenopus laevis.

1989 • 95 citations

Prospective Fates of Blastomeres at the 32 Cell Stage of Xenopus laevis Embryos

1971 • 94 citations

The Influence of Topology and Glycosylation on the Fate of Heterologous Secretory Proteins Made in Xenopus Oocytes

1981 • 83 citations

Isolation of cDNAs partially encoding four Xenopus - proteins and characterization of their transient expression during embryonic development

1991 • 77 citations

Isolation of theXenopusbomolog ofint-1/winglessand expression during neurula stages of early development

1989 • 73 citations

Binding to membrane proteins within the endoplasmic reticulum cannot explain the retention of the glucose-regulated protein GRP78 in Xenopus oocytes.

1988 • 67 citations

Spatial distribution of the capacity to initiate a secondary embryo in the 32-cell embryo ofXenopus laevis

1990 • 64 citations

Inducible overexpression and secretion of int-1 protein.

1989 • 62 citations

Nuclear translocation of fibroblast growth factor during Xenopus mesoderm induction

1991 • 59 citations

Whole-Mount Analyses of Cytoskeletal Reorganization and Function during Oogenesis and Early Embryogenesis in Xenopus

1989 • 51 citations

Fate of secretory proteins trapped in oocytes of Xenopus laevis by disruption of the cytoskeleton or by imbalanced subunit synthesis.

1981 • 39 citations

A new method of local vital staining of amphibian embryos using ficoll and "crystals" of Nile Red.

1980 • 37 citations

Protein transport from endoplasmic reticulum to the Golgi complex can occur during meiotic metaphase in Xenopus oocytes.

1989 • 21 citations

Deleted Work

1955 • 0 citations