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CTCF maintains differential methylation at the Igf2/H19 locus

Data up to Jan 2025

Published2002
Citations313
References24

Total Citations Per Year

Abstract

References (24)

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

2000 • 1,706 citations

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

2000 • 1,493 citations

Dnmt3L and the Establishment of Maternal Genomic Imprints

2001 • 1,356 citations

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

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Disruption of imprinting caused by deletion of the H19 gene region in mice

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Spl elements protect a CpG island from de novo methylation

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Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island.

1994 • 597 citations

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

2000 • 439 citations

A paternal–specific methylation imprint marks the alleles of the mouse H19 gene

1995 • 410 citations

Detection and measurement of PCR bias in quantitative methylation analysis of bisulphite-treated DNA

1997 • 383 citations

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1996 • 378 citations

A 5′ 2-Kilobase-Pair Region of the Imprinted Mouse H19 Gene Exhibits Exclusive Paternal Methylation throughout Development

1997 • 341 citations

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1986 • 300 citations

CTCF, a Candidate Trans -Acting Factor for X-Inactivation Choice

2002 • 271 citations

Targeting genes for self-excision in the germ line

1999 • 241 citations

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1992 • 221 citations

A transcriptional insulator at the imprinted H19/Igf2 locus

2000 • 150 citations

H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19

2000 • 139 citations

Genomic Imprinting and Cancer

2006 • 128 citations

The imprinting box of the mouse Igf2r gene

1999 • 121 citations

Igf2 imprinting does not require its own DNA methylation or H19 RNA

1998 • 101 citations

Analysis of Sequence Upstream of the Endogenous H19 Gene Reveals Elements Both Essential and Dispensable for Imprinting

2002 • 78 citations

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CTCF maintains differential methylation at the Igf2/H19 locus (2002) – Nature Genetics | Metascience Observatory Explorer