CTCF maintains differential methylation at the Igf2/H19 locus
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Abstract
References (24)
High sensitivity mapping of methylated cytosines
1994 • 1,863 citations
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
2000 • 1,706 citations
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus
2000 • 1,493 citations
Dnmt3L and the Establishment of Maternal Genomic Imprints
2001 • 1,356 citations
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
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Disruption of imprinting caused by deletion of the H19 gene region in mice
1995 • 765 citations
Spl elements protect a CpG island from de novo methylation
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Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2
1998 • 641 citations
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island.
1994 • 597 citations
Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive
2000 • 439 citations
A paternal–specific methylation imprint marks the alleles of the mouse H19 gene
1995 • 410 citations
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1997 • 383 citations
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1996 • 378 citations
A 5′ 2-Kilobase-Pair Region of the Imprinted Mouse H19 Gene Exhibits Exclusive Paternal Methylation throughout Development
1997 • 341 citations
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1986 • 300 citations
CTCF, a Candidate Trans -Acting Factor for X-Inactivation Choice
2002 • 271 citations
Targeting genes for self-excision in the germ line
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1992 • 221 citations
A transcriptional insulator at the imprinted H19/Igf2 locus
2000 • 150 citations
H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19
2000 • 139 citations
Genomic Imprinting and Cancer
2006 • 128 citations
The imprinting box of the mouse Igf2r gene
1999 • 121 citations
Igf2 imprinting does not require its own DNA methylation or H19 RNA
1998 • 101 citations
Analysis of Sequence Upstream of the Endogenous H19 Gene Reveals Elements Both Essential and Dispensable for Imprinting
2002 • 78 citations