Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite.

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

IMMUNIZATION OF DISSOCIATED SPLEEN CELL CULTURES FROM NORMAL MICE

1967 • 2,062 citations

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

1987 • 1,216 citations

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

1987 • 1,209 citations

Structure of FK506, a novel immunosuppressant isolated from Streptomyces

1987 • 504 citations

Cyclosporin A, ein immunsuppressiv wirksamer Peptidmetabolit ausTrichoderma polysporum(L<scp>INK</scp>ex P<scp>ERS</scp>.)Rifai

1976 • 373 citations

SEROLOGICALLY DEFINED AND LYMPHOCYTE-DEFINED COMPONENTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE MOUSE

1972 • 293 citations

MYRIOCIN, A NEW ANTIFUNGAL ANTIBIOTIC FROM MYRIOCOCCUM ALBOMYCES

1972 • 200 citations

Elucidation of structure and stereochemistry of myriocin. Novel antifungal antibiotic

1973 • 94 citations

Isolation and structure determination of a new antifungal α-hydroxymethyl-α-amino acid

1972 • 77 citations

In vitro growth of murine T cells. II. Growth of in vitro sensitized cells cytotoxic for alloantigens.

1978 • 53 citations

2-Benzoylamino-2-deoxy-2-hydroxymethyl-D-hexono-1,4-lactones: synthesis from D-fructose and utilization in the total synthesis of thermozymocidin (myriocin)

1983 • 40 citations

Total synthesis of (+)-thermozymocidin (myriocin) from D-fructose

1982 • 38 citations

New insecticidal cyclodepsipeptides from the fungus Isaria felina. II. Structure elucidation of Isariins B, C and D.

1981 • 29 citations

Crystal structure and relative configuration of the N-acetyl-γ-lactone of the antifungal antibiotic thermozymocidin

1979 • 17 citations

Fungal Metabolites. X. The Effect of Peptide Antibiotics, Trichosporin-Bs, on the Respiratory Activity of Mitochondria.

1994 • 16 citations

Determination of amino acid sequences in oligopeptides by mass spectrometry VIII. The structure of isariin

1966 • 13 citations