PROLONGATION OF CANINE LIVER ALLOGRAFT SURVIVAL BY A NOVEL IMMUNOSUPPRESSANT, FTY720

FK 506 FOR LIVER, KIDNEY, AND PANCREAS TRANSPLANTATION

1989 • 1,043 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

1998 • 586 citations

Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite.

1994 • 532 citations

South Africa

1985 • 333 citations

THE REJECTION OF RENAL HOMOGRAFTS

1960 • 312 citations

Design, synthesis, and structure-activity relationships of 2-substituted-2-amino-1,3-propanediols: Discovery of a novel immunosuppressant, FTY720

1995 • 306 citations

A NOVEL IMMUNOSUPPRESSANT, FTY720, WITH A UNIQUE MECHANISM OF ACTION, INDUCES LONG-TERM GRAFT ACCEPTANCE IN RAT AND DOG ALLOTRANSPLANTATION1

1996 • 291 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. II. FTY720 Prolongs Skin Allograft Survival by Decreasing T Cell Infiltration into Grafts But Not Cytokine Production In Vivo

1998 • 263 citations

SOUR MILK AND THE TUBERCLE BACILLUS

1946 • 224 citations

FK 506 for human liver, kidney, and pancreas transplantation

1989 • 168 citations

Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction.

1988 • 160 citations

Reconstructive problems in canine liver homotransplantation with special reference to the postoperative role of hepatic venous flow

1962 • 140 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats.

1996 • 127 citations

A new immunosuppressant, FTY720, induces bcl‐2‐associated apoptotic cell death in human lymphocytes

1996 • 121 citations

New Immunosuppressive Drugs: Mechanistic Insights and Potential Therapeutic Advances

1993 • 109 citations

IMMUNOSUPPRESSIVE EFFECTS OF FTY720 ALONE OR IN COMBINATION WITH CYCLOSPORINE AND/OR SIROLIMUS1

1998 • 101 citations

PROPHYLAXIS OF ACUTE RENAL ALLOGRAFT REJECTION USING FTY720 IN COMBINATION WITH SUBTHERAPEUTIC DOSES OF CYCLOSPORINE1

1999 • 73 citations

FTY720, a novel immunosuppressant possessing unique mechanisms. II. Long-term graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A.

1996 • 71 citations

Orthotopic liver transplantation in dogs receiving FK-506.

1987 • 62 citations

An immunosuppressive agent, FTY720, increases intracellular concentration of calcium ion and induces apoptosis in HL‐60

1997 • 52 citations

Prevention of graft rejection and graft-versus-host reaction by a novel immunosuppressant, FTY 720, in rat small bowel transplantation

1997 • 50 citations

Long-term graft acceptance in allografted rats and dogs by treatment with a novel immunosuppressant, FTY720.

1996 • 41 citations

FTY720: a new immunosuppressive agent with novel mechanism(s) of action

1998 • 39 citations

FTY720, a novel immunosuppressive agent, enhances upregulation of the cell adhesion molecular ICAM-1 in TNF-a treated human umbilical vein endothelial cells

1997 • 26 citations

CANINE LIVER TRANSPLANTATION UNDER Nva2-CYCLOSPORINE VERSUS CYCLOSPORINE1

1986 • 25 citations

Animal Research in Liver Transplantation with Special Reference to the Dog

1985 • 21 citations

Dose-dependent study of a novel immunosuppressant, FTY720, with the canine renal allograft transplantation model

1999 • 15 citations

CANINE LIVER TRANSPLANTATION ·UNDER Nva 2 - CYCLOSPORINE VERSUS CYCLOSPORINE 1

1986 • 2 citations